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How do dementia diseases affect our brains?

By Pia [dot] romare [at] fsi [dot] lu [dot] se (Pia Romare) - published on 23 August 2018“We must understand the ageing process itself in order to help people with conditions such as Alzheimer’s and dementia, and to possibly enable us to prevent these diseases from arising”, says Henrik Ahlenius of the Stem Cell Centre at Lund University. His aim is to develop an experimental model for human nerve

https://www.stemcellcenter.lu.se/article/how-do-dementia-diseases-affect-our-brains - 2025-10-05

Prestigious scientific prize awarded to Director of Lund Stem Cell Center

Zaal Kokaia, Professor within the Department of Clinical Sciences and Director of Lund Stem Cell Center, has been awarded Georgia’s most prestigious scientific prize - the National Prize in Science.  The award comes as a result of his outstanding contribution to world class scientific research and was presented to Prof. Kokaia at a ceremony in the Presidential Palace, Tbilisi, by the Georgian Pres

https://www.stemcellcenter.lu.se/article/prestigious-scientific-prize-awarded-director-lund-stem-cell-center - 2025-10-05

Thesis Defence Interview - Margarita Chumarina

Margarita Chumarina, from the iPSC laboratory for CNS disease modeling, will be defending her PhD thesis on Wednesday 15th of January. Researching in the group led by Laurent Roybon, Margarita has been utilizing stem cell-based models to study cellular alterations in Parkinson’s disease. Here, Margarita answers a few questions about her research and time spent at Lund Stem Cell Center. What have y

https://www.stemcellcenter.lu.se/article/thesis-defence-interview-margarita-chumarina - 2025-10-05

Thesis Defence Interview - Sara Nolbrant

Sara Nolbrant, from the Developmental and Regenerative Neurobiology lab, will be defending her PhD thesis on Friday 31st of January. Researching in the group led by Malin Parmar, Sara has been directing and dissecting the fate of dopaminergic neurons with the aim developing cell replacement therapy for the treatment of Parkinson’s disease. Here, Sara answers a few questions about her research and

https://www.stemcellcenter.lu.se/article/thesis-defence-interview-sara-nolbrant - 2025-10-05

Two new principal investigators at Lund Stem Cell Center

We are very happy to announce that two new PIs have joined Lund Stem Cell Center! Björn Nilsson is Professor of Clinical Immunology at the Medical Faculty of Lund University, and the Head of the Division of Hematology and Transfusion Medicine at the Department of Laboratory Medicine. He is also a visiting researcher at the Broad Institute (Cambridge, MA) and now a member of Lund Stem Cell Center.T

https://www.stemcellcenter.lu.se/article/two-new-principal-investigators-lund-stem-cell-center - 2025-10-05

The world's largest stem cell biobank launched

Diabetes, cardiovascular disease, Parkinson's and Alzheimer's disease make up the world’s most common diseases. A new biobank at Lund University in Sweden - the largest of its kind - with stem cells from both those affected and healthy individuals, will contribute to an increased understanding of how these diseases arise. “The goal is for researchers to be able to develop new treatments that can p

https://www.stemcellcenter.lu.se/article/worlds-largest-stem-cell-biobank-launched-0 - 2025-10-05

Continued interest in stem cells among high school students

High school students from all over the Skåne region will be visiting Lund University to spend a whole day discussing the current state of stem cell research, discovering what it is like to work in a research setting, and exploring the exciting future possibilities that stem cells have to offer. Building on the success of the previous five years, Lund Stem Cell Center is hosting UniStem Day March 6

https://www.stemcellcenter.lu.se/article/continued-interest-stem-cells-among-high-school-students - 2025-10-05

PI Agnete Kirkeby returns to Lund Stem Cell Center

Wallenberg Molecular Medicine Fellow Agnete Kirkeby has re-established her research group at Lund Stem Cell Center. With labs situated at both Lund and at the Department of Neuroscience at Copenhagen University, Agnete’s aim is to develop stem cell-based neural cell therapies to replace lost neurons as a treatment for brain diseases. As a main project, the Kirkeby research groups focus is on the d

https://www.stemcellcenter.lu.se/article/pi-agnete-kirkeby-returns-lund-stem-cell-center - 2025-10-05

Lund Stem Cell Center Image Competition 2020

Lund Stem Cell Center employees and students are hereby invited to enter the Image Competition 2020! We want inspirational images that capture the spirit of Lund Stem Cell Center. Any research related images will be accepted. Not just pictures of cells or sections, it could be your work environment, equipment, imaging, laboratory researchers, it’s up to you! We want to showcase the amazing researc

https://www.stemcellcenter.lu.se/article/lund-stem-cell-center-image-competition-2020 - 2025-10-05

Bringing stem cell research to the next generation of scientists

UniStem Day 2020 was another great success, with high school students visiting Lund University to enjoy a variety of activities introducing them to the fascinating world of stem cell research. The 6th UniStem day hosted by Lund University kicked off at the LUX Aula lecture theatre, Lund University, where over 200 high school students from over the Skåne region were welcomed by event co-ordinator A

https://www.stemcellcenter.lu.se/article/bringing-stem-cell-research-next-generation-scientists - 2025-10-05

