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In both mice and humans alternate splicing results in isoforms of c-Kit characterized by the presence or the absence of a tetrapeptide sequence, GNNK, in the juxtamembrane region of the extracellular domain. Dramatic differences in the kinetics and magnitude of activation of the intrinsic tyrosine kinase activity of c-Kit between the GNNK and GNNK+ isoforms has previously been shown. Here we repor
Six species of Candelariella with polysporous asci are recognized from western North America. The species are: C. borealis sp. nov., C. efflorescens, C. lutella, C. placodizans, C. vitellina and C. xanthostigma. Candelariella vitellina is lectotypified. A key to the polysporous species in western North America is provided and their distribution in the study area is mapped.
Consider the Sobolev embedding operator from the space of functions in W-1,W-p(I) with average zero into L-p, where I is a finite interval and p > 1. This operator plays an important role in recent work. The operator norm and its approximation numbers in closed form are calculated. The closed form of the norm and approximation numbers of several similar Sobolev embedding operators on a finite inte
Triacylglycerol (TAG) is known to be synthesized in a reaction that uses acyl-CoA as acyl donor and diacylglycerol (DAG) as acceptor, and which is catalyzed by the enzyme acyl-CoA:diacylglycerol acyltransferase. We have found that some plants and yeast also have an acyl-CoA-independent mechanism for TAG synthesis, which uses phospholipids as acyl donors and DAG as acceptor. This reaction is cataly
For 10 consecutive winters, measurements were carried out in Lake Vendyurskoe, Karelia, Russia. The aim of these measurements was to investigate some of the physical processes in this small shallow lake during its ice-covered period. Detailed measurements of ice thickness and condition, snow thickness, water temperature, salt content, and currents were developed into a database. Within this databa
The role of the Laude g-factor in atomic spectroscopy is explored through theoretical studies for Ne I and Ne II where some experimental values are available. Extended correlation studies in the Breit-Pauli approximation for spectrum calculations are analysed and compared with experiment and other theory. For Ne II, the multiconfiguration Dirac-Hartree-Fock method was also applied, but correlation
OBJECTIVES: To study whether intrauterine growth restriction (IUGR) is associated with decreased sensitivity to the main fetal growth factor, insulin, and the effect of glucocorticoid therapy on insulin sensitivity in preterm infants. STUDY DESIGN: Newborn infants with a birth weight (BW) of< 1500 g were classified as appropriate for gestational age ([AGA], BW within +/- 1 SD, n = 10), or small fo
In pre-industrial Sweden (and other parts of' northwestern Europe) retirement arrangements were used by peasants to keep their property intact and to transfer it to one of the children while the other children were compensated with, for example, movable property or plots of land. In this article we study the frequency and form of this strategy in pre-industrial rural Sweden. While the literature o
Simultaneous saccharification and fermentation (SSF) of wood has been modeled for the past 15-20 years, but the substrates used for model evaluation have so far not included pretreated softwood. In the present study, data from lab-scale batch SSF of SO2-impregnated, steam-pretreated spruce chips were used to evaluate a model found in the literature. The model, which was somewhat modified, consists
Aims/hypothesis Events during fetal life may in critical time windows programme tissue development leading to organ dysfunction with potentially harmful consequences in adulthood such as diabetes. In rats, the beta cell mass of progeny from dams fed with a low-protein (LP) diet during gestation is decreased at birth and metabolic perturbation lasts through adulthood even though a normal diet is gi
1. High breeding density can cause elevated plasma androgen levels in adult birds. Since maternal androgens are deposited into egg yolk, high breeding density may result in elevated yolk androgen levels as well. 2. The relationship between breeding density and yolk androgen levels was examined in the European Starling, Sturnus vulgaris. The concentration and total content of yolk androstenedione a
The initial phase of inflammation in bronchial asthma appears to be triggered by the expression of leucocyte-endothelial adhesion molecules on endothelial cell surfaces. Cell adhesion molecules (CAMs) cause adhesion of leucocytes to the endothelium prior to their subsequent extravasation into inflamed tissue. We wanted to determine whether circulating intercellular adhesion molecule-1 (cICAM-1) an
Epithelial shedding occurs in health and, extensively, in inflammatory airway diseases. This study describes deepithelialisation, reepithelialisation and associated events in guinea-pig trachea after shedding-like epithelial denudation in vivo. Mechanical deepithelialisation of an 800-microns wide tracheal zone was carried out using an orotracheal steel probe without bleeding or damage to the base
The allocation and cycling of carbon (C) within forests is an important component of the biospheric C cycle, but is particularly understudied within tropical forests. We synthesise reported and unpublished results from three lowland rainforest sites in Amazonia (in the regions of Manaus, Tapajos and Caxiuana), all major sites of the Large-Scale Biosphere-Atmosphere Programme (LBA). We attempt a co
The effect of short-and long-term ethanol exposure on bradykinin-stimulated hydrolysis of phosphatidylinositol 4.5-bisphosphate (PIP2) was investigated in neuroblastoma X glioma hybrid cells (NG 108-15). Acute exposure of 50-150 mM ethanol neither influenced the bradykinin-stimulated accumulation of [3H]-inositol phosphates (IP1, IP2, IP3) nor the hydrolysis of PIP2 in cells labelled with [3H]-ino
Background: The relationship between atherothrombotic disease and venous thromboembolism (VTE) remains unclear. Patients and methods: In a cohort of 23 796 consecutive autopsies, performed using a standardized procedure and representing 84% of all in-hospital deaths between 1970 and 1982 in an urban Swedish population, we investigated the relationship between verified arterial thrombosis and VTE,
Nuclear quadrupole resonance (NQR) is a solid-state radio frequency (RF) spectroscopic technique that allows for the detection of many narcotics and highly explosive substances. Unfortunately, the practical use of NQR is often restricted by the presence of strong RF interference (RFI). In this letter, extending our recent work on stochastic NQR (sNQR), we propose acquiring signal-of-interest free
An integrated use of independent palaeoclimatological proxy techniques that reflect different components of the climate system provides a potential key for functional analysis of past climate changes. Here we report a 10,000 year quantitative record of annual mean temperature (T-ann), based on pollen-climate transfer functions and pollen-stratigraphical data from Lake Flarken, south-central Sweden
The authors investigated a possible contextual effect of neighborhood on individual use of hormone replacement therapy (HRT) and antihypertensive medication (AHM) and the impact of neighborhood social participation on individual use of these medications. They attempted to disentangle contextual from individual influences. Multilevel logistic regression modeling was used to analyze data on 15,456 w
