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Acute Postural Effects of Spinal Cord Injury : Dual Neural Opioid and Endocrine Non-Opioid Mechanism

Lateral spinal cord injury including lateral hemisection (LHS) leads to asymmetric postural and motor deficits. After traumatic brain injury, asymmetric postural deficits are partly developed through activation of opioid receptors. We here characterized the effects of LHS on hindlimb postural asymmetry (HL-PA), a proxy for neurological impairments, and assessed the involvement of opioid system. In

Evaluation of a Sensitive Visual Read Algorithm for Assessing 3R/4R Tau PET Images

Developing and validating sensitive visual read algorithms for assessing Alzheimer disease-related tau in tau PET imaging is imperative, considering the implementation of the methodology in clinical practice and trials. Our aim was to compare 2 visual read algorithms for tau PET images to semiquantitative measurements and plasma phospho-tau 217 (p-tau217) status. Methods: In total, 1,654 participa

Well-Controlled Mucosal Exudation of Undiluted Plasma Proteins Serves Innate and Adaptive Immunity

Distinct from the pulmonary circulation, the human respiratory mucosa is supplied by highly responsive, superficial, systemic microcirculations. In the early symptomatic phase of mucosal infections, circulating peptides-proteins of all sizes are released just beneath the epithelium and will soon appear on the mucosal surface. The traditional view is that mucosal injury must be involved in this pla

The effect of pupil size on data quality in head-mounted eye trackers

Changes in pupil size can lead to apparent gaze shifts in data recorded with video-based eye trackers in the absence of physical eye rotation. This is known as the pupil-size artifact (PSA). While the PSA is widely reported in desktop eye trackers, it is unknown whether and to what extent it occurs in head-mounted eye trackers. In this paper, we examined the effects of pupil size variations on eye

Neurophysiological evidence of rapid holistic tone-based lexical access

Word accents are restricted by a word’s morphological structure but also distinguish lexical meanings in minimal pairs. We investigated how early tonal information carried by morphophonemic word accents influences rapid lexical access in native speakers. We also asked whether tone-bearing words are decomposed into morphemes and word accents, or retrieved holistically via full-form neural represent

A high-voltage symmetric sodium ion battery using sodium vanadium pyrophosphate with superior power density and long lifespan

Sodium ion batteries have been considered as promising alternatives to lithium ion batteries for large-scale renewable energy and smart grids applications due to their low cost and rich resources. However, critical drawbacks such as low energy density and poor stability are hindering their development and application. In this work, a stable symmetric sodium ion cell using sodium vanadium pyrophosp

Investigation of Polymer/Ceramic Composite Solid Electrolyte System : The Case of PEO/LGPS Composite Electrolytes

The incorporation of inorganic lithium superionic conductors in polymer/ceramic composite electrolytes has been frequently proposed since this approach is expected to take advantage of the high ionic conductivities of the lithium superionic conductors and the elasticity of the polymer constituents of the composites. Nevertheless, the properties and mechanisms of polymer/ceramic composite electroly

TiO2@LiTi2(PO4)3 enabling fast and stable lithium storage for high voltage aqueous lithium-ion batteries

Anatase TiO2 is recognized as a promising negative electrode material when employing “water-in-salt” electrolytes in high voltage aqueous lithium-ion batteries. However, the catalytic property of water splitting aggravates the hydrogen evolution reaction, which hinders the formation of a stable solid electrolyte interphase (SEI) on the electrode surface and therefore results in poor cycling perfor

Tailoring of Gradient Particles of Li-Rich Layered Cathodes with Mitigated Voltage Decay for Lithium-Ion Batteries

Voltage decay during cycling is still a major issue for Li-rich cathodes in lithium ion batteries. Recently, the increase of Ni content has been recognized as an effective way to mitigate this problem, although it leads to lower-capacity materials. To find a balance between voltage decay and high capacity, particles of Li-rich materials with concentration gradients of transition metals have been p

Catching common vulnerabilities with code language models

Code Language Model (code-LM)-based vulnerability detection for C/C++ faces a substantial challenge. Previous research has shown that even though it is better than any prior machine learning approach, it still struggles to generalize well, as shown by the low F1 score. Prior works treated the problem as a binary classification: either vulnerable or non-vulnerable. Looking deeper at the various vul

Brain Organoid Transplantation : A Comprehensive Guide to the Latest Advances and Practical Applications—A Systematic Review

Brain organoid technology has seen significant development in recent years. This self-organized, three-dimensional, organ-oriented brain tissue model can recapitulate the process of neurogenesis and consists of diverse cell types and cellular architecture. Transplanting brain organoids in vivo could be a potential tool from bench to clinical research and has been studied for many purposes. To inve

