In 2018, up to 4 million m3 Norway spruce was killed by the spruce bark beetle Ips typographus in Sweden. The event was unique for Sweden, in terms of both affected volume and the fact that it was triggered by severe drought stress, not by ample availability of relatively defenseless storm-felled trees. The outbreak continued in 2019 and 2020, each year with twice as many trees killed as in 2018.

The conterminous marine system of the Bering Sea serves as an important connection between the Pacific and the Arctic. Surface water temperatures of the Northern Pacific have been rising over the past decades with associated changes in extremes: marine heatwaves (MHWs). This study aims to explore the spatiotemporal evolution characteristics and occurrence mechanisms of MHWs in the Bering Sea. Our

Renovation at district scale is a key strategy to reduce CO2 emissions by optimising the implementation of renewable energy sources and taking advantage of economy of scale. This paper focuses on analysing good practice examples on energy renovations at district scale. The paper adapts a qualitative research methodology in four phases, including the multi-perspective analysis of nine exemplary ren

The interpretation of reflexive pronouns has been the topic of extensive linguistic research. This paper illustrates how different types of reflexive pronouns can be inter-preted and generated within the framework of Referent Grammar, a grammar which can be run directly on the computer. The rules illustrated are to be used in the machine translation project SWETRA which translates between English,

Coordinated structures are very frequent in texts, but generally grammatical theories have little to say on the subject. This paper describes the different types of coordination and shows how they can be analyzed - and understood - using Prolog. The work has been carried out within the automatic translation project SWETRA (Sigurd & Gawroriska-Wemgren 1988).

Dissemination of Bacillus anthracis from the respiratory mucosa is a critical step in the establishment of inhalational anthrax. Recent in vitro and in vivo studies indicated that this organism was able to penetrate the lung epithelium by directly entering into epithelial cells of the lung; however the molecular details of B. anthracis breaching the epithelium were lacking. Here, using a combinati

Heparan sulfate (HS) interacts with a variety of proteins and thus mediates numerous complex biological processes. These interactions critically depend on the patterns of O-sulfate groups within the HS chains that determine binding sites for proteins. In particular the distribution of 6-O-sulfated glucosamine residues influences binding and activity of HS-dependent signaling molecules. The protein

Heparan sulfate mediates numerous complex biological processes. Its action critically depends on the amount and the positions of O-sulfate groups (iduronyl 2-O-sulfates, glucosaminyl 6-O- and 3-O-sulfates) that form binding sites for proteins. The structures and distribution of these protein-binding domains are influenced by the expression and substrate specificity of heparan sulfate biosynthetic

Glycosaminoglycan heparan sulphate interacts with a variety of proteins, such as growth factors, cytokines, enzymes and inhibitors and, thus, influences cellular functions, including adhesion, motility, differentiation and morphogenesis. The interactions generally involve saccharide domains in heparan sulphate chains, with precisely located O-sulphate groups. The 6-O-sulphate groups on glucosamine

Introduction Episodic memory allows us to revisit our past and recollect inter-related elements that characterize life events (Tulving, 1983). When forming such relational memories, we only apprehend a small part of our visual field in full acuity at a time. This limitation is overcome by shifting visual attention over a sequence of eye movements. We bind these visual “samples” of the world into

Prevotella copri DSM18205T is a human gut bacterium, suggested as a next-generation probiotic. To utilize it as such, it is, however, necessary to grow the species in a reproducible manner. Prevotella copri has previously been reported to be highly sensitive to oxygen, and hence difficult to isolate and cultivate. This study presents successful batch cultivation strategies for viable strain inocul

Prevotella copri is a bacterium that can be found in the human gastrointestinal tract (GIT). The role of P. copri in the GIT is unclear, and elevated numbers of the microbe have been reported both in dietary fiber-induced improvement in glucose metabolism but also in conjunction with certain inflammatory conditions. These findings raised our interest in investigating the possibility of P. copri to

The Virus-X-Viral Metagenomics for Innovation Value-project was a scientific expedition to explore and exploit uncharted territory of genetic diversity in extreme natural environments such as geothermal hot springs and deep-sea ocean ecosystems. Specifically, the project was set to analyse and exploit viral metagenomes with the ultimate goal of developing new gene products with high innovation val

Much contemporary critical infrastructure research has been devoted to studies of the effects of risks stemming from interdependencies between critical infrastructures, here referred to as interdependency-related risks. However, this research has placed limited emphasis on infrastructure actors’ efforts to manage such risks in practice, and it remains unclear to what extent and how critical infras

Falling pitch has long been argued to be a key feature in the distinction of Swedish pitch accents. In this paper, neurophysiological and behavioural evidence substantiating the perceptual importance of HL pitch contours at the word level is discussed. When presentedwith novel words, Swedes, regard-less of dialect,preattentively distinguished meaningfulwords with falling pitch.Falling pitch was al