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BACKGROUND: Seizure duration during electroconvulsive therapy (ECT) correlates with treatment efficacy and may be influenced by depth of anaesthesia. The Patient State Index (PSi), derived from processed EEG, offers a potential method to monitor depth of anaesthesia during ECT. This study examined the correlation between pre-ictal PSi and EEG-seizure duration.METHODS: In this prospective observati

Background/Objectives: Older patients are more susceptible to the process of understanding and retrieving information. To provide adequate preoperative information, reduce their vulnerability and anxiety, and thereby facilitate pre-, intra-, and postoperative care, the adoption of new information technologies is essential. This study aimed to explore elderly patients' experiences and perceptions o

Cross-system fluxes of aquatic insects rich in omega-3 long-chain polyunsaturated fatty acids (ω-3 LC-PUFAs), specifically eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), may subsidise insectivorous vertebrates that are suffering due to terrestrial insect declines. The benefits of high ω-3 LC-PUFA diets, such as improved growth and immunocompetence, have previously been demonstrated fo

We present a new suite of edge ('Engineering Dwarfs at Galaxy formation's Edge') cosmological zoom simulations. The suite includes 15 radiation-hydrodynamical dwarf galaxies covering the ultrafaint to the dwarf irregular regime () to enable comparisons with observed scaling relations. Each object in the suite is evolved at high resolution () and includes stellar radiation, winds, and supernova fee

Atmospheric measurements of the short-lived radioactive noble gas radon-222 (222Rn) have many applications. Its concentrations are driven by atmospheric mixing as well as seasonal variations, which follow the seasonality of 222Rn exhalation from continental soils, with lower values during the wet winter and spring months compared to more dry summer conditions. Hence, it can be used as a tracer to

This paper reviews the recent advancements in inverter topologies and control techniques for grid-connected photovoltaic systems. As photovoltaic penetration continues to increase, modern power systems need high performance inverters which can maintain reliability, power quality and compliance with evolving grid codes. Although these inverters are advancing over the years, there is no existing rev

Here, we use carbon dioxide (CO2), methane (CH4), carbon monoxide (CO), nitrous oxide (N2O) and radon (222Rn) data from the Saclay ICOS tall tower in France to estimate CO2, CH4 and CO fluxes within the station footprint from January 2017 to October 2024 and N2O fluxes from February 2019 to October 2024 using the Radon Tracer Method (RTM). We first performed a sensitivity study of this method appl

Background: Wrist osteoarthritis (OA) is mainly posttraumatic, affects younger individuals than other types of OA, and can lead to significant disability. The first-line treatment is patient education and exercise, but surgery may be considered if symptoms persist. A mini-invasive surgical approach for wrist OA is partial wrist denervation, which,in theory, alleviates pain by resecting sensory ner

In pancreatic ductal adenocarcinoma (PDAC), the dense desmoplastic stroma and insufficient infiltrating T cells represent a significant barrier to effective immunotherapy. In this phase I, dose-escalation study, previously registered at the Dutch Trial Register and later on at ClinicalTrial (NCT05650918), we administer an autologous dendritic cell (DC) vaccine (MesoPher) with an agonistic CD40-spe

Natural history collections hold immense global significance – not only as historical archives but also as precious resources for novel scientific discoveries. These collections, housed in museums and institutions worldwide, are (or should be) accessible and open for study. In this paper, we provide a brief history of the fossil collections at Lund University, Sweden, tracing their origins, key hi

For the development of a joint European capacity for monitoring CO2 emissions, we created the framework “CO2 Monitoring Challenges City Mapbooks v1.0” (CMC-CITYMAP). It includes a Jupyter notebook tool (Storm et al., 2025a, https://doi.org/10.18160/P8SV-B99F) which we use to characterise and cluster cities based on aspects relevant for different CO2 monitoring challenges. These include:a. determin

We explore the decay of free neutrons into exotic long-lived particles, whose decays could be detected in the next-generation free neutron experiments. We show that such a possibility is viable as long as the exotic particle is highly mass-degenerate with the neutron, avoiding exclusion by large-volume detectors. We estimate the number of observable events and identify the most promising final sta

BACKGROUND: Monitoring of vital signs is essential in anaesthesia care and plays a key role in preventing adverse events. Technological innovation is recognised as an important factor in enhancing patient safety. Smart glasses represent a novel tool that may support anaesthesia professionals in monitoring vital signs; however, their practical use and user experiences in anaesthesia care remain ins

This study aimed to test and validate a dual-time-window (DTW) protocol for 6-(fluoro-18F)-3-(1H-pyrrolo[2,3-c]pyridin-1-yl)isoquinolin-5-amine ([18F]MK6240) dynamic PET imaging in experimental datasets acquired in human subjects. Methods: DTW protocols were tested and validated in datasets previously collected in 25 participants: 13 were cognitively normal, 10 had mild cognitive impairment, and 2

OBJECTIVES: Opioid-free anesthesia (OFA) is a promising alternative to traditional opioid-based anesthesia. Research indicates that OFA reduces postoperative opioid consumption and related adverse effects while maintaining effective pain control and patient safety. Despite these benefits, clinical adoption of OFA remains limited, possible due to gaps in evidence. To bridge this knowledge gap, a we

This thesis explores the spatial distribution of trees in the LPJ-GUESS dynamic global vegetation model and proposes some modification to improve ecological realism. In the standard version of LPJ-GUESS, the model simplifies forest dynamics by averaging individuals into cohorts and disregarding competition, canopy interactions or resource allocation completely. To improve this, a newer version was

We measured πΣ invariant mass spectra below and above the K̄N mass threshold in the K-d → NπΣ reaction in order to study the K̄N interaction and the Λ(1405) resonance. This reaction can be described by the two-step process: (i) K-N1 → K̄N followed by (ii) K̄N2 → πΣ, where N1 and N2 are nucleons bound in the deuteron. We deduced the S -wave scattering amplitude of K̄N → K̄N as well as K̄N → πΣ in I

Objectives: Many Japanese adults experience poor sleep quality. Prolonged sedentary behavior negatively affects health, including sleep-associated problems. We investigated the association between sedentary behavior and sleep quality among urban white-collar workers in Japan with metabolic syndrome or at risk of metabolic syndrome, a population thought to have particularly prolonged sedentary time

This paper sets out to discuss the relevance of the concept of the ”social help state” (socialhjälpstaten) within the framework of Swedish historiography by focusing on the organization of poor relief in Gothenburg between 1890 and 1920. Coined by Norwegian historian Anne Lise Seip in 1984, the term socialhjälpstaten has been used extensively in the study of early welfare institutions and provisio

Syftet med detta arbete är att undersöka om rullande bärighetsmätningar RWD är ett alternativ till fallviktsmätningar FWD i arbetet kring vägbärighet i vägprojekt. Bärighet beskrivs av Trafikverket som ” Den högsta last, enstaka eller ackumulerad, som kan accepteras med hänsyn till uppkomst av sprickor eller deformationer”. Det vill säga hur tunga fordon en väg eller en bro kan belastas med sThe purpose of this project is to investigate if RWD is an alternative to FWD in analysing road bearing capacity in road projects. According to the Swedish Transport Administration (Trafikverket), the definition of bearing capacity is described as “the maximum load whether single or cumulative, that can be accepted without causing cracking or deformation”. In other words, it refers to how muc