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A new study by researchers at Lund University supports the notion that patients with type 2 diabetes should be divided into subgroups and given individualised treatment. The study demonstrates that there are distinct epigenetic differences between different groups of patients with type 2 diabetes. The epigenetic markers were also associated with different risks of developing common complications i

https://www.ludc.lu.se/article/epigenetic-markers-predict-complications-patients-type-2-diabetes - 2025-11-25

Epigenetics has become an important tool for researchers endeavoring to understand the causes and development stages of type 2 diabetes. In the future, epigenetic biomarkers could be used to predict type 2 diabetes and individualise its treatment. Diabetes and epigenetics researchers at Lund University summarise some of the most important advancements in a review article published in Nature Review

https://www.ludc.lu.se/article/epigenetics-can-pave-way-individualised-treatment-type-2-diabetes - 2025-11-25

Insulin secretion into the bloodstream requires a protein called CD59. New research led by Lund University shows that the two protein variants that are responsible for this function of CD59 are affected in diabetes. The study has been recently published in PNAS. Insulin affects many bodily functions, and is required for survival. It causes cells to take up glucose from the blood, storage of energy

https://www.ludc.lu.se/article/newly-discovered-protein-variants-are-key-insulin-secretion - 2025-11-25

Why do some people develop type 1 diabetes and others do not? Worldwide, researchers are now collaborating to find the answer to this complex question. Diabetes researchers at Lund University recently contributed data to a new study that shows that type 1 diabetes develops in three different ways in children. This improved understanding makes it possible for scientists to conduct new types of stud

https://www.ludc.lu.se/article/blood-testing-children-leads-better-understanding-type-1-diabetes - 2025-11-25

Three researchers at Lund University Diabetes Centre (LUDC) have each been awarded a project grant of 47,500 euro by the Hjelt Diabetes Foundation. The aim of all three projects is to improve our understanding of diabetes and ultimately enable better treatments of type 2 diabetes and its complications. One of the three projects uses advanced technology to learn more about the mechanisms behind dia

https://www.ludc.lu.se/article/new-funding-hjelt-diabetes-foundation-improve-understanding-diabetes - 2025-11-25

Impaired insulin secretion is closely associated with type 2 diabetes, but the process is not yet fully understood. A new study by researchers at Lund University shows that the Piezo1 ion channel regulates insulin secretion, which means it may be an important target for new diabetes treatments. Type 2 diabetes often occurs because the pancreatic beta cells are unable to produce enough effective in

https://www.ludc.lu.se/article/study-shows-piezo1-ion-channel-plays-important-role-insulin-secretion - 2025-11-25

We were interested to know what our Scientific Advisory Board think about the research currently underway at Lund University Diabetes Centre (LUDC), and invited Flemming Pociot and Søren Brunak from the board to the LUDC retreat in Helsingborg recently. They spent their time at the retreat listening to presentations and getting updates, and were able to provide valuable feedback. A presentation ab

https://www.ludc.lu.se/article/scientific-advisory-board-we-hope-see-more-data-about-subgroups - 2025-11-25

A large-scale faeces and blood sample study indicates strong associations between gut bacteria and metabolites in the blood. Among other findings, the research team behind the study has identified new associations between a common type 2 diabetes drug and the gut microbiome. The study was led by researchers at Uppsala University and Lund University. The role of the gut microbiome in disease and he

https://www.ludc.lu.se/article/gut-microbiome-research-indicates-new-bacteria-and-metformin-associations - 2025-11-25

Since Helena Elding Larsson began her career as a diabetes researcher and paediatrician, she has seen many improvements in the care of patients with diabetes. Her own research focuses on the prevention of the development of type 1 diabetes. Helena Elding Larsson is this year’s recipient of the Medeon stipend, and she will be speaking at the World Diabetes Day Skåne event, in Malmö on November 12th

https://www.ludc.lu.se/article/diabetes-researcher-helena-elding-larsson-wants-prevent-type-1-diabetes-developing - 2025-11-25

Six researchers at Lund University Diabetes Centre (LUDC) were recently awarded grants within medicine and health by the Swedish Research Council (Vetenskapsrådet). The six researchers are members of the strategic research area Excellence of diabetes research in Sweden (EXODIAB) at Lund University. Daniel Agardh, adjunct professor in pediatrics and research group leader in celiac disease and diabe

https://www.ludc.lu.se/article/several-diabetes-researchers-ludc-receive-grants-swedish-research-council - 2025-11-25