The tidal deformation and atmosphere of WASP-12 b from its phase curve

Context. Ultra-hot Jupiters present a unique opportunity to understand the physics and chemistry of planets, their atmospheres, and interiors at extreme conditions. WASP-12 b stands out as an archetype of this class of exoplanets, with a close-in orbit around its star that results in intense stellar irradiation and tidal effects. Aims. The goals are to measure the planet's tidal deformation, atmos

Central Zika virus infection causes hypothalamic inflammation and persistent insulin resistance in adult mice

Zika virus (ZIKV) is a neurotropic flavivirus capable of infecting the adult brain, however its impact on hypothalamic function and metabolic regulation remains unclear. Here, we show that ZIKV invades the hypothalamus of immunocompetent adult mice, where it replicates and persists, leading to sustained insulin resistance. Following infection, ZIKV RNA and negative strand were detected in the hypo

Discovery of two warm mini-Neptunes with contrasting densities orbiting the young K3V star TOI-815

We present the discovery and characterization of two warm mini-Neptunes transiting the K3V star TOI-815 in a K–M binary system. Analysis of its spectra and rotation period reveal the star to be young, with an age of 200+−400200 Myr. TOI-815b has a 11.2-day period and a radius of 2.94 ± 0.05 R+ with transits observed by TESS, CHEOPS, ASTEP, and LCOGT. The outer planet, TOI-815c, has a radius of 2.6

Registerkvalitet och dess inverkan vid värdering av jordbruksmark

Syftet med detta examensarbete var att klargöra vilka statistikkällor innehållande arealuppgifter för jordbruksmark som finns åtkomliga samt att undersöka skillnaderna mellan de olika källorna. Intentionen var även att komma fram till förslag kring hur inhämtningen av taxeringsuppgifter vid fastighetstaxeringen kan förenklas respektive underlättas för fastighetsägare samt hur andra statistikkällorIn Sweden, the National Tax Board produces tax assessment values for all properties. This value is based on information obtained by the property owner during the property tax assessment and on the National Tax Board's developed guideline values. It is the value factors area, condition and drainage that affect the value. This thesis examines how the area data for agricultural land in different

Psychometric properties of the Dysexecutive Questionnaire (DEX) in individuals with a previous cardiac event

This psychometric study aimed to evaluate the psychometric properties of the Dysexecutive Questionnaire (DEX) following a cardiac event, and to examine the relationship between self- and informant-ratings. Approximately 7 months post-cardiac event, 196 participants and their informants (N = 179) completed the DEX. Reliability was assessed by confirmatory factor analysis and internal consistency esThis psychometric study aimed to evaluate the psychometric properties of the Dysexecutive Questionnaire (DEX) following a cardiac event, and to examine the relationship between self- and informant-ratings. Approximately 7 months post-cardiac event, 196 participants and their informants (N = 179) completed the DEX. Reliability was assessed by confirmatory factor analysis and internal consistency es

Compositional analysis of c13th century AD Mapungubwe ceramics in South Africa : regional, local and household connections

The 13th century AD in southern Africa is a period associated with the emergence of class-based society and the establishment of Mapungubwe as the capital of a regional state. This study reports on ceramics excavated from four households at Bosbokpoort, a small Mapungubwe settlement situated approximately 95 km from Mapungubwe. By combining traditional stylistic analysis with chemical (pXRF) and m

What is New in Contact Allergy To Cosmetics for Physicians, Cosmetologists, and Cosmetic Users?

Purpose of Review: This paper aims to evaluate the burden of contact allergy caused by cosmetic products, identifying the key allergens involved and examining recent regulatory and diagnostic developments. The review addresses which substances commonly induce allergic contact dermatitis and how current trends and emerging allergens impact clinical practice. Recent Findings: Fragrances remain the m

Magnetohydrodynamic simulation assessment of a potential near-ultraviolet early ingress in WASP-189b

Context. Ultra-hot Jupiters (UHJs) in close orbits around early-type stars provide natural laboratories for studying atmospheric escape and star-planet interactions under extreme irradiation and wind conditions. The near-ultraviolet (NUV) regime is particularly sensitive to extended upper atmospheric and magnetospheric structures. Aims. We investigate whether star-planet interactions in the WASP-1

Longitudinal tau aggregation, atrophy, and cognitive decline in Alzheimer's disease

INTRODUCTION: The independent contributions of baseline and longitudinal tau positron emission tomography (PET) and magnetic resonance imaging (MRI) to cognitive decline remain unclear. METHODS: We included n = 761 amyloid-positive individuals from the Swedish BioFINDER-2 study with [18F]RO948-tau-PET, 3-Tesla structural-MRI, and cognition (n = 322 with longitudinal imaging data). Linear-mixed-mod