Although Δ9-tetrahydrocannabinol (THC) produces analgesia, its effects on nociceptive primary afferents are unknown. These neurons participate not only in pain signaling but also in the local response to tissue injury. Here, we show that THC and cannabinol induce a CB1/CB 2 cannabinoid receptor-independent release of calcitonin gene-related peptide from capsaicin-sensitive perivascular sensory ner

Resetting or bleaching of the luminescence signal is a fundamental factor in luminescence dating. It must occur in nature during the event or process to be dated for an accurate age, but if it happens during sample processing in the laboratory it destroys the sample for dating purposes. In this study, we look into bleaching of quartz optically stimulated luminescence by light in nature and in the

The radiometric distortion of reflected radiation received by the NOAA AVHRR sensor is brought on by the effects of viewing and solar illumination geometry, as well as atmospheric effects. This may lead to a gross underestimation of bioproductivity or crop yield from models which use high temporal resolution NOAA AVHRR data as an input. Accordingly, a simple angular correction method is presented

In clinical practice it may be difficult to evaluate the cause of acute dysphonia and aphonia. With the aim of elucidating the aetiology, diagnosis and management of patients with acute voice disorder, we have studied different populations with acute laryngitis and psychogenic voice disorder (PVD). The results indicate that bacterial infection is common only in patients with acute laryngitis (65%)

Quality of voice after treatment for T1A glottic squamous cell carcinoma was studied in two matched groups of males treated either with CO2 laser cordectomi (n = 18, mean age 65.2 years) or with full dose radiotherapy (n = 18, mean age 65.1 years). All patients had histologically verified invasive squamous cell carcinoma. Fifteen male patients (mean age 63.9 years) without laryngeal disorders were

Photosynthetically Active Radiation (PAR) is important for assessing both the impact of changing land cover on climate, and for modelling productivity on a regional scale, as well as its potential in areas that are vulnerable to food shortfalls. A relatively simple method that generates spatially comprehensive and representative values of PAR at time scales of 10-days (dekads) or longer is describ

The effect of lymph diversion on plasma apolipoprotein A-I levels was studied. In lymph fistula rats apolipoprotein A-I levels in plasma stayed constant in spite of a loss of an equivalent of one-half plasma pool of apolipoprotein A-I per day through the lymph fistula. This indicates that synthesis of apolipoprotein A-I increases or that catabolism of apolipoprotein A-I decreases in a compensatoryThe effect of lymph diversion on plasma apolipoprotein A-I levels was studied. In lymph fistula rats apolipoprotein A-I levels in plasma stayed constant in spite of a loss of an equivalent of one-half plasma pool of apolipoprotein A-I per day through the lymph fistula. This indicates that synthesis of apolipoprotein A-I increases or that catabolism of apolipoprotein A-I decreases in a compensatory

Late Quaternary sedimentary units at Kongsfjordhallet, NW Svalbard, represent five cycles of glaciations and subsequent deglaciations during high relative sea levels. The high sea level events are interpreted as glacioisostatically induced and imply preceding regional glaciations, which we constrain in time by luminescence and radiocarbon ages to just prior to ~ 195, ~ 130, ~ 85, ~ 60, and ~ 15 ka

Cultured rat hepatocytes release the enzyme hepatic lipase. In this study we investigated the effect of cell density on this metabolic function under a variety of experimental conditions. The release of hepatic lipase from cultured rat hepatocytes exhibits a cell-density dependence, the secretion per mg cell protein being increased with increasing cell density. When cell density dependence was tak