PLK-1 inhibition has a functional impact on MYC and is a relevant target for high-risk mantle cell lymphoma patients
types of B-cell lymphomas. However, the role of MYC in mantle cell lymphoma (MCL), a clinically diverse and incurable disease, needs to be further elucidated. The aim of this study is to evaluate MYC mRNA deregulation and explore the mechanism behind PLK-1 induced cell death, as a target for MYC-driven MCL. To achieve this, RNAscope® is used to detect and quantify MYC mRNA expression in a populati
