Previous studies on lymphocytes have suggested that patients with head and neck squamous cell carcinoma (HNSCC) have an increased susceptibility for chromosomal damage induced by bleomycin, a known radiomimetic mutagen. However, it has so far not been possible to study whether this genetic instability is present also in the epithelial component of the upper aerodigestive tract mucosa, the tissue f

Patients with ulcerative colitis (UC) and Crohn´s colitis are at increased of developing colorectal cancer (CRC). However, recent studies suggest that the risk is now less than previously thought. Well established risk factors include extent and duration of disease, primary sclerosing cholangitis (PSC) and a family history of CRC. Recently inflammation (both microscopic and macroscopic) has been s

The ancient Egyptian site of Gebel el Silsila is known for its many pharaonic stelai, funerary shrines and the famous rock-cut chapel of Pharaoh Horemheb, but this article leaves the Pharaohs’ chronicles and explores instead a complex and mysterious marking system that is preserved as engravings in the site’s extensive quarries that run on both sides of the Nile. Here we will investigate Graeco-Ro

This article examines how Sharon Maguire’s romantic comedy Bridget Jones’s Diary (2001) both thematically and stylistically foregrounds the relationship between the protagonist’s voluntary and involuntary displays of emotions. It explores the use of cinematic techniques, underlining how the film speaks to our emotions, appealing both to high-level cognitive processes and low-level affective respon

This contribution provides interdisciplinary analysis of expressions of austerity-policies. It is argued that expressions of austerity-policies are meaningful if and only if intended addressees’ psychological states are adequately attuned and conceptual preconditions for implementation met. Furthermore, it is argued that if addressees are suitably psychologically attuned and preconditions met, uti

Background: Symptoms associated with primary headaches are linked to cranial vascular activity and to the central nervous system (CNS). Review: The central projections of sensory nerves from three cranial vessels are described in order to further understand pain mechanisms involved in primary headaches. Tracers that label small and large calibre primary afferent fibres revealed similar distributio

Despite an observable trend in reducing the number of layers in core and metropolitan area networks, still the optimal design of multi-layer networks (like IP over WDM) remains a important issue as a means to reduce CAPEX and OPEX. In multi-layer networks, usually a connection oriented transport network (like WDM) is used to deploy a layout for optimal transport of traffic. In today's networks, th

Abstract not available.

Idag utvecklas så mycket kunskap genom en strid ström av korta forskningsprojekt att det långvariga börjar höra till ovanligheterna. Just därför har vi stannat till inför det i dag 7-åriga samspelet mellan Tryckolera och Certec. Även det var ursprungligen ett tidsavgränsat projekt. Vad är det som har gett det en sådan bärkraft genom åren? Svaret överraskade oss själva: uthålligheten har uppkommit

BACKGROUND: Acute surgery in the management of malignant colonic obstruction is associated with high morbidity and mortality. The use of self-expanding metal stents (SEMS) is an alternative method of decompressing colonic obstruction. SEMS may allow time to optimize the patient and to perform preoperative staging, converting acute surgery into elective. SEMS is also proposed as palliative treatmen

The use of this material under current use conditions is supported by the existing information. This material was evaluated for genotoxicity, repeated dose toxicity, developmental toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity, skin sensitization potential, as well as, environmental safety. Reproductive toxicity was based on the Threshold of Toxicological Concern (TTC)

Raised plasma levels of the soluble urokinase plasminogen activator receptor (suPAR) have been associated with increased incidence of cardiovascular diseases. Whether suPAR is associated with venous thromboembolism (VTE) is largely unknown. The purpose of the present study was to investigate the relationship between suPAR and incidence of VTE in a cohort study. suPAR was measured in 5,203 subjects

The Cochrun-Grabel (C-G) method, an algorithm for finding the characteristic polynomial of a circuit containing reactances, has so far been restricted to circuits not employing mutual inductances. In this paper we present an intuitive, yet rigorous, proof of the Cochrun-Grabel method for a general RLC circuit, and we extend the method to allow the analysis of an RLC circuit containing mutual induc

Background: This study investigates the use of requests for clarification in conversations between teenagers with a cochlear implant (CI) and hearing peers. So far very few studies have focused on conversational abilities in children with CI. Aims: The aim was to explore co-construction of dialogue in a referential communication task and the participation of the teenagers with CI in comparison wit

BACKGROUND: Cerebral ischemia is usually characterized by a reduction in local blood flow and metabolism and by disruption of the blood-brain barrier in the infarct region. The formation of oedema and opening of the blood-brain barrier in stroke is associated with enhanced expression of metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinase-1 (TIMP-1). RESULTS: Here, we found an inf