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This study aimed to validate the summation methods suggested by ISO 9920. Twenty seven items from an ambulance personnel clothing system were selected for testing. The basic insulation of each garment item (Iclu) was calculated based on the thermal manikin tests. More than 100 realistic clothing combinations were compiled and basic insulation (Icl) of these ensembles was calculated according to IS

BackgroundAssessment and treatment of the acutely ill patient have improved by introducing systematic assessment and accelerated protocols for specific patient groups. Triage systems are widely used, but few studies have investigated the ability of the triage systems in predicting outcome in the unselected acute population. The aim of this study was to quantify the association between the main com

Predation is a well-studied driver of ecological selection on prey traits, which frequently drives divergence in anti-predator performance across environments that vary in predation risk. However, predation also alters prey mortality regimes, where low predation risk often results in higher prey densities and consequently higher intensities of intraspecific resource competition. In addition, preda

Phthalates are widely used in consumer products. Exposure to phthalates can lead to adverse health effects in humans, with early-life exposure being of particular concern. Phthalate exposure occurs mainly through ingestion, inhalation, and dermal absorption. However, our understanding of the relative importance of different exposure routes is incomplete. This study estimated the intake of five pht

Exposure to a cold climate is associated with an increased morbidity and mortality, but the specific mechanisms are largely unknown. People with cardiopulmonary disease and winter endurance athletes are particularly vulnerable. This study aimed to map multiple domains of airway responses to exercise in subzero temperature in healthy individuals. Thirty-one healthy subjects underwent whole-body exp

Introduction: Treatment-induced peripheral neuropathy (TIPN) is a complication of multiple myeloma (MM) treatment. Objective: This real-world, retrospective study used electronic medical record (EMR) data from 3 Swedish clinics to assess the occurrence and economic burden of TIPN in patients with MM. Methods: Eligible patients had an MM diagnosis in the Swedish Cancer Registry between 2006 and 201

BackgroundEvaluation of emergency department (ED) performance remains a difficult task due to the lack of consensus on performance measures that reflects high quality, efficiency, and sustainability.AimTo describe, map, and critically evaluate which performance measures that the published literature regard as being most relevant in assessing overall ED performance.MethodsFollowing the PRISMA guide

Background: The 2017 Alzheimer’s disease (AD) Strategic Biomarker Roadmap (SBR) structured the validation of AD diagnostic biomarkers into 5 phases, systematically assessing analytical validity (Phases 1–2), clinical validity (Phases 3–4), and clinical utility (Phase 5) through primary and secondary Aims. This framework allows to map knowledge gaps and research priorities, accelerating the route t

This article explores news satire engagement and civic motivation, an area of concern in satire scholarship. Focused on what audiences ‘do’ with media, the ways in which young adults who regularly engage in news satire construct political efficacy is studied. Using a qualitative contextualising audience study, including in-depth interviews and focus groups with 31 young adults, a thematic analysis

Unicellular photosynthetic golden algae called diatoms are one of the most abundant silicifying organisms. Diatoms take up silicon and build their frustules, in the form of biogenic silica (BSi), which have high preservation potential, and thus are found in sediments. Around 27 % of the annual dissolved silicon (DSi) delivery from the land to the ocean is retained in lakes and reservoirs in the fo

This article reviews the geology of the Sveconorwegian orogen in south Scandinavia and existing tectonic models for the Mesoproterozoic to Neoproterozoic Sveconorwegian orogeny. It proposes an updated geodynamic scenario of large, hot, long-duration continental collision starting at c. 1065 Ma between proto-Baltica and another plate, presumably Amazonia, in a Rodinia-forming context. An orogenic p

We report on a novel phenomenon of particle cosmology, which features specific cosmological phase transitions via quantum tunnelings through multiple vacua. The latter is inspired by the axiverse ideas, and enables to probe the associated new physics models through a potential observation of specific patterns in the stochastic gravitational waves background. Multiple vacua may induce the nucleatio

Androgen deprivation therapy (ADT) with gonadotropin-releasing hormone (GnRH) agonists and antagonists is the mainstay of advanced prostate cancer treatment. Both drug classes decrease levels of luteinizing hormone and follicle-stimulating hormones (FSH), thereby lowering testosterone to castrate levels. This is associated with adverse events (AEs), including cardiovascular (CV) disorders, bone fr

Objectives: To explore the preoperative, intraoperative, and postoperative dynamics of heparin-binding protein (HBP) in cardiothoracic surgery. Design: This was a prospective, observational study. Setting: The study was conducted at a single university hospital. Participants: Thirty patients undergoing cardiac surgery with cardiopulmonary bypass (CPB) were included, 15 of whom underwent coronary a

The relative role of natural selection and genetic drift in evolution is a major topic of debate in evolutionary biology. Most knowledge spring from a small group of organisms and originate from before it was possible to generate genome-wide data on genetic variation. Hence, it is necessary to extend to a larger number of taxonomic groups, descriptive and hypothesis-based research aiming at unders

Genome scans in recently separated species can inform on molecular mechanisms and evolutionary processes driving divergence. Large-scale polymorphism data from multiple species pairs are also key to investigate the repeatability of divergence-whether radiations tend to show parallel responses to similar selection pressures and/or underlying molecular forces. Here, we used whole-genome resequencing

The Christian monastic tradition has its origins in the Middle East. It has been and remains a constitutive institution in the Oriental Orthodox Churches, which are the Armenian, Coptic, Ethiopian, and Syrian Orthodox Churches. In Armenia, Egypt, Ethiopia, and the Syriac-speaking Christian traditions, the monasteries have been the most important educational institutions in which language and liter