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We recently showed that lycopene inhibited lipopolysaccharide (LPS)-induced productions of nitric oxide (NO) and interleukin-6 (IL-6) in murine RAW264.7 macrophages by mechanisms related to inhibition of ERK and nuclear factor-kappa B. Since the assembly of Toll-like receptor 4 (TLR4) in lipid rafts is a key element in LPS induced signaling, we investigated whether this process would be influenced

A detailed investigation of aluminum plasma induced by a 1064 nm Nd:YAG laser in air was performed. The emission of spectral lines arising from Al I transition at 396.07 nm, Al II transition at 358.46 nm, Al Ill transition at 360.72 nm and Al IV transition at 363.05 nm were well-resolved. The plasma parameters including electron temperature and electron density were determined through the Boltzman

A tracking problem for a mechanical system is considered. We start with a feedback controller that is designed without attention to disturbances, which are assumed to be adequately described by a dynamic LuGre friction model. We are interested in deriving a superimposed observer-based compensator to annihilate or reduce the influence of such a disturbance. We exploit a recently suggested approach

Objective and methods A member of the major human cytochrome P450 superfamily of hemoproteins, CYP3A4/5, converts cholesterol into 4 beta-hydroxycholesterol. We studied plasma 4 beta-hydroxycholesterol levels prior to and 4 weeks after initiating antiretroviral therapy that included efavirenz, ritonavir-boosted atazanavir or ritonavir-boosted lopinavir with the aim of exploring the usefulness of p

Partial ion yield spectroscopy was used to study fragmentation processes in cyanogen after C 1s and N 1s photoexcitation. The interpretation of the core excitation spectrum mostly follows the literature, but the high resolution has in some cases allowed a more detailed assignment. Using the fact that in Rydberg states there is an intensity increase as the fragmentation process becomes more extensi

The management of primary gastrointestinal stromal tumours (GISTs) has evolved with the introduction of adjuvant therapy. Recently reported results of the SSG XVIII/AIO trial by the Scandinavian Sarcoma Group (SSG) and the German Working Group on Medical Oncology (AIO) represent a significant change in the evidence for adjuvant therapy duration. The objectives of this European Expert Panel meeting

In 1996 there was no convincing laboratory evidence that EMFs used in wireless communication could cause tumour promotion at non-thermal exposure levels. Therefore we then performed a study of the effects from exposure to such electromagnetic fields in the rat brain glioma model we were using in our research for brain tumour therapy. By stereotaxic technique rat glioma cells (RG2 or N32) were inje

In this article, we draw on a postcolonial sensibility to deconstruct how culture is discussed in mainstream international business textbooks. Through this deconstruction we show: (1) how the initial disclaimers that call for cultural sensitivity can be seen as pointing to the opposite of what they claim, which leads us to question the cultural sensitivity notion from ethical and political standpo

We report lifetime measurements of the five levels in the 3d(4)(a(5)D)5s e(6)D term in Cr II at an energy around 83 000 cm(-1), and log(gf) values for 38 transitions from the investigated levels. The lifetimes are obtained using time-resolved, laser-induced fluorescence on ions from a laser-produced plasma. Since the levels have the same parity as the low-lying states directly populated in the pla

Objectives: Patients with type 1 diabetes mellitus (T1DM) lack the portal/peripheral insulin gradient, which might diminish insulin stimulation of hepatic lipogenesis and protect against development of nonalcoholic fatty liver disease (NAFLD). We compared liver fat content and insulin sensitivity of hepatic glucose production and lipolysis between overweight T1DM patients and nondiabetic subjects.

Vi väntar oss att konstnärer ska vara kreativa, men erfarna konstnärer är framför allt hantverksskickliga. I allmänhet är konstnärer inte mer kreativa än andra människor. De kompletterar en tradition eller etablerad teoribildning, precis som forskare. Men till skillnad mot forskare som har ett väldefinierat problem med en given om än okänd lösning via en föreskriven metod, arbetar konstnären med ö

Säkerhet är dynamiskt och speciellt så i komplexa säkerhetskritiska verksamheter. När olyckor och incidenter är sällan förekommande i säkerhetskritiska verksamheter kan det ske en långsam och naturlig erosion av säkerhetsmedvetandet och en organisations beteenden kan börja driva mot säkerhetsmarginalerna. Säkerhetskulturen ses som en stark motriktad kraft i ett sådant händelseförlopp. Att organisa

Mixed findings have been made with regard to the long-term predictive validity of antisocial personality disorder (ASPD) on criminal behaviour in samples of substance abusers. A longitudinal record-linkage study of a cohort of 1052 drug abusers admitted 1977-1995 was undertaken. Subjects were recruited from a detoxification and short-term rehabilitation unit in Lund, Sweden, and followed through c

The article provides with an overview over female sociability in eighteenth century Sweden.

Review of the book Arkeologi i förorten. Berättelser från norra Botkyrka (ed.) Mats Burström

Von Willebrand factor (VWF) is an abundant plasma glycoprotein involved in platelet adhesion and aggregation at sites of vascular injury. ADAMTS13 is the sole physiological VWF-cleaving protease, thus regulating the size of thrombus growth. Dysfunctional ADAMTS13 leads to thrombotic thrombocytopenic purpura (TTP), which is either due to mutations (congenital TTP) or auto-antibodies (acquired TTP).