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Cisplatin, a platinum-based chemotherapeutic agent, is widely used as a front-line treatment for several malignancies. However, treatment outcomes vary widely due to intrinsic and acquired resistance. In this study, cisplatin-perturbed gene expression and pathway enrichment were used to define a gene signature, which was further utilized to develop a cisplatin sensitivity prediction model using th

Although the Red Army left the Danish island of Bornholm 76 years ago, the Russian invasion of Ukraine has brought the memories of those events to life again. This small island, stretched between Sweden and Poland and not so far away from Kaliningrad Oblast, is rediscovering the meaning of its recent past. Miłosz Jeromin Cordes met with Jakob Seerup, a PhD, researcher and curator at Bornholm’s Mus

Maxillary growth inhibition in patients with cleft lip and palate (CLP) is an undesired effect that may occur in the teens despite proper primary care. Dental malocclusion and distortion of facial appearance can be treated with external distraction osteogenesis (DO) of the maxilla. This entails a Le Fort I osteotomy, fastening a semi-circular distractor to the skull, distraction for three weeks, a

Enterococcus faecalis cells can reduce ferric ions and other electron acceptors by extracellular electron transfer (EET). To find mutants with enhanced or defective EET, strain OG1RF with random transposon insertions in the chromosome was screened for ferric reductase activity by colony zymogram staining using the chromogenic ferrous-chelating compound Ferrozine. The screen revealed npr, eetB, and

Purpose: Environmental factors contribute substantially to risk for drug use disorders (DUD). The current study applies multiple methods to empirically test whether military service is associated with subsequent DUD, as previous findings are inconsistent. Methods: Longitudinal Swedish national registry data on a cohort of male conscripts born 1972–1987 (maximum N = 485,900) were used to test the a

This text focuses on the presence of calcium and phosphorus in connection with copper-alloy residue on the inside of melting crucibles from south Sweden dated to the late Bronze Age (ca. 1100 - 500 BC). The increase of Ca and P on the crucibles is not seen in general or overall but instead observed as a relative increase only on the inside were the metal was melted. The authors of this article wis

When Gomułka came to power, cruises to the West, mainly on the Baltic Sea, were allowed on the "Mazowsze" tourist ship. It usually passed Bornholm and moored at a safe distance from the island, so that cruisers could see the hostile West, but they did not taste it. In August 1957, on the first day of the layover, two young men jumped off the ship and swam a few hundred meters to Snogebaek south of

Abstract: Optical flow provides an opportunity to elevate the resolution and sensitivity of deflection sensing in background-oriented schlieren (BOS). Despite extensive relevant literature within the field of computer vision, there is a lack of proper quantification of its abilities and limitations with regard to the state-of-the-art BOS experiments. Thus, this study performs an assessment of accu

A new class of palladium complexes bearing bidentate 2-hydroxypyridine based ligands have been prepared and fully characterized. The applications of these new complexes towards ketone alkylation reactions with alcohols through a metal-ligand cooperative borrowing-hydrogen (BH) process were demonstrated.

Soil stabilisation techniques often use cement or lime asstabilising agents. Lately there has been an increase inusing blended binders. Mixing cement with slag or cementwith ¯y ash has gained in popularity. The prime purposeof blending binders is to reduce the costs. Other aims areto use waste material or to produce a new binder withbetter properties. Blending binders does not automaticallyresult

The interaction of alkali ions with multilayer graphene is critical in many applications, for example in energy storage devices. This requires a detailed understanding of ion interactions with carbonaceous layers. The mechanism of ion intercalation into graphene can be different from that observed for hard graphite. In this paper, we present an investigation of the vertical alkali ion (Na, K, Cs)

Static program analysis plays a crucial role in ensuring the quality and security of software applications by detecting and fixing bugs, and potential security vulnerabilities in the code. The use of declarative paradigms in dataflow analysis as part of static program analysis has become increasingly popular in recent years. This is due to its enhanced expressivity and modularity, allowing for a h

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Corporate net-zero emission pledges have multiplied in recent years, with estimates suggesting that more than 1000 companies have made such commitments. While seemingly indicative of companies stepping up to address climate change, critics have argued that pledges may be mere greenwashing if they rely on excessive offsetting and legitimise business-as-usual. Considerable grey and academic literatu

This article explores transnational anti-gender networking promoting “the natural family.” We focus on the World Congress of Families (WCF) and investigate how it is organized transnationally. We draw on international relations theory on challenges to the liberal international order as well as on theories on transcalar activism. The empirical material includes observations from two conferences and

This article concerns legal representatives’ negotiations around the principle of children’s best interests and children’s right to participation according to the Convention on the Rights of the Child, in cases of families applying for asylum in Sweden. Using material from nine interviews with children’s advocates, we analyse their strategies for obtaining narratives from children without putting

In this article, we analyse initiatives by and on behalf of undocumented migrants through Hannah Arendt’s notions of action and fabrication. We take three initiatives from the city of Malmö, Sweden, as our empirical examples: a musical, a relay, and a tent-camp action. By showing how these initiatives involve not only action and speech but also a fabrication of things, including works of art, we e