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Obesity is a common cause of diabetes, heart disease and early death, but risk differs greatly from one person to the next. In work led by researchers at Lund University in Sweden as part of the Innovative Medicine Initiative project SOPHIA, a pioneering clinical risk prediction algorithm has been developed that splits obesity into 5 separate diagnostic profiles each with contrasting health conseq

https://www.medicine.lu.se/article/new-precision-medicine-approach-helps-detect-subgroups-people-obesity-high-risk-diabetes-and-heart - 2025-11-19

Diabetes researcher Joao Duarte specialices in studying what happens in the brain in diabetes. In his research, he is also investigating how diet changes can improve brain function in connection with diabetes. He will be awarded this year's Medeon stipend on the World Diabetes Day Skåne event in Malmö on November 14. "I hope that my research can contribute to an increased awareness of the importan

https://www.medicine.lu.se/article/praised-research-diabetes-and-dementia - 2025-11-19

In 2025, children within the TEDDY study will submit their final samples at research clinics in Sweden, Finland, Germany and the United States. The international study has provided a lot of new knowledge about type 1 diabetes and how the disease develops. Analysis of the samples will continue with the aim of preventing the disease. Sweden and Finland are the two top countries for incidence rates o

https://www.medicine.lu.se/article/new-knowledge-about-type-1-diabetes-large-scale-teddy-study-will-soon-be-completed - 2025-11-19

Malin Parmar, professor of cellular neuroscience, along with three researchers in Italy and Denmark, has been awarded the prestigious ERC Synergy Grant worth EUR 10 million. The four researchers aim to develop custom-made neurons from stem cells for cell therapies to treat Parkinson’s or Huntington’s disease. Congratulations!“Thank you, it feels really fun and exciting for many reasons! One reason

https://www.medicine.lu.se/article/erc-synergy-grant-awarded-development-custom-made-stem-cell-therapies - 2025-11-19

A research team at Lund University in Sweden has discovered a certain type of cells – foam cells – in patients with the aggressive brain tumour glioblastoma. It has been shown how these cells accelerate the cancer’s growth and that this can be successfully inhibited using a drug developed for arteriosclerosis. Glioblastoma affects around 500 Swedes every year and is the most common and most aggres

https://www.medicine.lu.se/article/foam-cells-brain-tumours - 2025-11-19

After 20 years of research on gene therapy and the rare blood disease, Diamond-Blackfan Anemia, DBA, researcher Johan Flygare had reached a point where he and his colleagues had done everything they could in the lab. Even though they had proof of concept their gene therapy would work, engaging companies had been difficult. Then, in 2021, he received an e-mail. LONGREAD. The message came from Ameri

https://www.medicine.lu.se/article/science-start-developing-gene-therapy-rare-blood-disorder - 2025-11-19

Bioelectronics research and development of implants made of electrically conductive materials for disease treatment is advancing rapidly. However, bioelectronic treatment is not without complications. Researchers at Lund University in Sweden have taken another step forward by developing a refined method to create detailed and tissue-friendly bioelectronics. In a study published in Advanced Science

https://www.medicine.lu.se/article/using-light-create-bioelectronics-inside-body - 2025-11-19

It has been a year ago since bacteria from war-wounded at hospitals in Ukraine were analysed. The study, which attracted a lot of attention, showed that some of the bacteria types had total resistance to antibiotics. Now, the same researchers have examined the infectiousness of the bacteria. "The bacterium 'Klebsiella pneumoniae', which is resistant to all antibiotics, is also particularly aggress

https://www.medicine.lu.se/article/pandrug-resistant-bacteria-war-ukraine-are-extremely-pathogenic - 2025-11-19

An international team of researchers, led by scientists at Lund University, has uncovered how magnesium enters mitochondria. Magnesium is a vital mineral that plays a key role in numerous biological processes in the body. Among other functions, it is crucial for the mitochondria—the power plants of our cells—to produce and utilize ATP, the body’s primary energy molecule. When mitochondrial functio

https://www.medicine.lu.se/article/auto-regulating-channels-supply-our-cells-magnesium - 2025-11-19

A team of international researchers led by Professor Johan Jakobsson at Lund University has secured a 52 million SEK grant from the Aligning Science Across Parkinson’s (ASAP) initiative, in partnership with the Michael J Fox Foundation to investigate how mobile genetic elements —commonly referred to as "jumping genes"—contribute to neuroinflammation and the progression of Parkinson’s disease. Jump

https://www.medicine.lu.se/article/52-million-sek-goes-uncovering-genetic-drivers-parkinsons-disease-0 - 2025-11-19

