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Martiné Wlosinska, medical doctor and PhD student, will be defending her thesis titled “Preventing Cardiovascular Disease. Complementary precision medicine” on the 26th of November. In this interview, Martiné tells us about the effect of aged garlic extract on progression of cardiovascular disease and the importance of treating patients on a personalized level. Can you tell us more about your PhD

https://www.stemcellcenter.lu.se/article/phd-defence-interview-martine-wlosinska - 2025-10-05

Giulia Beneventi has investigated the role of RNA modifications and post-transcriptional control in cancer and stem cells. In this interview, she tells us about her research and what is it like to be a PhD student in newly established group. Giulia defends her thesis on the 8th of December.   What have you been working with during your PhD studies? The main aim of my PhD project was to unravel pos

https://www.stemcellcenter.lu.se/article/phd-defence-interview-giulia-beneventi - 2025-10-05

The Distinguished Professor programme was created by the Swedish Research Council to allow the most prominent researchers to conduct long-term, ground-breaking research which has great potential for achieving scientific breakthroughs. The Distinguished Professor programme is awarded to at least 2 scientists every second year between 2019-2029 by the Swedish Research Council. It was created to allo

https://www.stemcellcenter.lu.se/article/malin-parmar-awarded-distinguished-professorship-swedish-research-council - 2025-10-05

The career program Wallenberg Academy Fellows is the largest private investment in young researchers in Sweden. It provides the most promising young researchers with long-term resources, giving them excellent opportunities to establish themselves and build up their research groups. Wallenberg Academy Fellows is designed for young researchers and was launched by the Knut and Alice Wallenberg Founda

https://www.stemcellcenter.lu.se/article/daniella-rylander-ottosson-has-been-admitted-wallenberg-academy-fellow - 2025-10-05

Mikael has been investigating the influence of cellular heterogeneity in ontogeny, ageing and leukemia. In this interview, he tells us about his time as a PhD student in the group of Stem Cells and Leukemia at Lund Stem Cell Center. He defends his thesis on the 16th of December. What have you been working with during your PhD studies? My PhD project was aimed at resolving cellular heterogeneity wi

https://www.stemcellcenter.lu.se/article/phd-defence-interview-mikael-sommarin-0 - 2025-10-05

In their latest study, published in Nature Communications, the Parmar Lab has established midbrain organoids using silk microfibers as scaffolds, offering a refined in vitro model of human midbrain development. They have studied their silk midbrain organoids using single cell sequencing, proteomics and functional assessment in order to shed light on the developmental trajectory, maturation and sub

https://www.stemcellcenter.lu.se/article/human-midbrain-organoids-grown-silk-recapitulate-midbrain-development-and-support-functionally - 2025-10-05

In a recent study from the SCC group of Niels-Bjarne Woods and collaborators, they have investigated the metabolic changes accompanying the emergence of blood during embryonic development. They discovered a previously unknown metabolic switch during endothelial to hematopoietic transition (EHT), the process by which the first blood cells are formed. This switch showed to be crucial in the determin

https://www.stemcellcenter.lu.se/article/metabolic-switch-during-embryonic-hematopoiesis-major-regulator-lineage-commitment - 2025-10-05

Ludwig Schmiderer has studied how to overcome delivery challenges in stem cell biology with nanotechnology. In this interview, he tells us about his research and generative art. What have you been working with during your PhD studies? At the beginning of my PhD, I was trying to reengineer the CRISPR/Cas9 system to make it work in mitochondria instead of nucleus. The project started off quite well

https://www.stemcellcenter.lu.se/article/phd-defence-interview-ludwig-schmiderer - 2025-10-05

Stem cell transplantation is a cornerstone in the treatment of blood malignancies. In order to succeed, stem cells need to be harvested from a donor. This requires that hematopoietic stem and progenitor cells (HSPC) are mobilized from the donor’s bone marrow into the blood. In a new study, the Nilsson lab discovered DNA sequence variants that regulate HSPC levels in human blood, exposing potential

https://www.stemcellcenter.lu.se/article/large-scale-genome-wide-association-study-reveals-new-potential-drug-target-blood-stem-cell - 2025-10-05

The Pereira research group has previously shown that it is possible to reprogram human skin cells into dendritic cells that strengthen the immune system. However, the efficiency of these reprogrammed cells has been shown to be very low. New studies now indicate that there are ways to increase the efficiency of these reprogrammed cells by over 75%. These findings provide mechanistic insights into h

https://www.stemcellcenter.lu.se/article/new-findings-indicate-ways-increase-efficiency-reprogrammed-immune-cells - 2025-10-05

