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PATRIK MEDSTRAND Patrik Medstrand_LUCRIS Patrik Medstrand_PubMed

https://www.virology.lu.se/clinical-virology/publications - 2025-10-15

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https://www.virology.lu.se/clinical-virology/collaborators - 2025-10-15

Patrik Medstrand, Professor E-post: patrik [dot] medstrand [at] med [dot] lu [dot] se (patrik[dot]medstrand[at]med[dot]lu[dot]se) Professor vid Klinisk virologi, Malmö Telefon: +46 46 222 14 89 Mobil: +46 70 841 57 97 Rumsnummer: BMC B1354b Professor vid EpiHealth: Epidemiology for Health Chef vid Klinisk virologi, Malmö Forskargruppschef vid Klinisk virologi, Malmö

https://www.virology.lu.se/clinical-virology/contact - 2025-10-15

HIV-1 and HIV-2 host interactions - - Lund University Karlsson I, Tingstedt JL, Sahin GÖ, Hansen M, Szojka Z, Buggert M, Biague A, Da Silva Z, Månsson F, Esbjörnsson J, Norrgren H, Medstrand P, Fomsgaard A*, and Jansson M*; Sweden-Guinea-Bissau Cohort Research Group. Cross-Reactive Antibodies With the Capacity to Mediate HIV-1 Envelope Glycoprotein-Targeted ADCC Identified in HIV-2-Infected Indivi

https://www.virology.lu.se/hiv-host-interactions/marianne-jansson - 2025-10-15

Marianne Jansson Marianne Jansson_LUCRISMarianne Jansson_PubMed  

https://www.virology.lu.se/hiv-host-interactions/publications - 2025-10-15

https://www.protein-chemistry.lu.se/protein-chemistry-group - 2025-10-15

The Medical Protein Chemistry research group headed by prof. Anna Blom is located at the Wallenberg Laboratory within Skåne University Hospital in Malmö. The group is focused on the complement system in health and disease. Our ambition is to make high quality basic science based on clinically relevant questions and yielding novel diagnostic approaches and clinical interventions. Our research is su

https://www.protein-chemistry.lu.se/anna-blom-research-group-0 - 2025-10-15

The Medical Protein Chemistry research group headed by prof. Anna Blom is located at the Wallenberg Laboratory within Skåne University Hospital in Malmö.  The group is focused on the complement system in health and disease. The complement, crucial part of innate immune system is involved in many basic biological processes such as defence against infections but when activated in a wrong place or no

https://www.protein-chemistry.lu.se/protein-chemistry-research-group - 2025-10-15

Best publications from our group over past years. King B.C., Kulak K, Krus U., Rosberg R., Golec E., Wozniak K., Gomez M.F., Zhange E., O'Connell D., Renström E. and Blom A.M. (2019) Complement C3 proteinst against autophagy related beta-cell detah via ATG16L1 interaction and regulation of autophagy., Cell Metabolism, 29, 202-210.Kulak K., Kuska K., Colineau L., Mckay M., Maziarz K., Slaby J., Blo

https://www.protein-chemistry.lu.se/top-publications - 2025-10-15

List of selected publications from our research group exemplifying the projects we are conducting. Blom. A. M., Pertoft H. and Fries E. (1995) Inter-a-inhibitor is required for the formation of the hyaluronan-containing coat on fibroblasts and mesothelial cells. J. Biol. Chem., 270, 9698-9701. Blom A. M., Mörgelin M., Öyen M., Jarvet J. and Fries E. (1999) Structural characterization of inter-a-in

https://www.protein-chemistry.lu.se/top-publications/selected-publications-group - 2025-10-15

