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Clinical trials frequently include multiple end points that mature at different times. The initial report, typically based on the primary end point, may be published when key planned co-primary or secondary analyses are not yet available. Clinical Trial Updates provide an opportunity to disseminate additional results from studies, published in JCO or elsewhere, for which the primary end point has

The Freedom Theatre is one of the most remarkable institutions in occupied Palestine, and indeed the world. Nestled in Jenin refugee camp in the West Bank, the theatre has faced attacks, threats, imprisonment of many functionaries, and the assassination of its co-founder. And yet the theatre has not only endured, it has grown, from a provisional hall with rented plastic chairs to one of Palestine'The Freedom Theatre is one of the most remarkable institutions in occupied Palestine, and indeed the world. Nestled in Jenin refugee camp in the West Bank, the theatre has faced attacks, threats, imprisonment of many functionaries, and the assassination of its co-founder. And yet the theatre has not only endured, it has grown, from a provisional hall with rented plastic chairs to one of Palestine'

Applying research into assessments of community theatre, epidemiology, and young people's shared and private stories using a wide range of methodologies, this book explores the potential efficacy of community theatre to prevent the spread of HIV/AIDS in Tanzania with reference to several other comparable sites in Africa.Applying research into assessments of community theatre, epidemiology, and young people's shared and private stories using a wide range of methodologies, this book explores the potential efficacy of community theatre to prevent the spread of HIV/AIDS in Tanzania with reference to several other comparable sites in Africa.

Essentially all plasma membrane proteins are glycosylated, and their activity is regulated by tuning their cell surface dynamics. This is achieved by glycan-binding proteins of the galectin family that either retain glycoproteins within lattices or drive their endocytic uptake via the clathrin-independent glycolipid-lectin (GL-Lect) mechanism. Here, we have used immunofluorescence-based assays to

International collaboration is an important indicator of research excellence and quality. Not only is international collaboration necessary to maintain or strengthen competitiveness on individual, organisational and aggregated national levels, but it is also necessary to find solutions to global challenges and increase understanding between different countries and cultures.

This study reviews the literature on TOUCH to establish an analytical framework for the study of TOUCH in communication through language. Two questions are at the heart of the study—an ontological and a methodological one: What counts as TOUCH, and how can we investigate the way we talk about TOUCH? Within the broad framework of cognitive semantics, we offer a general approach to TOUCH and identif

Russia, Eurasia, and Eastern Europe remain an important hub for migration, with significant implications for both the societies in the region and migrants themselves. Migration can affect illiberal practices by contributing to political polarization, the adoption of restrictive immigration policies, the spread of xenophobia and discrimination, and economic competition. Global Migration and Illiber

This chapter analyses the impact which Russia’s war in Ukraine, as the manifestation of illiberal politics in Russia, has had on migra­tion. We outline key developments in Russia’s security policy and the shift towards ideological and disruptive illiberalism rooted in Soviet and imperial traditions and examine the war’s impact on mobilities within and from Central Asia, specifically looking at wha

Lisbeth Nilsson Summary presentation Kids Loco I am most thankful to meeting with sensai Junichi Takashio in England 2012 and getting the opportunity to visit Biwako Gakuen in 2014, and returning to Japan in 2017 and 2018. Thanks to these meetings Driving to Learn and the Assessment of Learning Powered mobility use (ALP) became known in Japan. This presentation will show what develops if an infant

Energy-efficient building designs, notably through adding insulation, can reduce energy consumption and greenhouse gas emissions by over 40 %, but may also increase risk of condensation. Therefore, a comprehensive decision analysis approach is essential for selecting optimal building envelope assemblies while considering their hygrothermal, economic, and environmental implications. This study intr

This chapter aims to provide practical evidence-based guidance in the use of generative artificial intelligence (GenAI) for the design and management of authentic assessment tasks and provide a grounding for institutional policy conversations so that decisions can be influenced in a constructive learner-centric way. Drawing on the foundational principles of assessment and feedback, we critically e

BACKGROUND: Obesity, assessed by body mass index (BMI), is an established risk factor for 13 cancers. We aimed to identify further potential obesity-related cancers and to quantify their association with BMI relative to that of established obesity-related cancers.METHODS: Using Cox regression models on 4,142,349 individuals in Sweden (mean age 27.1 years at weight measurement), we calculated hazar

A search is presented for the pair production of higgsinos χ˜ in gauge-mediated supersymmetry models, where the lightest neutralinos χ˜1 0 decay into a light gravitino G˜ in association with either a Higgs h or a Z boson. The search is performed with the ATLAS detector at the Large Hadron Collider using 139 fb−1 of proton–proton collisions at a centre-of-mass energy of s=13TeV. It targets final st

The rise of business angel groups represents a shift in the early-stage financing landscape. This thesis examines the heterogeneity and dynamics of angel groups, focusing on two interconnected research questions: (1) How do financial capital, locus of decision-making, and formalization influence exit strategies within angel groups? and (2) How do angel groups leverage their collectiveresources to

Following dramatic changes in the international security environment, civil defence has reemerged as a central priority of governments, which requires collaboration among many stakeholders across sectors and levels of authority. Conditions for achieving such collaboration is a long-standing topic in different literatures, yet this is still a nascent topic in the study of civil defence and prepared

Researchers have pointed to challenges in the implementation of integratedpolicy, as policymaking is undertaken in highly vertical structures withdiverse policy goals, content and processes in different policy subsectors.This article studies cultural and creative industries (CCI) policymakingwith an integrative ambition. It contributes to knowledge of CCE support byunpacking the policymaking proce

The identification of susceptible dust sources (SDSs) based on the analysis of effective factors (i.e. dust drivers) is considered to be one of the primary and cost-effective solutions to deal with this phenomenon. Accordingly, this study aimed to identify SDSs and delineate their drivers using remote sensing data and machine learning (ML) algorithms in a hotspot area in the Lower Mesopotamian flo

A combination of searches for Higgs boson decays into a visible photon and a massless dark photon (H → γγd) is presented using 139 fb−1 of proton-proton collision data at a centre-of-mass energy of s = 13 TeV recorded by the ATLAS detector at the Large Hadron Collider. The observed (expected) 95% confidence level upper limit on the Standard Model Higgs boson decay branching ratio is determined to