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Can the use of a next generation partograph based on WHO’s latest intrapartum care recommendations improve neonatal outcomes? (PICRINO) Study protocol for a stepped-wedge cluster randomized trial

Background Monitoring labor and childbirth, early recognition, and treatment of complications are critical for preventing adverse birth outcomes. However excessive use of interventions during labor has not been demonstrated to enhance subsequent birth outcomes and may, in fact, pose a risk of harm. The World Health Organization has recently synthesized research from the last decade concerning labo

Challenge of missing data in observational studies : investigating cross-sectional imputation methods for assessing disease activity in axial spondyloarthritis

Objectives We aimed to compare various methods for imputing disease activity in longitudinally collected observational data of patients with axial spondyloarthritis (axSpA). Methods We conducted a simulation study on data from 8583 axSpA patients from ten European registries. Disease activity was assessed by the Axial Spondyloarthritis Disease Activity Score (ASDAS) and the corresponding low disea

Outcomes of Adjunctive Corticosteroid Treatment in Hypoxemic Adults Hospitalized for Mycoplasma pneumoniae Pneumonia : A Retrospective Cohort Study

Background: Corticosteroids appears to be beneficial for severe Mycoplasma pneumoniae pneumonia in children, but data in adults are limited. This study investigated effects of adjunctive corticosteroids in hypoxemic adults with M. pneumoniae pneumonia. Methods: Adults admitted 2013-2017 with verified M. pneumoniae pneumonia and hypoxemia (SpO2 < 93% or oxygen treatment) were included in a cohort.

TOI-5108 b and TOI 5786 b : Two transiting sub-Saturns detected and characterized with TESS, MaHPS, and SOPHIE

We report the discovery and characterization of two sub-Saturns from the Transiting Exoplanet Survey Satellite (TESS) using high- resolution spectroscopic observations from the MaHPS spectrograph at the Wendelstein Observatory and the SOPHIE spectrograph at the Haute-Provence Observatory. Combining photometry from TESS, KeplerCam, LCOGT, and MuSCAT2, along with the radial velocity measurements fro

The Digital Courtroom: Participation, Attendance, Engagement and Consumption

The digitalisation of courtrooms brings both opportunities and challenges to the judicial process, shaping our understandings of trials and their participants in a myriad of, at times, unexpected ways, and transforming how we participate in, attend, engage with, and consume trials. While digital tools offer potential benefits, they can also impact core aspects of judicial integrity, such as the co

Sparse and Structured Modelling of Underwater Acoustic Channel Impulse Responses

In this paper, we consider real-time modelling of an underwater acoustic channel impulse response (CIR), exploiting the inherent structure and sparsity of such channels. Building on the recent development to model acoustic channels using a Kronecker structure, we propose a sparse block updating conjugate gradient algorithm. The method initially compensate for the drift common in underwater measure

A probabilistic Taylor expansion with Gaussian processes

We study a class of Gaussian processes for which the posterior mean, for a particular choice of data, replicates a truncated Taylor expansion of any order. The data consist of derivative evaluations at the expansion point and the prior covariance kernel belongs to the class of Taylor kernels, which can be written in a certain power series form. We discuss and prove some results on maximum likeliho

The Role of AI in Mental Health Applications and Liability

The COVID-19 pandemic has affected the entire area of health care, including care provided to patients with mental health problems. Due to the stressful nature of the pandemic, the number of patients experiencing mental health problems, especially depression or anxiety, has increased. Even well-before the pandemic, Europe struggled with a lack of mental health care, which was especially caused by

Should Liberal Democracy Respect Group Rights that Discriminate against Women and Apostates?1

The paper examines the limits of state interference in proscribing cultural norms by considering gender discrimination, right of people to leave their community free of penalties, denying women appropriate education, and forced or arranged marriages for girls and young women. The discussion opens by reflecting on the discriminatory practices of the Pueblo tribes against their women and analysing a

Aortic valve calcification across stages of dysglycemia in middle-aged individuals from the general population

Background: Aortic valve calcification (AVC) is an underlying pathophysiological mechanism in aortic stenosis, which shares many risk factors with diabetes. However, the association between dysglycemia and early stages of AVC remains unclear. The aim was to examine the associations between stages of dysglycemia and signs of AVC among middle-aged individuals from the general population. Methods: Th

Risk of divorce and likelihood of having additional children among families with children with spina bifida : A Swedish population-based longitudinal register study

Background: To raise a child with disability might present challenges and affect the functioning of the family unit. In this study, the risk of divorce for parents of children with spina bifida and the probability of having additional children were analysed. Methods: Longitudinal, matched case-control, data between 2004 and 2014 from multiple linked Swedish Population Registers were analysed using