Interactions between staphylococci, heparin, heparin dependent growth factors and biomaterials
Popular Abstract in Swedish Användningen av konstgjorda material för temporärt och permanent bruk, t.ex katetrar, skruvar, ledproteser är numera väl etablerad inom human- medicinen. Dessa sk biomaterial kan emellertid predisponera till proppbildning, inflammatoriska vävnadsreaktioner och infektioner i omgivande vävnad, ledande till svåra komplikationer, såsom blod- förgiftning, passagestopp samt pResident skin micro-organisms such as S. epidermidis and other coagulase-negative staphylococci (CoNS), are by far the most common causes of biomaterial-associated infections. These micro-organisms often exhibit surface adhesins that specifically bind serum and tissue proteins adsorbed to implanted biomaterials. The aim of this study was to extend our knowledge about such adhesins produced by CoNS
