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Statin use and risk of depression: a Swedish national cohort study
Background: Statin medications, used to prevent heart disease by reducing cholesterol, also reduce inflammation and protect against oxidative damage. As inflammation and oxidative stress occur in depression, there is interest in their potential to reduce depression risk. We investigated whether use of statin medications was associated with a change in the risk of developing depression in a very la
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Neutron guide-split: A high performance guide bundle concept for elliptical guides
We present a new guide-split concept for transporting cold and thermal neutrons to multiple instruments from a single beam port at a neutron facility without compromising the useful neutron brilliance notably for any of the instruments. Elliptical guides are capable of transporting an almost completely filled phase space within a large divergence (+/- 2 degrees for cold neutrons). It is therefore
Review of Karin Tegenborg Falkdalen, "Vasadöttrarna"
The Columnar Lined Esophagus: aspects on the assessment of dysplasia and on the relationship with the esophageal submucosal glands
Columnar metaplasia, where columnar epithelium replaces the normal squamous epithelium in esophagus, is considered to be a precancerous condition in which the development of adenocarcinoma can be followed through various grades of dysplasia. The interpretation of these histological changes is subjective and suffers from considerable inter-observer variation among pathologists. In study I, we devis
Paradiset : ökenfädernas tänkespråk : den systematiska samlingen. 1. De heliga fädernas råd för den som söker fullkomlighet
Changes in self and object representations following psychotherapy measured by a theory-free, computational, semantic space method
We propose a theory-neutral, computational and data-driven method for assessing changes in semantic content of object representations following long-term psychodynamic psychotherapy. Young adults in psychotherapy are compared with an age-matched, non- clinical sample at three time points. Verbatim transcripts of descriptions of the self and parents were quantified in a semantic space constructed b
Resource allocation and disturbance rejection in web servers using SLAs and virtualized servers
Abstract—Resource management in IT–enterprises gain more and more attention due to high operation costs. For instance, web sites are subject to very changing traffic–loads over the year, over the day, or even over the minute. Online adaption to the changing environment is one way to reduce losses in the operation. Control systems based on feedback provide methods for such adaption, but is in natur
Responses to Tumour initiating factors and Regulation of Normal and Malignant Haematopoiesis
The haematopoietic stem cell (HSC) resides within a specific environment enabling it to retain its self-renewal capacity or quiescent state. It is proposed that the HSC niche is hypoxic, a milieu within which the HSC is protected from intrinsic and extrinsic stimuli. We have investigated the haematopoietic phenotype of an HSC in a mouse model where hypoxia-regulated Vegfa expression is abrogated.
Long Term Efficacy And Tolerability Of Anagrelide In Myeloproliferative Disorders
Patterns of Post-Glacial Genetic Differentiation in Marginal Populations of a Marine Microalga
This study investigates the genetic structure of an eukaryotic microorganism, the toxic dinoflagellate Alexandrium ostenfeldii, from the Baltic Sea, a geologically young and ecologically marginal brackish water estuary which is predicted to support evolution of distinct, genetically impoverished lineages of marine macroorganisms. Analyses of the internal transcribed spacer (ITS) sequences and Ampl
Physiological state of female and light intensity affect the host-plant selection of carrot psyllid, Trioza apicalis (Hemiptera : Triozidae)
We have studied the effect of different light gradient regimes on host-plant selection of the carrot psyllid, Trioza apicalis Forster. In both a strong and a weak light gradient, carrot psyllids preferred a carrot leaf placed in higher light intensity. When the choice was between the host (carrot Daucus carota L.) and a non-host (barley Hordeum vulgare L.) virgin adults settled significantly more
Who decides the position for birth? A follow-up study of a randomised controlled trial
Background: Physical benefits are suggested for women and their babies when women adopt an upright position of their choice at birth. Available care options during labour influence women's impressions of what intrapartum care is. This indicates that choice of birth positions may be determined more by midwives than by women's preferences. Question: The aims of this study were to investigate factors
Changes in Membrane Phospholipids as a Mechanistic Explanation for Decreased Freeze Tolerance in Earthworms Exposed to Sublethal Copper Concentrations
At low temperature, cell membrane functionality depends on adjustments of membrane phospholipid fatty acid (PLFA) composition. We here test the hypothesis that previous exposure to copper (Cu) may deteriorate tolerance to freezing temperatures because of Cu-induced changes of PLFA composition of cell membranes in the freeze-tolerant earthworm Dendrobaena octaedra. Cu levels and freezing temperatur
Influence of glutathione-related genes on symptoms and immunologic markers among vulcanization workers in the southern Sweden rubber industries.
OBJECTIVE: The aim was to elucidate the role of genetic variants on symptoms of the eyes and airways, headache and nausea, as well as on immunologic markers, among vulcanization workers in the contemporary Swedish rubber industry. Polymorphisms in genes, which are involved in the defense against reactive oxygen species and metabolism of toxic substances present in the vulcanization fumes, were ana
Turning waste into value: using human urine to enrich soils for sustainable food production in Uganda
This article builds on an action research process involving Ugandan smallholder farmers in collaborative experimentation on the use of human urine as a crop fertilizer. The aim is to explore farmers' perceptions and evaluation of the practice as a potential and partial solution to soil productivity problems. Findings show that urine fertilization is valued as a low-cost and low-risk practice contr
Lighting control systems in individual offices at high latitude: measurements of lighting conditions and electricity savings
An efficient lighting control systems (LCS) should take advantage of the natural light available, but this presents some technical challenges as well as user related issues. So far, the assessment of lighting energy consumption of LCS has been based on technical features rather than the occupants’ acceptance. This article presents the results of a monitoring study providing some recommendations ba
Visualizing Interfacial Charge Transfer in Ru-Dye-Sensitized TiO2 Nanoparticles Using X-ray Transient Absorption Spectroscopy
A molecular level understanding of the structural reorganization accompanying interfacial electron transfer is important for rational design of solar cells. Here we have applied XTA (X-ray transient absorption) spectroscopy to study transient structures in a heterogeneous interfacial system mimicking the charge separation process in dye-sensitized solar cell (DSSC) with Ru(dcbpy)(2)(NCS)(2) (RuN3)
Pleiotropic Effects of GIP on Islet Function Involve Osteopontin
OBJECTIVE-The incretin hormone GIP (glucose-dependent insulinotropic polypeptide) promotes pancreatic beta-cell function by potentiating insulin secretion and beta-cell proliferation. Recently, a combined analysis of several genome-wide association studies (Meta-analysis of Glucose and Insulin-Related Traits Consortium [MAGIC]) showed association to postprandial insulin at the GIP receptor (GIPR)