How much water do we need to drink to stay healthy? How do different diets affect our metabolism? Studies of various hormones in the body are providing diabetes researchers with new answers to these questions. The goal is to develop individualized treatments and dietary recommendations that could lower the risk of developing obesity and diseases such as type 2 diabetes. The endocrine system and th

https://www.ludc.lu.se/article/learning-more-about-endocrine-system-could-lead-fewer-cases-type-2-diabetes-and-obesity - 2025-11-25

World Diabetes Day in Malmö was all about science. Researchers told the latest on diabetes research from stem cells to diet and the smallest hade the opportunity to becoming scientists - and learn what makes a strawberry a strawberry .  Organisers:Lund University Diabetes Centre, Scania Hospital, Diabetes Society in Malmö/Lund and TEDDY.

https://www.ludc.lu.se/article/world-diabetes-day-malmo-2015 - 2025-11-25

Professor Charlotte Ling at Lund University Diabetes Centre (LUDC) has been awarded a Proof of Concept Grant by the European Research Council, ERC, for the further development of her successful research on epigenetic biomarkers. The innovation-driven research project will investigate biomarkers for predicting who benefits from metformin in the treatment of type 2 diabetes. In her research, Charlot

https://www.ludc.lu.se/article/erc-grant-research-diabetes - 2025-11-25

Tove Fall became a familiar face during the Covid-19 pandemic when she was often seen in Swedish media talking about the spread and progression of the disease in Sweden. She is also an outstanding diabetes researcher who uses large quantities of data to gain a better understanding of the development of diabetes. Tove Fall is now awarded the Leif C. Groop award for outstanding diabetes research for

https://www.ludc.lu.se/article/diabetes-researcher-tove-fall-recipient-leif-c-groop-award-2023 - 2025-11-25

Researchers have identified 395 genes that are differently expressed in people with type 2 diabetes. One of the genes proved to be very strongly associated with impaired insulin secretion. Now, researchers want to investigate if it is possible to use the genetic CRISPR/Cas9 scissors to correct the gene’s activity. The research team’s scientific paper was published in the Journal of Clinical Invest

https://www.ludc.lu.se/article/pax5-gene-strongly-associated-impaired-insulin-secretion-type-2-diabetes - 2025-11-25

A team of researchers led by Daniel E. Coral and Paul W. Franks at LUDC have used human genetics to do a phenome-wide analysis of the degree of genetic dissimilarity between obesity and type 2 diabetes. Together with colleagues from Dundee and Oxford universities in the UK and the Vanderbilt Genetics Institute in the US, the team recently published their findings in the journal Nature Metabolism.

https://www.ludc.lu.se/article/genetic-driven-approach-defining-two-obesity-profiles-convey-highly-concordant-and-discordant - 2025-11-25

Researchers at Lund University have previously shown that type 1 diabetes and type 2 diabetes can be divided into five subgroups, and that there are genetic differences between the four subgroups relating to type 2 diabetes. A research collaboration between Sweden and India now highlights similarities and differences between patient groups in India and Europe. The knowledge can be used to improve

https://www.ludc.lu.se/article/swedish-research-about-different-forms-type-2-diabetes-relevant-indian-people - 2025-11-25

Precision medicine aims to deliver the right treatment to the right person at the right time. What does this mean for people with type 2 diabetes? Some of the research at Lund University Diabetes Centre (LUDC) focuses on the progression of type 2 diabetes to help develop more targeted treatments. Epigenetics can become a useful tool when diabetes care is tailored to the individual. People with typ

https://www.ludc.lu.se/article/epigenetics-and-genetics-help-illustrate-how-diabetes-care-can-be-individualised - 2025-11-25

A common cause of myocardial infarction and stroke is the rupture of atherosclerotic plaques. The exact location of plaque ruptures has previously been unknown, but now researchers at Lund University have mapped this. The research team has also identified an enzyme, a marker, that they hope will help predict who is at risk of having a myocardial infarction or a stroke due to a ruptured atheroscler

https://www.ludc.lu.se/article/new-discoveries-about-where-atherosclerotic-plaques-rupture-can-lead-preventive-treatments - 2025-11-25

Every year, the Bo and Kerstin Hjelt Diabetes Foundation awards three diabetes researchers at Lund University Diabetes Centre (LUDC) each a project grant of 47,500 euro. One of the researchers awarded a grant this year studies atherosclerotic plaques in patients with type 2 diabetes. These patients are more likely to develop cardiovascular disease due to plaque rupture compared to people without t

https://www.ludc.lu.se/article/type-2-diabetes-researchers-receive-support-hjelt-diabetes-foundation - 2025-11-25