Objective: To investigate CITED1 as a potential biomarker of anti-endocrine response and breast cancer recurrence, given its previously determined role in mediating estrogen-dependant transcription. The study is a continuation of earlier work establishing the role of CITED1 in mammary gland development.Results: CITED1 mRNA is associated with estrogen-receptor positivity and selectively expressed i

Since access to justice scholarship has gradually become a more multifaceted, international and empirical endeavour, this special issue illustrates a broader scope of contemporary access to justice research from a multi-disciplinary and socio-legal perspective. The issue gathers contributions from European and US scholars, representing different disciplinary backgrounds, such as law, sociology of

Background: Mental Health Problems are increasing and there is a general lack of sufficient responses and adequate support from health care. In Sweden, Primary Health Care is the first in line Mental Health Service for patients with Mental Health Problems. The first health professional to encounter patients in need of Primary Health Care is often the Public Health Nurse. Previous research has desc

Background: Who can or cannot claim to represent other members within the disability rights movement has been discussed for decades, mainly concerning being disabled as an eligibility prerequisite. Aim(s): The aim is to analyse arguments concerning representational claims within a Swedish disability rights organisation (DHR, Disability Human Rights). Method: Every member of DHR was given the oppor

Fiber-reinforced polymers are highly demanding composites in aerospace and automotive areas because of their excellent mechanical properties such as stiffness and strength-to-weight ratio. The drilling remains the major machining operation applied to composites to provide high-quality holes for joints between parts. Due to composites plied structure, the drilling is accompanied with unusual form m

In this piece, which frames the special issue, “The State of Google Critique and Intervention,” we provide an overview of research focusing on Google as an object of critical study, fleshing out the European interventions that actively attempt to address its dominance. The article begins by mapping out key areas of articulating a Google critique, from the initial focus on ranking and profiling to

This chapter begins by describing how Michael W. Ford founded the Order of Phosphorus (TOPH). Ford’s writings, as well as his organizations, have a pronounced eclectic approach, weaving together several religious tenets, such as Zoroastrian, Sumerian, and Western Judeo/Christian esoteric elements. The Bible of the Adversary (2007) is a key text in Ford’s Luciferian ideology. The chapter then consi

BACKGROUND: Discrepancy in factor IX activity (FIX:C) between one-stage assay (OSA) and chromogenic substrate assay (CSA) in patients with haemophilia B (PwHB) introduces challenges for clinical management.AIM: To study the differences in FIX activity using OSA and CSA in moderate and mild haemophilia B (HB), their impact on classification of severity, and correlation with genotype.METHODS: Single

Objective. The aim of this study was to determine employment outcomes after radiotherapy (RT) for prostate cancer (PCA). Materials and methods. The Danish DREAM database contains information about social benefits paid to Danish citizens. Data are recorded prospectively every week. From the database, it is possible to assess whether a patient is working, on sick leave or retired at a certain time.

In this paper, we present a fully automated generative method for brain tumor segmentation in multi-modal magnetic resonance images. The method is based on the type of generative model often used for segmenting healthy brain tissues, where tissues are modeled by Gaussian mixture models combined with a spatial atlas-based tissue prior. We extend this basic model with a tumor prior, which uses convo

Since the first report of the enhanced permeability and retention (EPR) effect, the research in nanocarrier based antitumor drugs has been intense. The field has been devoted to treatment of cancer by exploiting EPR-based accumulation of nanocarriers in solid tumors, which for many years was considered to be a ubiquitous phenomenon. However, the understanding of differences in the EPR-effect betwe

Background and purpose We analysed the positional and structural stability of a long-term biodegradable liquid fiducial marker (BioXmark) for radiotherapy in patients with locally advanced lung cancer. Material and methods Markers were injected via endoscopic- or endobronchial ultrasound in lymph nodes and reachable primary tumours. Marker volume and Hounsfield Units (HU) changing rates were estim

The ecosystem-atmosphere flux of biogenic volatile organic compounds (BVOCs) has important impacts on tropospheric oxidative capacity and the formation of secondary organic aerosols, influencing air quality and climate. Here we present within-canopy measurements of a set of dominant BVOCs in a managed spruce- and pine-dominated boreal forest located at the ICOS (Integrated Carbon Observation Syste

Analysis of an individual's immunoglobulin or T cell receptor gene repertoire can provide important insights into immune function. High-quality analysis of adaptive immune receptor repertoire sequencing data depends upon accurate and relatively complete germline sets, but current sets are known to be incomplete. Established processes for the review and systematic naming of receptor germline genes

Waste management policies aim to divert waste from lower positions on the waste hierarchy such as landfill and incineration to higher positions in the hierarchy such as energy recovery and recycling. However, empirical evaluations of such policies are scarce. This study highlighted the effect of waste management policies on the amount of waste treated with landfill, incineration, energy recovery aWaste management policies aim to divert waste from lower positions on the waste hierarchy such as landfill and incineration to higher positions in the hierarchy such as energy recovery and recycling. However, empirical evaluations of such policies are scarce. This study highlighted the effect of waste management policies on the amount of waste treated with landfill, incineration, energy recovery a

Since its heyday in the 1960 and 70s, the sociology of literature has been declared dead and gone, yet research related to the field also seems to be reemerging in the first decades of the 21st century. Research relating to the field is scattered across other disciplines, such as literary studies, media studies and cultural studies; indeed, sociology of literature is “everywhere and nowhere”, as J