People with type 2 diabetes have a higher risk of developing cardiovascular disease and dying prematurely due to atherosclerosis. A research team at Lund University in Sweden has now identified molecular mechanisms that may explain the increased risk. Their discovery may lead to more accurate treatments for patients with atherosclerosis and type 2 diabetes in the future. People with type 2 diabete

https://www.medicine.lu.se/article/new-explanation-dangerous-atherosclerotic-plaques-type-2-diabetes - 2025-11-19

An observational study from Lund University in Sweden examining sugar consumption has attracted considerable international attention. The study shows that sweetened beverages have a greater negative impact on health than other sources of sugar. They significantly increased the risk of ischaemic stroke, heart failure, atrial fibrillation and abdominal aortic aneurysm. Of the 70,000 Swedes who took

https://www.medicine.lu.se/article/questions-and-answers-lund-university-sugar-study - 2025-11-19

Nicholas Leigh came from the United States to Sweden and Lund University four years ago. In his research, he focuses on salamanders and how they can recreate body parts such as legs, tails and even components of the heart. It was the ability of moose to grow new antlers after shedding that first sparked Nicholas Leigh’s interest in regenerative research. For practical reasons, the choice fell on s

https://www.medicine.lu.se/article/seeking-shutdown-button-cancer - 2025-11-19

In 2022, Sweden became the first country in the world to allow body checking in women's ice hockey. Major hockey nations are now following Lund University's research on the consequences of tougher plays on the ice. A first study shows that almost nine out of ten players in the Swedish women's hockey league are in favour of body checking – regardless of their own size. “We found that interesting. T

https://www.medicine.lu.se/article/swedish-female-ice-hockey-players-favour-body-checking - 2025-11-19

Elite ice hockey players with a history of concussion report heightened mental health symptoms, according to a new study from Lund University in Sweden. In addition, one in five female hockey players suffered symptoms of burnout, and both sexes reported an alcohol consumption at a risk-level. The researchers based their study on Sweden’s two highest hockey divisions for men – the SHL and Hockeyall

https://www.medicine.lu.se/article/professional-ice-hockey-depressive-symptoms-and-burnout-linked-more-concussions - 2025-11-19

In type 2 diabetes, the body's ability to release insulin is impaired, which leads to high blood glucose levels. Research led from Lund University shows how the levels of a particular protein are elevated in the pancreas of people with type 2 diabetes. By knocking out the gene for the protein IGFBP7, the researchers discovered that insulin secretion was improved. Reduced insulin secretion leads to

https://www.medicine.lu.se/article/protein-affects-ability-secrete-insulin-type-2-diabetes - 2025-11-19

This year's recipient of the Leif C. Groop Award for Outstanding Diabetes Research maps out mechanisms in the adipose tissue, which has increased the understanding of why some people with obesity develop type 2 diabetes. Ingrid Wernstedt Asterholm at University of Gothenburg is spurred to find new answers when observations in the lab do not agree with the general view. Justification for awarding"I

https://www.medicine.lu.se/article/ingrid-wernstedt-asterholm-receives-leif-c-groop-award-research-adipose-tissue - 2025-11-19

New research results now published from Lund University’s MASAI trial are even better than the initial findings from last year: AI-supported breast screening detected 29 per cent more cases of cancer compared with traditional screening. More invasive cancers were also clearly detected at an early stage using AI. Now the final part of the research study will focus on breast cancer missed by screeni

https://www.medicine.lu.se/article/ai-supported-breast-cancer-screening-new-results-suggest-even-higher-accuracy - 2025-11-19

In patients with symptoms such as irregular heartbeats, dizziness, or fainting, or in individuals that physicians suspect may have atrial fibrillation, many days of ECGs may be required for diagnosis – “long-term ECG recordings”. These recordings must then undergo a time-consuming and human resource-intensive review to identify heart rhythm abnormalities. In a large international study, researcher

https://www.medicine.lu.se/article/ai-better-humans-analysing-long-term-ecg-recordings - 2025-11-19

Cold weather, dry air, an overactive immune system or our modern lifestyle. The causes may vary, but an increasing number of people are suffering from atopic eczema. In particular, children from higher socioeconomic backgrounds are at higher risk of developing the condition. However, there is help available and it is important to apply treatment early says Laura von Kobyletzki, a researcher at Lun

https://www.medicine.lu.se/article/atopic-eczema-widespread-disease - 2025-11-19