Scientists repair stroke-damaged rat brain

Researchers from Lund University have now succeeded in restoring mobility and sensation in rats that have suffered Stroke, by transplanting neurons developed from reprogrammed human skin cells into animal brains. “Six months after transplant, we could see how the new cells had repaired the damage that a stroke had caused in the brains of rats," explains Professor Zaal Kokaia, who together with sen

https://www.stemcellcenter.lu.se/article/scientists-repair-stroke-damaged-rat-brain-1 - 2025-10-05

Thesis Defence Interview – Daniela Grassi

With a research focus on the development and application of in vitro models to study human brain evolution and disease, PhD student Daniela Grassi will be defending her thesis on Thursday 23rd of April 2020. Here, Daniela tells us about her research in the Molecular Neurogenetics group, led by Johan Jakobsson, and her time spent at Lund Stem Cell Center. Can you tell us about your research?During

https://www.stemcellcenter.lu.se/article/thesis-defence-interview-daniela-grassi - 2025-10-05

Thesis Defence Interview – Carla Azevedo

Carla Azevedo is set to defend her PhD thesis titled “Oligodendroglial (dys)function in alpha-synucleinopathies” on Thursday 30th of April. Here, Carla answers a few questions about her PhD journey at Lund Stem Cell Center, researching in the iPSC Laboratory for CNS disease modeling. How did you end up doing a PhD at Lund Stem Cell Center?I’m originally from Porto, Portugal. After my undergraduate

https://www.stemcellcenter.lu.se/article/thesis-defence-interview-carla-azevedo - 2025-10-05

Autophagy and the treatment of Huntington disease: timing is key

Huntington disease is fatal inherited brain disorder, usually emerging during mid-life. Although there is currently no known cure, the Molecular Neurogenetics group at Lund Stem Cell Center aims to understand the defective cellular processes leading to the progression of this disease. Characterised by symptoms including impaired motor and cognitive function, Huntington disease is caused by the exp

https://www.stemcellcenter.lu.se/article/autophagy-and-treatment-huntington-disease-timing-key - 2025-10-05

New method provides unique insight into the development of the human brain

Stem cell researchers at Lund University in Sweden have developed a new research model of the early embryonic brain. The aim of the model is to study the very earliest stages of brain to understand how different regions in the brain are formed during embryonic development. With this new insight, researchers hope to be able to produce different types of neural cells for the treatment of neurologica

https://www.stemcellcenter.lu.se/article/new-method-provides-unique-insight-development-human-brain - 2025-10-05

Researchers identify a novel regulator of neurogenesis in the aged brain

Neurogenesis, the process by which new neurons are formed, dramatically declines in the aging brain. A research group from Lund Stem Cell Center have published a study that sheds light on the different factors contributing to this loss, particularly the role of inflammation. “One of the focuses of our research is on what goes wrong in the brain during aging” explains Henrik Ahlenius, principle inv

https://www.stemcellcenter.lu.se/article/researchers-identify-novel-regulator-neurogenesis-aged-brain - 2025-10-05

Thesis Defence Interview – Franziska Olm

PhD student Franziska Olm has been developing a microfluidic-based acoustophoresis method to process stem cell preparations label-free, a technique with great research and clinical potential. In this interview, Franziska tells us about her PhD project, her time at Lund Stem Cell Center and her plans following her thesis defence on Friday June 12th 2020. Can you tell us about your research?Complex

https://www.stemcellcenter.lu.se/article/thesis-defence-interview-franziska-olm - 2025-10-05

New insights into the ex vivo expansion of transplantable human blood stem cells

Researchers from Lund Stem Cell Center have identified a novel target for the expansion of human blood stem cells ex vivo and shed light on the mechanism of action of a stem cell promoting molecule, currently in phase II clinical trials. Hematopoietic stem cell transplantation is a curative therapy for many patients suffering from life threatening blood disorders. This treatment is currently limit

https://www.stemcellcenter.lu.se/article/new-insights-ex-vivo-expansion-transplantable-human-blood-stem-cells - 2025-10-05

Nanostraws used to deliver biomolecules to stem cells

Researchers from Lund University have developed a promising new method for delivering biomolecules into human blood stem cells using nanotechnology. With little to no detrimental effects on target cells, this novel approach has great potential for research and clinical applications. The discovery and development of therapeutic biomolecules - such as the gene editing technology CRISPR - has rapidly

https://www.stemcellcenter.lu.se/article/nanostraws-used-deliver-biomolecules-stem-cells - 2025-10-05

Striking research images decorate Lund Biomedical Center

Those who find themselves at Lund BMC can now discover exciting new artwork highlighting the visual side of research. Created by researchers from the Faculty of Medicine, these images were part of ‘The invisible body – art in science’ exhibition held in Stockholm. Here, Christine Karlsson - director of the Research School in Stem Cell Biology at Lund Stem Cell Centre - provides us with more inform

https://www.stemcellcenter.lu.se/article/striking-research-images-decorate-lund-biomedical-center - 2025-10-05