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Completeness of case ascertainment in Swedish hospital‐based stroke registers

Some first‐ever stroke patients, such as those with high early case fatality and those with mild stroke, may go undetected with hospital‐based screening used in clinical stroke registers. This can result in selection bias due to not identifying specific groups of patients including some with high early case fatality and those living in healthcare facilities. New publication in Acta Neurologica Sca

https://www.lupop.lu.se/article/completeness-case-ascertainment-swedish-hospital-based-stroke-registers-0 - 2025-10-05

Functioning and disability from 10 to 16 years after traumatic brain injury

The very small changes over 6 years imply that persons with a TBI can reach and maintain a stable level of functioning many years post‐TBI. Women with a moderate‐to‐severe TBI seem to be more vulnerable and may experience a small decline in some aspects of their functioning related to anxiety, depression, irritability, pain and headache and fatigue. The relatively small sample requires further stu

https://www.lupop.lu.se/article/functioning-and-disability-10-16-years-after-traumatic-brain-injury - 2025-10-05

Understanding User Involvement in Research in Aging and Health

User involvement in research is advocated as an avenue for efficient societal developments. In this article, we identify potentials, problems, and challenges related to research on aging and health, and identify and illustrate research priorities using an evolving research program as an example. Involving user representatives in the development phase, the UserAge program engages researchers at fou

https://www.lupop.lu.se/article/understanding-user-involvement-research-aging-and-health - 2025-10-05

Reflections on modern methods: linkage error bias

Linked data are increasingly being used for epidemiological research, to enhance primary research, and in planning, monitoring and evaluating public policy and services. Linkage error (missed links between records that relate to the same person or false links between unrelated records) can manifest in many ways: as missing data, measurement error and misclassification, unrepresentative sampling, o

https://www.lupop.lu.se/article/reflections-modern-methods-linkage-error-bias - 2025-10-05

Twin Family Registries Worldwide: An Important Resource for Scientific Research

Much progress has been made in twin research since our last special issue on twin registries (Hur, Y.-M., & Craig, J. M. (2013). Twin Research and Human Genetics, 16, 1-12.). This special issue provides an update on the state of twin family registries around the world. This issue includes 61 papers on twin family registries from 25 countries, of which 3 describe consortia based on collaborations o

https://www.lupop.lu.se/article/twin-family-registries-worldwide-important-resource-scientific-research - 2025-10-05

Establishing a National Registry for Hand Surgery

Hand surgery leadership in the United States must identify and define what quality care means for its patients. To achieve this, the surgical team needs a standardized framework to track and improve quality. This is necessary not only in our value-based health care system but also in light of considerable provider variation in the management of common hand conditions and the ongoing need for evide

https://www.lupop.lu.se/article/establishing-national-registry-hand-surgery - 2025-10-05

Well-Being and Working Conditions of Teachers in Sweden

n Sweden, teachers are subject to high turnover, unfavorable working conditions, and high incidence of stress-related disorders. The aim of the present study was to (a) assess teachers’ perceptions of work-related health and working conditions, (b) examine the relationship among sev- eral key characteristics in teachers’ work environment, and (c) examine the importance for well-being of job satisf

https://www.lupop.lu.se/article/well-being-and-working-conditions-teachers-sweden - 2025-10-05

Understanding the complexity of socioeconomic disparities in type 2 diabetes risk: a study of 4.3 million people in Sweden

Investigating demographic and socioeconomic factors as intersecting rather than as separate dimensions may improve our understanding of the heterogeneous distribution of type 2 diabetes in the population. However, this complexity has scarcely been investigated and we still do not know the accuracy of these factors for predicting type 2 diabetes. Improved understanding of the demographic and socioe

https://www.lupop.lu.se/article/understanding-complexity-socioeconomic-disparities-type-2-diabetes-risk-study-43-million-people - 2025-10-05

Lifestyle and cancer incidence and mortality risk depending on family history of cancer in two prospective cohorts

