Filtyp
Introduction: Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) may cause stress-induced transient acute cardiac dysfunction through myocardial stunning, in the form of exacerbation-triggered Takotsubo syndrome (referred to as Takotsubo stunning). Although prior studies suggest an association between AECOPD and transient cardiac dysfunction, existing evidence is limited to retro
The rapid adoption of electric vehicles (EVs) with increasingly advanced battery technologies is reshaping electricity demand patterns. Yet existing studies often assume static behaviors, overlooking that real-world charging patterns are transient and evolve in response to technological change. This study applies a scenario-aware generative modeling framework to project weekly EV charging demand i
With growing interest in cobalt-based complexes for electrocatalytic applications, we synthesized four homoleptic facial-octahedral Co(iii) β-oxodithioester complexes (1–4) with the general composition [Co(L)3], where L represents 3-(methylthio)-1-(furan-2-yl)-3-thioxoprop-1-en-1-olate (L1), 3-(methylthio)-1-(thiophen-2-yl)-3-thioxoprop-1-en-1-olate (L2), 3-(methylthio)-1-(pyridin-3-yl)-3-thioxopr
Cross-linguistic research shows that languages differ in how they encode the basic semantic components of motion events (figure, motion, manner, path, and ground) in their grammars and lexicons. While manner and path encoding have received significant attention, one core component has been underestimated: ground, the object or surface relative to which motion occurs. In fact, the possibility of gr
We present MixtureVitae, an open-access pretraining corpus1 built to minimize legal risk while providing strong downstream performance. MixtureVitae follows a permissive-first, risk-mitigated sourcing strategy that combines public-domain and permissively licensed text (e.g., CC-BY/Apache) with carefully justified low-risk additions (e.g., government works and EU TDM-eligible sources). MixtureVitae
Objective: To describe the epidemiology of injuries and illnesses at the Paris 2024 Paralympic Games. Methods: Injuries and illnesses were recorded daily via a web-based injury and illness surveillance system and local organising committee medical facilities. Adjusted incidences (injuries/illnesses per 1000 athlete days; 95% CIs), injury prevalence (IP; %) and injury burden (days lost per 1000 ath
Myostatin negatively regulates skeletal muscle size in multiple species, and therefore, myostatin blockade has been therapeutically explored to promote muscle growth in humans, including to counter the muscle loss seen in obese humans using GLP1R agonists. In this study, we present results from a large multi-cohort genetic association analysis, using data from 1.1 million individuals to examine th
Previous experimental studies of pyrrole pyrolysis reported numerous hydrocarbon and nitrogen-containing products from HCN up to pyridine and dinitriles. To develop a consistent detailed kinetic mechanism for pyrrole, the rate constants of H atom abstraction from C4H5N by NH2, and CH2CN radicals have been calculated at the DLPNO-CCSD(T)-F12/cc-pVDZ-F12//M06–2X/def2-TZVP level of theory while H ato
Background and purpose: Claudin-5 plays a crucial role in maintaining blood-brain barrier (BBB) integrity through endothelial tight junction formation. Alternative splicing of claudin-5 within the microvascular endothelium may modulate BBB structural and functional dynamics, thereby affecting neuronal damage and recovery after ischemic stroke. The aim of this study was to investigate temporal and
This working paper examines Sweden’s Covid-19 vaccine procurement and distribution strategy as part of the SCANVAX project on Nordic vaccine diplomacy. Drawing primarily on a review of news media, parliamentary records, government reports and other documentary sources, the study analyses how Sweden worked to procure Covid-19 vaccines to cover the needs of Swedish residents, as well as how Sweden e
This volume explores the poetic and philosophical boundaries between humanity and divinity across the Hebrew Bible, Graeco-Roman literature, and early Christian thought. Inspired by Psalm 8 and the verses of Sappho and Catullus, the title evokes the ancient tension between being human and “almost divine.”Essays by leading scholars examine prophetic transmission, divine legitimization of power, asc
In this paper we critically assess common perceptions of work to inform current debates on work in ecological economics. Work is usually conceived as (1) a productive activity (2) that satisfies consumer demand, (3) is conducive to health and well-being, and (4) ensures social inclusion and personal development. Drawing on the burgeoning literature of postwork or critiques of work, we argue that w
In diesem essential werden die aktuellen Probleme der Agenda 2030 zur Umsetzung der Nachhaltigkeitsziele im Bereich Gesundheit erläutert. Das weltweite Aufkommen von Zivilisationskrankheiten und die explodierenden Kosten in der medizinischen Versorgung stellen die Weltgemeinschaft in Zeiten von Corona und Krieg vor große Herausforderungen. Um einen weiteren Rückschritt in der globalen Gesundheitsv
Die Agenda 2030 hat sich zum Ziel gesetzt, eine Welt ohne Armut, Hunger und Krankheit zu schaffen und dafür zu sorgen, dass jeder Mensch ein Leben frei von Furcht und ohne Unterdrückung führen kann. Um dies zu erreichen, muss jeder Mensch auch ein Recht auf Bildung haben. Ganzheitliche Bildungskonzepte sind hierbei von großer Bedeutung, da mit ihnen ein Umdenken zu einer nachhaltigen Lebensweise i
In der Geschichte der Menschheit haben Seuchen und Plagen immer wieder eine Spur von Leid und Tod hinterlassen. Auch in der Zukunft werden wir nicht von Pandemien, die über uns hereinbrechen werden, verschont bleiben. Der Ausbruch von COVID-19 kann daher auch als der Beginn einer neuen Bedrohung, die von lebensgefährlichen Infektionskrankheiten ausgeht, angesehen werden. Ursache hierfür sind unter
