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The ability to determine the myelin water fraction (MWF) in vivo is essential to assessments of neurodevelopmental myelination and myelin damage in neurodegenerative diseases. The analysis of multi-exponential T2 decay data relies on the non-negative-least-squares (NNLS) fitting, which may be sensitive to the chosen fitting parameters. We performed simulations to explore the outcomes of NNLS under

Wind is a complex phenomenon and a critical fac-tor in assessing climatic conditions and pedestrian comfortwithin cities. To obtain spatial information on near-groundwind speed, 3D computational fluid dynamics (CFD) model-ling is often used. This is a computationally intensive methodwhich requires extensive computer resources and is time con-suming. By using a simpler 2D method, larger areas can b

We used satellite remote sensing data; fractionof photosynthetically active radiation absorbed by vegetation(fPAR) from the Moderate Resolution Imaging Spectrora-diometer (MODIS) in combination with tower eddy covari-ance and meteorological measurements to characterise theLight Use Efficiency parameter (ε)variability and the maxi-mumε(εmax)for two contrasting Canadian peatlands. Eight-day MODISfPA

I språkutbildning vid svenska lärosäten finns det vanligtvis ett antal studenter i varje grupp som har det studerade språket som modersmål (L1), även om majoriteten utgörs av studerande som läser språket som främmande språk (L2). I vår studie undersöker vi erfarenheter av att undervisa denna typ av grupp genom semistrukturerade intervjuer med sex universitetslärare i franska, spanska och tyska. Un

Intravesical inoculation of gram negative bacteria or isolated bacterial products into mice induces an IL-6 response which can be measured within miutes of the infection.1,2 In such infections, IL-6 is initially detected in the urine and subsequently in the serum. Similar IL-6 responses were found in human patients deliberately colonized in the urinary tract with E. coli Hu7343. IL-6 was secreted

T-helper 2 (Th2) cell responses defend against parasites. Although dendritic cells (DCs) are vital for the induction of T-cell responses, the DC subpopulations that induce Th2 cells in the intestine are unidentified. Here we show that intestinal Th2 responses against Trichuris muris worms and Schistosoma mansoni eggs do not develop in mice with IRF-4-deficient DCs (IRF-4f/f CD11c-cre). Adoptive tr

Lymphocytes are the key cells of the adaptive immune system that provide antigen-specific responses tailored to the context of antigen exposure. Through cytokine release and antibody production, lymphocytes orchestrate and amplify the recruitment and function of other immune cells and contribute to host defense against invading pathogens and the pathogenesis of many inflammatory diseases. Lymphocy

Background: A slight increase in revisions for infected joint arthroplasties has been observed in the Nordic countries since 2000 for which the reasons are unclear. However, in 2007 a Swedish study of the timing for prophylactic antibiotics in a random sample of knee arthroplasties found that only 57% of the patients had received the antibiotic during the optimal time interval 45-15 minutes before

In Responsibility From the Margins, David Shoemaker distinguishes three forms of responsibility: attributability, answerability, and accountability. The introduction of various normative competence requirements lends precision to the contrasts that Shoemaker draws between these forms of responsibility. I argue, however, that these competence requirements are less well motivated than Shoemaker supp

The strongest constraint on Vtb presently comes from the 3 × 3 unitarity of the CKM matrix, which fixes Vtb to be very close to one. If unitarity is relaxed, current information from top production at Tevatron still leaves open the possibility that Vtb is sizably smaller than one. In minimal extensions of the standard model with extra heavy quarks, the unitarity constraints are much weaker, and th

We present the latest developments of the MadGraph/MadEvent Monte Carlo event generator and several applications to hadron collider physics. In the current version events at the parton, hadron and detector level can be generated directly from a web interface, for arbitrary processes in the Standard Model and in several physics scenarios beyond it (HEFT, MSSM, 2HDM). The most important additions ar

The ALICE Collaboration has measured the energy dependence of exclusive photoproduction of J / ψ vector mesons off proton targets in ultra–peripheral p–Pb collisions at a centre-of-mass energy per nucleon pair sNN=5.02 TeV. The e + e - and μ + μ - decay channels are used to measure the cross section as a function of the rapidity of the J / ψ in the range - 2.5 < y< 2.7 , corresponding to an energy

The new version of the MadGraph/MadEvent (MG/ME) MC generator is introduced by emphasizing its easy-to-use way of incorporating new models and generating events. As an application, a study of t t production in various scenarios beyond the standard model is presented.

We explore in detail the physics potential of a measurement of the t invariant mass distribution. First, we assess the accuracy of the best available predictions for this observable and find that in the low invariant mass region, the shape is very well predicted and could be used to perform a top mass measurement. Second, we study the effects of a heavy s-channel resonance on the t invariant mass

We present a consistent analysis of the signal as well as the irreducible background for the search of the SM Higgs boson in the ZZ decay channel at the LHC. Soft-gluons effects are resummed up to next-to-leading logarithmic accuracy, and the results are compared to those obtained with fixed order calculations and the MC@NLO event generator. The soft-gluon effects are typically modest but should b