Sökresultat

The European Medicines Agency (EMA) established the Patient Registry Initiative to explore ways of supporting the use of patient registries in generating high-quality data for regulatory decision making and to enable a systematic approach to their use. We review barriers and opportunities for using patient registries in medicines regulation. A key aspect is that early discussions between all parti

https://www.lupop.lu.se/article/barriers-and-opportunities-use-patient-registries-medicines-regulation - 2025-11-18

Soil-transmitted helminth infections have been found to be associated with child development. The objective was to investigate hemoglobin levels and malnutrition as mediators of the association between Ascaris infection and intelligence quotient (IQ) scores in children. New publication in Epidemiology.Read more here.

https://www.lupop.lu.se/article/bayesian-methods-exposure-misclassification-adjustment-mediation-analysis - 2025-11-18

Establishment of orthopaedic registers started in 1975 and many registers have been initiated since. The main purpose of registers is to collect information on patients, implants and procedures in order to monitor and improve the outcome of the specific procedure. New publicatoin in Efort.Read more here

https://www.lupop.lu.se/article/what-when-and-how-orthopaedic-registers-introduction-register-based-research-0 - 2025-11-18

Följande utlysningar från Vetenskapsrådet är nu öppna Gästforskarprogram inom klimat och miljö (Söks av organisation)Forskningstid för kliniker inom infektionsområdet: antibiotika och antibiotikaresistens  

https://www.lupop.lu.se/article/nya-utlysningar-fran-vr-1 - 2025-11-18

Följande utlysningar från Vetenskapsrådet är nu öppna Projektbidrag för planering av klinisk behandlingsforskningNätverksbidrag för samverkan inom klinisk forskning  

https://www.lupop.lu.se/article/nya-utlysningar-fran-vr-2 - 2025-11-18

The Chinese National Twin Registry (CNTR) currently includes data from 61 566 twin pair from 11 provinces or cities in China. Of these, 31 705, 15 060 and 13 531 pairs are monozygotic, same‐sex dizygotic and opposite‐sex dizygotic pairs, respectively, determined by opposite sex or intrapair similarity. Read more here.

https://www.lupop.lu.se/article/chinese-national-twin-registry-gold-mine-scientific-research - 2025-11-18

Application to epidemiological record data in a large-scale biobank (Tohoku Medical Megabank Organization, Japan) shows that a combination of kurPCA and RAMP effectively detects known errors or inconsistent patterns. Read more here.

https://www.lupop.lu.se/article/outlier-detection-questionnaire-data-biobanks - 2025-11-18

Socioeconomic status has a negative impact on swimming ability in Swedish children, a new BlueHealth study has found. Read more here.

https://www.lupop.lu.se/article/new-study-highlights-disparity-swimming-skills - 2025-11-18

A pan-European enterprise to provide a catalogue (https://bio.tools) of tools and databases that can be used in these workflows. bio.tools not only lists where to find resources, but also provides a wide variety of practical information. Read more here.

https://www.lupop.lu.se/article/biotools-registry-software-tools-and-data-resources-life-sciences - 2025-11-18

This Glossary, rooted primarily in the Canadian context but drawing on lessons from elsewhere, describes environmental public health regulatory practice in relation to health equity, including approaches that practitioners can use to contribute to addressing the social determinants of health. Read more here.

https://www.lupop.lu.se/article/glossary-health-equity-context-environmental-public-health-practice - 2025-11-18

Mediation analysis is a powerful tool for understanding mechanisms, but conclusions about direct and indirect effects will be invalid if there is unmeasured confounding of the mediator–outcome relationship. Read more here.

https://www.lupop.lu.se/article/approximate-sensitivity-analysis-unmeasured-mediator-outcome-confounding - 2025-11-18

Over the past decade, several large registries of patients with idiopathic pulmonary fibrosis (IPF) have been established. These registries are collecting a wealth of longitudinal data on thousands of patients with this rare disease. The data collected in these registries will be complementary to data collected in clinical trials because the patient populations studied in registries have a broader

https://www.lupop.lu.se/article/patient-registries-idiopathic-pulmonary-fibrosis - 2025-11-18

The Hamburg City Health Study (HCHS) is a large, prospective, long-term, population-based cohort study and a unique research platform and network to obtain substantial knowledge about several important risk and prognostic factors in major chronic diseases. A random sample of 45,000 participants between 45 and 74 years of age from the general population of Hamburg, Germany, are taking part in an ex

https://www.lupop.lu.se/article/rationale-and-design-hamburg-city-health-study - 2025-11-18

Surgical quality registries are important tools for both performing research and improving clinical practice. The Swedish National Knee Ligament Registry (SNKLR) has collected patient-reported and surgical data on more than 90% of the anterior cruciate ligament (ACL) reconstructions in Sweden. There has year-by-year been an increasing number of publications using data from SNKLR and the Scandinavi

https://www.lupop.lu.se/article/should-garbage-garbage-out-be-replaced-little-little-out-questionnaire-response-rates-need-be - 2025-11-18

Self-selection into prospective cohort studies and loss to follow-up can cause biased exposure-outcome association estimates. Previous investigations illustrated that such biases can be small in large prospective cohort studies. The structural approach to selection bias shows that general statements about bias are not possible for studies that investigate multiple exposures and outcomes, and that

https://www.lupop.lu.se/article/bias-self-selection-and-loss-follow-prospective-cohort-studies - 2025-11-18

Comorbidity in stroke is common, but comprehensive reports are sparse. We describe prevalence of comorbidity and the prognostic impact on mortality and functional outcome in a large national ischemic stroke cohort. New publication in SAGE Journals

https://www.lupop.lu.se/article/long-term-outcome-after-ischemic-stroke-relation-comorbidity-observational-study-swedish-stroke - 2025-11-18

Multiple asthma patient registries have been established globally to provide valuable information on current clinical management, including treatment patterns, adherence, and the long-term outcomes that are important to patients, providers, and other decision makers. New publication in Immunology

https://www.lupop.lu.se/article/step-right-direction-harmonizing-measures-use-asthma-patient-registries - 2025-11-18

An increasing number of patients with central nervous system (CNS) tumor could survive to reproductive age. However, it is largely unknown whether the history of CNS tumor might affect pregnancy outcome. We aimed to explore the risk of being born preterm among children of CNS tumor survivors. New publication in International Journal of Cancer

https://www.lupop.lu.se/article/risk-being-born-preterm-offspring-survivors-childhood-or-adolescent-central-nervous-system-tumor - 2025-11-18

To inform evidence-based practice in health care, guidelines and policies require accurate identification, collation, and integration of all available evidence in a comprehensive, meaningful, and time-efficient manner. Approaches to evidence synthesis such as carefully conducted systematic reviews and meta-analyses are essential tools to summarize specific topics. Unfortunately, not all systematic

https://www.lupop.lu.se/article/24-step-guide-how-design-conduct-and-successfully-publish-systematic-review-and-meta-analysis - 2025-11-18

Nu finns ett nytt nyhetsbrev från SND att läsa online, med bland annat ledare av Monica Lassi vid LU. Läs nyhetsbrevet här.

https://www.lupop.lu.se/article/natverksnytt-fran-snd - 2025-11-18