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There are an increasing number of genetic and neuropathological observations to suggest that cystatin C, an extracellular protein produced by all nucleated cells, might play a role in the pathophysiology of sporadic Alzheimer's disease (AD). Recent observations indicate that small and large soluble oligomers of the beta-amyloid protein (A beta) impair synaptic plasticity and induce neurotoxicity i
We trace the difference between the ways in which apes and humans co–operate to differences in communicative abilities, claiming that the pressure for future–directed co–operation was a major force behind the evolution of language. Competitive co–operation concerns goals that are present in the environment and have stable values. It relies on either signalling or joint attention. Future–directed c
To study whether antibodies to glutamic acid decarboxylase (GADab) are associated with subclinical beta-cell damage and impaired insulin secretion, we screened 441 nondiabetic patients with autoimmune thyroiditis (AT) for GADab, and 15 (3.4%) were found positive. Antibodies to IA-2 were found in two GADab+ and one GADab- patients. We matched 11 GADab+ and 13 GADab- AT patients who were euthyroid o
Box jellyfish, or cubomedusae, possess an impressive total of 24 eyes of four morphologically different types. Compared to other cnidarians they also have an elaborate behavioral repertoire, which for a large part seems to be visually guided. Two of the four types of cubomedusean eyes, called the upper and the lower lens eye, are camera type eyes with spherical fish-like lenses. Here we explore th
Thidevalls avhandling i kyrkohistoria utgår från Svenska kyrkans möte med det moderna samhället. Hypotesen är att Svenska kyrkan fick sina strukturer präglade av andra intressen än biskopsmotionens reformprogram 1929. Detta program sätts in i sin kyrkopolitiska närkontext med nya kommunallagar, församlingsstyrelselag, Kungl. Maj:ts beslut att ge Lilla katekesen större utrymme i folkskolan, och öve
Time-resolved laser-induced fluorescence measurements have been performed for ten odd Rydberg states of neutral lutetium, belonging to the 6s(2)(S-1)np(n = 8-9) and 6 s(2)(S-1)nf (n = 5-8) series. For 6S(2)(S-1)8p and 6s(2)(S-1)7f, the experimental lifetimes corresponding to the two J values within the doublet differ substantially. Comparison with theoretical values, calculated with extensive conf
Popular Abstract in Swedish I denna avhandling har jag undersökt hur man kan utöka det dynamiska omfånget utan att öka noggrannheten i en analog-till-digital omvandlare med en flyttalsliknande lösning. Den valda lösningen går ut på att man förstärker en analog insignal med flera oberoende analoga förstärkare med skilda förstärkningar. Sedan väljs den förstärkare som ger den starkaste utsignalen sTo deal with the wide dynamic rage necessary for a radio receiver or corresponding applications, but to avoid impractically high resolution at high data rates, the approach of using a floating-point analog-to-digital converter (FP-ADC) has been investigated. This approach de-links the dynamic range with the resolution, and a very wide dynamic range can be achieved by an ADC with a moderate resolut
An account of the importance of the photographic documentation of the Nazi concentration camps for the reaction to and understanding of Nazism and the Holocaust.
In this paper we analyse an extremum controller based on a pulsetechnique. The idea is to superimpose probing pulses to the controlsignal and use for feedback the size of the pulse response in the output. Theprobing control strategy has been used with success forthe control of the substrate feeding in E. coli cultivations. The analysis is done here for systems ofHammerstein type with a piecewise a
W(+)W(-)gamma production at LEP2 is studied using data collected with the DELPHI detector at centre-of-mass energies between 189 GeV and 209 GeV, corresponding to an integrated luminosity of about 600 pb(-1). Cross-sections are measured for the production of W+W- with a hard, central and isolated photon in the final state, and are found to be compatible with the Standard Model prediction. The phot
Let X-1, X-2,... be independent and symmetric random variables such that S-n = X-1+...+ X-n converges to a finite valued random variable S a. s. and let S* = sup(1 <= n
