BACKGROUND: Medium vessel occlusions (MeVO) can be either isolated events (primary), or secondary to thrombus migration from a large vessel occlusion to a medium-sized vessel. Outcomes following endovascular thrombectomy (EVT) in the middle cerebral artery (MCA) may differ between primary and secondary MeVOs. This study aimed to assess the association between primary/secondary MeVOs and clinical o

BACKGROUND: Leukocytes have been reported to have tumor stimulating effects in colorectal cancer, among other malignancies. In line with this, earlier research has shown improved disease-free survival in patients with postoperative neutropenia compared to non-neutropenic patients following cytoreductive surgery (CRS) and hypertherm intraperitoneal chemotherapy (HIPEC).AIM: To evaluate the impact o

Introduction: Patients with substantial comorbidity burden are underrepresented in clinical trials on endovascular thrombectomy (EVT), despite being common in clinical routine care. Therefore, analysis of observational data is needed to evaluate how increasing comorbidity burden affects procedural success rate, complication rate, and clinical outcome following EVT. Patients and methods: We conduct

AIMS: Patients with heart failure (HF) and iron deficiency experience poor health-related quality of life (HRQoL). We evaluated the impact of intravenous (IV) ferric carboxymaltose (FCM) vs. placebo on HRQoL for the AFFIRM-AHF population.METHODS AND RESULTS: The baseline 12-item Kansas City Cardiomyopathy Questionnaire (KCCQ-12), which was completed for 1058 (535 and 523) patients in the FCM and p

INTRODUCTION: Breast cancer, a leading female cancer worldwide, can be influenced by mitochondrial dysfunction. Dysregulation of mitochondria by the nuclear genome may cause breast cancer initiation and progression. However, the comprehensive investigation of mitochondrial-related genes as prognostic marker for the overall survival of early-stage breast cancer patients is still limited.METHODS: To

Liquid foams are dispersions of closely packed gas bubbles within a liquid phase. They are commonly encountered in daily life, such as in food and cosmetics, and are extensively used in industry due to their unique mechanical properties, exhibiting both solid-like and liquid- like behavior. However, predicting the rheological behavior of liquid foams remains a challenge due to the complex interpla

BACKGROUND: Long-term outcomes of percutaneous coronary intervention (PCI) for bifurcation lesions are underexplored. We investigated long-term PCI outcomes for proximal LAD bifurcation lesions involving D1.METHODS: Using Swedish registries, we included all patients undergoing LAD-D1 bifurcation PCI with drug-eluting stents between 2010 and 2020. Patients were stratified into two groups: simple PC

Research on parapsychological (psi) phenomena is very relevant in the discussion of whether mental processes might go beyond the known limits of brain capacities. Nonetheless, most scientific and philosophical discussions of mind-brain relations do not even mention such research, despite showing similar empirical robustness to that of acknowledged mainstream research in psychology, medicine, and t

AIMS: Comparisons of international practice patterns and their impact on percutaneous coronary intervention (PCI) outcomes are lacking. We compared temporal PCI trends between Sweden and a large university hospital system in the US.METHODS AND RESULTS: Data within the Swedish Coronary Angiography and Angioplasty Registry (SCAAR) and the University of California San Diego Health internal National C

Pre-and postoperative photos to assess results are widely used in plastic and reconstructive surgery, for instance, in patients with cleft lip and palate (CL/P). Evaluations are often performed by assessment panels by viewing the photos. However, these are prone to be subjective. Measurements of soft tissues in photos could be an alternative method but have not been widely used so far. Some patien

In this study, we report on reactive large-eddy simulations (LESs) of flow and combustion in the U.S. Air Force Research Laboratory Research Cell 19 cavity-based scramjet combustor. This case involves the combustion of ethylene that is injected into a cavity. It has previously been studied experimentally with multiple techniques, including particle image velocimetry, hyperspectral imagining, and l

Denna studie syftade till att fördjupa förståelsen av hur personer inom ångest- och förstämningsspektrumen upplevde och tillskrev betydelse till Compassion Focused Therapy (CFT) som gruppbehandling i en svensk primärvårdskontext. Materialet utgjordes av 12 semistrukturerade intervjuer med deltagare som genomgått CFT-gruppterapi på en vårdcentral i södra Sverige. Genom reflexiv tematisk analys geneThis study aimed to deepen the understanding of how people within the anxiety and depression spectrums experienced and attributed meaning to Compassion Focused Therapy (CFT) as a group treatment in a Swedish primary care context. The material consisted of 12 semi-structured interviews with participants who had undergone CFT group therapy at a health center in southern Sweden. Through reflexive the

De senaste 20 åren har humanioraintegrering i professionsutbildning varit på frammarsch i Sverige, både som forskningsfält och högskolepedagogisk praktik. Detta syns bland annat på bildandet av ett antal tvärvetenskapliga centra och program med sådan integrering i fokus. Den akademiska litteraturen om humanioraintegration i professionsutbildning visar att utvecklingen i Sverige är en del av en int

The paper reports on preliminary findings from a case study of an autobiography-based course element included in the social work professional education program of a Swedish university. In the studied course element, the aim was for autobiographies to provide a platform and catalyst for student reflections on client perspectives as well as for reflexivity in relation to students’ own frames of refe

Research topic/aim:The purpose of this paper is to contribute empirically to the ongoing academic discussion about the meaningful implementation of narrative art as a pedagogical tool in professional ethics education (PEE). In the present work, meaningfulness is conceived of as connectedness, and narrative art includes literary fiction and autobiography. Research questions are:How do students in e

BACKGROUND: The REC-CAGEFREE trial showed that drug-coated balloons (DCB) did not achieve non-inferiority in the treatment of non-complex de novo lesion compared to a strategy of drug-eluting stents (DES). However, a prespecified subgroup analysis of arteries sized

We have investigated the adsorption of the amyloid-forming protein a-Synuclein (aSyn) onto small unilamellar vesicles composed of a mixture of zwitterionic POPC and anionic POPS lipids. aSyn monomers adsorb onto the anionic lipid vesicles where they adopt an a-helical secondary structure. The degree of adsorption depends on the fraction of anionic lipid in the mixed lipid membrane, but one needs t

This paper addresses the use of narrative in interdisciplinary professional education as a device for the reciprocal transfer of knowledge, insights, or methods between persons and knowledge domains, but also for their integration and transformation into burgeoning professional judgement. The paper considers an elective course for engineering students, in which emerging technology ethics are appro