The extent to which a favorable lifestyle may lower cancer risk in subjects with a family history of cancer is unknown. We conducted a prospective study in two Swedish cohorts, the Malmö Diet and Cancer Study (MDCS; n = 25,604) and the Malmö Preventive Project (MPP; n = 16,216). The association between a favorable lifestyle (based on nonsmoking, normal weight, absence of excessive drinking, regula

https://www.lupop.lu.se/article/lifestyle-and-cancer-incidence-and-mortality-risk-depending-family-history-cancer-two-prospective - 2025-10-05

Mental health and experience of being bullied in 12‐year‐old children with overweight and obesity

The aim was to study the association between weight, mental health and experience of being bullied in 12‐year‐old children. Additional aim was to investigate the impact of childhood psychosocial risk factors for overweight and obesity at age 12. New publication in Acta Paediatrica

https://www.lupop.lu.se/article/mental-health-and-experience-being-bullied-12-year-old-children-overweight-and-obesity - 2025-10-05

Discrepancies in the Registries of Diet vs Drug Trials

ClinicalTrials.gov was established in 2000 in response to the Food and Drug Administration Modernization Act of 1997, which called for registration of trials of investigational new drugs for serious diseases. Subsequently, the scope of ClinicalTrials.gov expanded to all interventional studies, including diet trials. Presently, prospective trial registration is required by the National Institutes o

https://www.lupop.lu.se/article/discrepancies-registries-diet-vs-drug-trials - 2025-10-05

Use of National Joint Registries to Evaluate a New Knee Arthroplasty Design

The introduction of new technology in joint replacement surgery requires close monitoring to identify early successes and failures. This monitoring can be effectively performed through the analysis of registry data and radiostereometric analysis studies. This study examined the revision rates of a contemporary knee system for total knee arthroplasty (TKA) using National Joint Replacement Registrie

https://www.lupop.lu.se/article/use-national-joint-registries-evaluate-new-knee-arthroplasty-design - 2025-10-05

In-hospital cardiac arrest and preceding National Early Warning Score (NEWS): A retrospective case-control study

We aimed to describe and evaluate the National Early Warning Score (NEWS) in the 24 hours preceding an in-hospital cardiac arrest among general somatic ward patients. The 24 hours preceding the in-hospital cardiac arrest were divided into four timespans and analysed by a medical record review of 127:254 matched case-control patients. The median NEWS ranged from 3 (2–6) to 6 (3–9) points for cases

https://www.lupop.lu.se/article/hospital-cardiac-arrest-and-preceding-national-early-warning-score-news-retrospective-case-control - 2025-10-05

Secular trends of sustained remission in rheumatoid arthritis, a nationwide study in Sweden

Of patients with symptom onset in the 1980s, 1990s and 2000s, 35.0, 43.0 and 45.6% reached SR, respectively (P < 0.001 for each increment), and the odds of SR were higher in every decade compared with the one before. The hazard ratio for reaching SR was 1.15 (95% CI 1.14, 1.15) for each year from 1994 to 2009 compared with the year before. Five years after symptom onset in 2009, 45.3% of patients

https://www.lupop.lu.se/article/secular-trends-sustained-remission-rheumatoid-arthritis-nationwide-study-sweden - 2025-10-05

Contributions of the UK biobank high impact papers in the era of precision medicine

To review the highest impact studies published from the UK Biobank and assess their contributions to “precision medicine.” We reviewed 140 of 689 studies published between 2008 and May 2019 from the UK Biobank deemed to be high impact by citations, alternative metric data, or publication in a high impact journal. We classified studies according to whether they were largely methods papers, largely

https://www.lupop.lu.se/article/contributions-uk-biobank-high-impact-papers-era-precision-medicine - 2025-10-05

Evaluation of a multimodal pain rehabilitation programme in primary care based on clinical register data: a feasibility study

There is insufficient knowledge on how to avert neck/back pain from turning chronic or to impair work ability. The Swedish Government implemented a national multimodal rehabilitation (MMR) programme in primary care intending to promote work ability, reduce sick leave and increase return to work. Since randomised control trial data for effect is lacking, it is important to evaluate existing observa

https://www.lupop.lu.se/article/evaluation-multimodal-pain-rehabilitation-programme-primary-care-based-clinical-register-data - 2025-10-05