Anna Fossum, Project Manager at the StemTherapy FACS Core Facility research infrastructure, has been sorting cells with a variety of types of FACS machines for the past 23 years. But she hasn’t gotten tired yet of the job – quite the opposite. And now she has a new and more powerful member of the “FACS family” to look after. “I really love my job! It’s stimulating to meet so many people and hear a

https://www.stemcellcenter.lu.se/article/new-addition-lund-stem-cell-center-facs-facility - 2025-10-05

Researchers from Lund University, building on previous studies, have been working to understand why stem cells are transforming into cancer. Previously they revealed that small RNA molecules, long considered “junk” or degradation byproducts of RNA-sequencing, are emerging as key regulators of important cellular processes, like protein synthesis. Their latest discovery is published in Nature Cell B

https://www.stemcellcenter.lu.se/article/what-makes-stem-cells-transform-cancer-answer-may-lie-our-rna - 2025-10-05

Svetlana Soboleva is set to defend her Ph.D. thesis on 13 April, 2022. For the past few years her world has revolved around red blood cells, as she has worked to establish methods that allow for the generation of enucleated cells, using immortalized erythroid cell lines, to develop erythrocytes. In short, she’s been working to find ways to produce red blood cells in a lab. In this interview she te

https://www.stemcellcenter.lu.se/article/blood-lab-phd-defence-interview-svetlana-soboleva - 2025-10-05

This year Lund Stem Cell Center and MultiPark, two strategic research areas based at Lund University, are happy to launch a new joint technical platform in an effort to ensure easy access to high quality core electrophysiology techniques and expert knowledge for investigating cells and tissues that exhibit electrical properties. In 2009, the Swedish government decided to invest in strategic resear

https://www.stemcellcenter.lu.se/article/lund-scc-and-multipark-join-forces-ensure-researchers-have-high-quality-electrophysiology-facilities - 2025-10-05

The Marie Skłodowska-Curie Actions (MSCA) fund excellent research and innovation. This March, the MSCA awarded €242m to the 2021 Postdoctoral Fellowships applicants – among them, a researcher from Lund University, Camila Vazquez Echegaray, aiming to uncover regulators of plasticity in cell fate decision. The MSCA are the EU’s flagship funding programme for doctoral education and postdoctoral train

https://www.stemcellcenter.lu.se/article/msca-postdoctoral-fellowship-awarded-camila-vazquez-echegaray - 2025-10-05

Cancerfonden continues to fund the foremost cancer research in Sweden – investing in cancer research that makes a difference. Last month, Cancerfonden distributed SEK 37 million to eight researchers at Lund University whose work will contribute to defeating cancer. Included in this group of talented researchers, is postdoctoral researcher, Dr. Sowndarya Muthukumar, from the Lund Stem Cell Center.

https://www.stemcellcenter.lu.se/article/cancerfonden-awards-sowndarya-muthukumar-postdoctoral-fellowship - 2025-10-05

Cancer is a genetic disease, caused by a change in the genes which make up our DNA. Normally one change or mutation is not enough to trigger the development of cancer, instead cancer is typically comprised of a combination of genetic mutations. Researchers at Lund University have now revealed a novel somatic gene mutation is involved in the formation and progression of acute myeloid leukemia. The

https://www.stemcellcenter.lu.se/article/new-findings-reveal-what-may-be-triggering-disease-progression-acute-myeloid-leukemia - 2025-10-05

Researchers from Lund University, led by Dr. Laurent Roybon, are working to further define underlying mechanisms involved in neurodegenerative diseases, such as Parkinson’s Disease and Multiple System Atrophy. Their latest discovery, published in PNAS, could be used to devise novel therapeutic approaches to treat neurodegenerative diseases such as these, as well as other synucleiopathies in the fu

https://www.stemcellcenter.lu.se/article/new-findings-may-lead-way-future-therapeutic-approaches-parkinsons-disease-and-similar-diseases - 2025-10-05

Lund Stem Cell Center provides researchers with access to core facilities equipped with the latest technologies, specialist expertise and instruction on the use of the different equipment. Over time these facilities have evolved to form the well-developed technological infrastructure which exists today. Earlier this year, the Center, in partnership with MultiPark, took the next step in the evoluti

https://www.stemcellcenter.lu.se/article/new-cell-and-gene-therapy-core-facility-opening-its-doors-scientific-business - 2025-10-05

We are happy to announce that Sandeep Gopal, a researcher within the Department of Experimental Medical Sciences at Lund University, has now joined Lund Stem Cell Center. In his new role as Principal Investigator and leader of the research group on Extracellular Signaling and Cell Fate, he aims to better understand how extracellular molecules control cell fate and cell behavior. Previously based i

https://www.stemcellcenter.lu.se/article/lund-stem-cell-center-welcomes-new-member-sandeep-gopal - 2025-10-05