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Selective Sorbents - Silica-immobilized affinity ligands and molecularly imprinted polymers

The development of selective sorbents for the separation of various molecules, preferentially biomolecules, is described in this work. Affinity ligands were immobilized on small silica particles and used in high-performance liquid affinity chromatography (HPLAC). With this technique, it is possible to perform fast, selective and efficient bioseparations. Methods were developed for the preparation

Product development problematics

The study of life in confined extreme environments to give guidance for issues and conditions for the design, development and production of objects on Earth. We use long term living in confined extreme environments as starting point for studies of product development concerning objects and living environments. By using the extreme environment as a backdrop for our studies we aim to achieve a labor

MHC and Transgenic Mice. A study into polymorphism and function of class I and class II molecules

Popular Abstract in Swedish Vi är under ständig attack från mikroorganismer som vill leva på oss och i oss. Vissa av dessa är vanligtvis nyttiga medan andra är sjukdomsframkallande. Kroppens försvar mot invaderande organismer består av många delar. Ytterst sitter huden som en mekanisk barriär, vi har slem och epitelceller i luftvägar och magtarmkanal samt skyddande ämnen i exempelvis tårvätska. I Transplantation antigens encoded in the major histocompatibility complex (MHC) bind peptides and present them to T cells. We showed that mouse T cells expressing transgenic human CD8 can recognise human MHC class I. Expression on mature T cells is sufficient for activation in a mixed lymphocyte culture but expression both on thymocytes and mature T cells is necessary for peptide specific MHC restr

On information rates for faster than Nyquist signaling

In this paper we consider the information rates of faster than Nyquist (FTN) signaling schemes. We consider binary, quaternary and octal schemes that use root raised cosine pulses. Lower and upper bounds to the information rates are given. The main result is that the lower bounds are often above the information rates for standard Nyquist signaling schemes. This implies that FTN must be superior to

Denitrification as an adaptive trait in soil and groundwater bacteria

The focus of the thesis is on selection and adaptation processes in bacteria with emphasis on denitrifying bacteria in groundwater. Other nitrogen transformation processes such as dissimilatory nitrate reduction to ammonium (nitrate ammonification) and nitrification of forest soil bacteria are briefly discussed. Intensive fertilisation of agricultural soils in southern Sweden have been performed