In blood, complement proteins are a major component and perhaps therefore most of these were identified already decades ago. However, only in recent years it has become apparent that complement not only plays a major role in innate defense against pathogens but also identifies foreign materials and removes waste (immune complexes and dying cells). The physiological relevance of complement is demon

https://www.protein-chemistry.lu.se/projects - 2025-10-15

We are studying an unexpected role of complement – in the physiology and metabolism of pancreatic beta-cells. Surprisingly, this is related to intracellular functions of complement and therefore changes the way we perceive this “blood” system and will likely inspire discovery of many other intracellular effects of complement. We study the role of intracellular complement factor C3 and membrane bou

https://www.protein-chemistry.lu.se/projects/insulin-and-immunity-when-complement-takes-control - 2025-10-15

As a first line of defense against pathogens and a mediator between innate and adaptive immunity, complement is a particular focus of evasion strategies developed by pathogens.  We showed that one common strategy is to bind complement inhibitor C4BP, which leads to decreased opsonisation of bacteria with C3b impairing phagocytosis and allowing bacterial survival. It appears that binding of C4BP is

https://www.protein-chemistry.lu.se/projects/bacterial-complement-evasion-strategies - 2025-10-15

  Misguided or excessive complement activation is involved in many common diseases such as rheumatoid arthritis, systemic lupus erythematosus, vasculitis and age-related macula degeneration. In collaboration with clinicians we are studying molecular mechanisms of complement involvement in these diseases. Joint inflammation in rheumatoid arthritis (RA), a common chronic inflammatory disease that ca

https://www.protein-chemistry.lu.se/projects/pathologic-complement-activation-diseases - 2025-10-15

Complement-dependent cytotoxicity is one of the mechanisms by which therapeutic monoclonal antibodies are toxic to cancer cells. Also, complement is currently undergoing re-appreciation of its role in the immune surveillance of tumors. The majority of human tumors are low immunogenic and complement may be involved in their recognition via direct “danger signal” elicited activation. This in turn at

https://www.protein-chemistry.lu.se/projects/complement-and-cancer - 2025-10-15

Complement has recently gained substantial worldwide attention, as it was discovered that several common diseases such as age-related macular degeneration (blindness in elderly) are related to deregulation of the balance between complement activation and inhibition. Full complement deficiencies lead to severe infectious and autoimmune diseases but are uncommon while it appears that we are just beg

https://www.protein-chemistry.lu.se/projects/inherited-deficiencies-complement-inhibitors - 2025-10-15

 You can reach us by mailor by calling 040-33 78 30 and 040-33 15 20Vaishnavi Dandavate, postdoctoral fellowE-mail: vaishnavi [dot] dandavate [at] med [dot] lu [dot] se (vaishnavi[dot]dandavate[at]med[dot]lu[dot]se)Daniel Chacón Arguedas, postdoctoral fellowE-mail: daniel [dot] chacon_arguedas [at] med [dot] lu [dot] seLucia Fernandez-Nevado, postdoctoral fellowE-mail: lucia [dot] fernandez_nevado

https://www.protein-chemistry.lu.se/members-our-research-group - 2025-10-15

Here you can find description of open positions and internships in our research group. MSc StudentsWe often can offer thesis projects for Masters students within the projects conducted in our group. Please, contact Anna Blom (Anna [dot] Blom [at] med [dot] lu [dot] se (Anna[dot]Blom[at]med[dot]lu[dot]se)) directly for more details.PhD StudentsWe are always interested in reviewing PhD students appl

https://www.protein-chemistry.lu.se/open-positions - 2025-10-15

Research funding supporting projects conducted in our research group: Swedish Research Council Cancerfonden Torsten Söderberg Foundation ALF Knut and Alice Wallenberg Foundation Novo nordisk fonden Erling-Persson Family Foundation Alfred Österlund Foundation  Grants for clinical research from Skåne University Hospital (including cancer) King Gustav Vth, 80-years Anniversary Foundation Diabetesfond

https://www.protein-chemistry.lu.se/research-funding - 2025-10-15

Medical Protein Chemistry Group. Who are we? Professor Anna Blom leads the Medical Protein Chemistry group Projects conducted in our research group Open positions Lund University Diabetes Centre Department of Translational Medicine

https://www.protein-chemistry.lu.se/protein-chemistry - 2025-10-15