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Periarticular bone in rheumatoid arthritis versus arthrosis. Histomorphometry in 103 hip biopsies
Histomorphologic differences of the periarticular bone in rheumatoid arthritis (RA) and osteoarthrosis (OA) may be of importance for long-term prosthetic fixation. We have evaluated bone specimens, obtained during total hip replacement from an acetabular and a femoral biopsy site, in 42 RA-hips and 61 OA-hips. In both groups the bone turnover was increased in the acetabulum compared to that in the
Plasma bikunin: half-life and tissue uptake
Bikunin is a chondroitin sulfate-containing plasma protein synthesized in the liver. In vitro, it has been shown to inhibit proteases and to have additional activities, but its biological function is still unclear. Here we have studied the dynamics of plasma bikunin in rats and mice. A half-life of 7 +/- 2 min was obtained from the time course of the decrease of the plasma level of bikunin followi
Infektioner hos reservdelsmänniskan - en epidemiologisk och klinisk översikt
Nordic research in ophthalmology.
Chloroplast membranes retard fat digestion and induce satiety: effect of biological membranes on pancreatic lipase/co-lipase
Human obesity is a global epidemic, which causes a rapidly increased frequency of diabetes and cardiovascular disease. One reason for obesity is the ready availability of refined food products with high caloric density, an evolutionarily new event, which makes over-consumption of food inevitable. Fat is a food product with high caloric density. The mechanism for regulation of fat intake has theref
The "Goldilocks Effect" in Cystic Fibrosis: identification of a lung phenotype in the cftr knockout and heterozygous mouse
Background: Cystic Fibrosis is a pleiotropic disease in humans with primary morbidity and mortality associated with a lung disease phenotype. However, knockout in the mouse of cftr, the gene whose mutant alleles are responsible for cystic fibrosis, has previously failed to produce a readily, quantifiable lung phenotype. Results: Using measurements of pulmonary mechanics, a definitive lung phenotyp
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The conflicts concerning the preservation or destruction of the deserted church of Mårup in Denmark is followed from the the moment in 1928, when the church became redundant, untill 2004. The protection of the church is in conflict with the protection of the eroding cliff, the church as a symbol in conflict with the church as a source material, and the local people in conflict with central authori
pH dependency of ligand binding to cellobiohydrolase 1 (Cel7A) - Affinity, selectivity and inhibition for designed propranolol analogues
The affinity and enantioselectivity have been determined for designed propranolol derivatives as ligands for Cel7A by capillary electrophoresis (CE) at pH 7.0. These results have been compared to measurements at pH 5.0. In agreement with previous studies, the affinity increased at the higher pH. However, the affinity was not as dependent of the ligand structure at pH 7.0 as at pH 5.0, and the sele
The cost of avian winter stores: intra-individual variation in basal metabolic rate of a wintering passerine, the greenfinch Carduelis chloris.
Fertility Response to Short-term Economic Stress: Deliberate Control or Reduced Fecundability?
Att skapa goda arbetsmiljöer - med hjälp av design och jämställdhet
Nonfatal stroke, cardiac disease, and diabetes mellitus in hypopituitary patients on hormone replacement including growth hormone
Context: The impact of long-term GH replacement on cerebrovascular and cardiovascular diseases and diabetes mellitus in hypopituitary patients is unknown. Objective: The incidence of nonfatal stroke and cardiac events, and prevalence of type 2 diabetes mellitus ( T2D) and cardioprotective medication were compared between cohorts of GH-deficient (GHD) patients and population controls. Design and Pa
Att gestalta historien
Prostate cancer risk and serologic evidence of human papilloma virus infection: a population-based case-control study.
Ariadne at HERA and at the LHC
I describe briefly the status of the ARIADNE program implementing the Dipole Cascade Model and comment both on its performance at HERA, and the uncertainties relating to the extrapolation to LHC energies.
Time trends in incidence and prevalence of human papillomavirus type 6, 11 and 16 infections in Finland.
Human papillomavirus (HPV) type 16 is the major cause of cervical carcinoma, the incidence of which is decreasing in western countries. In Finland the incidence is, however, increasing in women aged
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The multiple meaning of home as experienced by very old Swedish people
he aim of this study was to explore aspects of the meaning of home as experienced by very old single-living people in Sweden. A grounded theory approach was used, and interviews were conducted with 40 men and women aged 80-89. The findings indicate that home has a central place in the lives of very old people because it is where they live and spend so much time. The significance of the home is bas