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A Quality Assessment of the ARM-Net Registry Design and Data Collection

Background: Registries are important in rare disease research. The Anorectal Malformation Network (ARM-Net) registry is a well-established European patient registry collecting demographic, clinical, and functional outcome data. We assessed the quality of this registry through review of the structure, data elements, collected data, and user experience. Material and methods: Design and data elements

Medicinsk underrättelsetjänst - delrapport 2

Rapporten utgör den andra av tre delrapporter och redovisar resultatet av forskning på uppdrag av Försvarsmakten.The report is the second of three sub-reports and presents the results of a research commissioned by the Swedish Armed Forces.

Reduced Expression Level of Protein Phosphatase PPM1E Serves to Maintain Insulin Secretion in Type 2 Diabetes

Reversible phosphorylation is an important regulatory mechanism. Regulation of protein phosphorylation in β-cells has been extensively investigated, but less is known about protein dephosphorylation. To understand the role of protein dephosphorylation in β-cells and type 2 diabetes (T2D), we first examined mRNA expression of the type 2C family (PP2C) of protein phosphatases in islets from T2D dono

Clandestine Communications in Cyber-Denied Environments : Numbers stations and radio in the 21st century

Both intelligence operatives and criminals have a constant need to be able to communicate clandestinely, circumventing surveillance efforts carried out by highly capable adversaries. The recent highly-publicized breaches of internet-based clandestine communications technology and targeted malware attacks, in combination with increasingly sophisticated methods for surveillance of internet traffic h

Improving archaeomagnetic dating through new data acquisition and method development

The Earth’s magnetic field (or geomagnetic field) has been measured for hundreds of years, starting with maritime observations from logbooks for navigation purposes to present day real-time recording by satellites. From these records, the geomagnetic field variation throughout recent time is well-understood. In order to study longer term field variations (on the scale of hundreds to thousands of y

Nonlinear brain correlates of trait self-boundarylessness

Alterations of the sense of self induced by meditation include an increased sense of boundarylessness. In this study, we investigatedbehavioural and functional magnetic resonance imaging correlates of trait self-boundarylessness during resting state and the performanceof two experimental tasks. We found that boundarylessness correlated with greater self-endorsement of words related to fluidityand

The Association Between HIV Diagnosis Disclosure and Adherence to Anti-retroviral Therapy among Adolescents Living with HIV in Sub-Saharan Africa: A Systematic Review and Meta-Analysis

IntroductionNine in ten of the world’s 1.74 million adolescents living with human immunodeficiency virus (ALHIV) live in Sub-Saharan Africa. Suboptimal adherence to antiretroviral therapy (ART) and poor viral suppression are important problems among adolescents. To guide intervention efforts in this regard, this review presented pooled estimates on the prevalence of adherence and how it is affecte

Applications in Monocular Computer Vision using Geometry and Learning : Map Merging, 3D Reconstruction and Detection of Geometric Primitives

As the dream of autonomous vehicles moving around in our world comes closer, the problem of robust localization and mapping is essential to solve. In this inherently structured and geometric problem we also want the agents to learn from experience in a data driven fashion. How the modern Neural Network models can be combined with Structure from Motion (SfM) is an interesting research question and As the dream of autonomous vehicles moving around in our world comes closer, the problem of robust localization and mapping is essential to solve. In this inherently structured and geometric problem we also want the agents to learn from experience in a data driven fashion. How the modern Neural Network models can be combined with Structure from Motion (SfM) is an interesting research question and

Form-factor of low-lying Kπ=1+ excitations in rare-earth nuclei

The differential cross section of inelastic electron scattering for the low-lying “collective” Kπ=1+ excitations in rare-earth nuclei is calculated in DWBA by using microscopically calculated transition-densities. In the region of low-momentum transfer (q⪅0.5 fm-1) in which experimental data are available the shape of calcualted cross sections is almost the same for all nuclei and is slightly but

The effect of the presence of quadrupole pairing on the properties of Kπ = 1+ states in doubly even nuclei

The influence of a quadrupole pair interaction on Kπ = 1+ states in rare earth nuclei is investigated using the Quasiparticle Random Phase Approximation. Comparison of the obtained results with available experimental data indicates a rather weak quadrupole pair interaction in these nuclei. The calculation of the B(M1) strength is extended to higher energies to account for the recently observed hig

Deformation dependence of magnetic dipole strength below 4 MeV in doubly even rare earth nuclei

We show: (1) In the presence of the pair correlation the M1 transition strength calculated in the deformed oscillator model has a dependence on the quadrupole deformation parameter δ which is considerably stronger than linear and, in fact, it varies quadratically with δ in the limit of small deformation; (2) The deformation dependence in samarium isotopes calculated using the quasiparticle random

Nature inspired node density estimation for molecular nanonetworks

The problem of estimating the node density in ad hoc networks is a significant one for protocol design. In molecular nanonetworks, the node density estimation problem poses additional challenges due to the limited processing and communication capabilities of the network nodes which necessitate the design of simple to implement distributed solutions, and the diffusion based communication channel wh

Attitudes related to technology for active and healthy aging in a national multigenerational survey

Research is needed to understand attitudes toward and adoption of the broad range of technologies available to support active and healthy aging in different generations. The present article gives an overview of the GenerationTech survey and sample, and describes attitudes and acceptance related to technology in general and as a means to support active and healthy aging. A national survey was condu

Tillgänglighet, användbarhet och universell utformning

När ett barn föds är det mycket i samhället som det ännu inte har träffat på. Ja, faktiskt det mesta. Vem barnet blir och vilka vägar det väljer genom livet kommer att påverkas av många faktorer, däribland utformningen av alla de produkter och miljöer det över tid möter och interagerar med. I detta kapitel ägnar vi oss åt fysiska aspekter av interaktionen mellan individ och samhälle, med fokus på

Towards fault adaptive routing in metasurface controller networks

HyperSurfaces (HSFs) comprise structurally reconfigurable metasurfaces whose electromagnetic properties can be changed via a software interface, using an embed- ded miniaturized network of controllers, enabling novel capabilities in wireless communications, including 5G applications. Resource constraints associated with a hardware testbed of this breakthrough technology, currently under developmen

A field test of computer-vision-based gaze estimation in psychology

Computer-vision-based gaze estimation refers to techniques that estimate gaze direction directly from video recordings of the eyes or face without the need for an eye tracker. Although many such methods exist, their validation is often found in the technical literature (e.g., computer science conference papers). We aimed to (1) identify which computer-vision-based gaze estimation methods are usabl