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Green infrastructure (GI) is increasingly used in policymaking to promote biodiversity and enhance ecosystem services through the protection, creation, restoration and connection of natural and man-made green areas. The EU Commission adopted in 2013, the concept as a strategy. When member states apply the policy, it is translated into specific bureaucratic and political systems, creating different

Background: Sexual dysfunction is common following a cancer diagnosis in young adulthood (18–39 years) and problems related to sex life are ranked among the core concerns in this age group. Yet, few studies have investigated to what extent adults younger than 40, receive information from healthcare providers about the potential impact of cancer and its treatment on their sex life. Methods: A popul

The rapid expansion of industrial agriculture in rural Bogotá has led to a reduction in the diversity of plants cultivated by peasant families. This generates transformations in livelihoods and biocultural relations, affecting local environmental knowledge and practices for the use and management of agrobiodiversity. Although several studies have documented the presence of agrobiodiversity niches,

Objective: To report the risk of venous thromboembolism (VTE) after partial nephrectomy in Denmark. Materials and methods: A nationwide population-based registry was used to conduct a retrospective cohort study. All partial nephrectomies from January 2010 to August 2018 were assessed for postoperative VTE events. Univariable and multivariable analyses were used to evaluate the odds of postoperativ

Biogenic volatile organic compound (BVOC) emissions from trees subjected to biotic stress are higher compared to healthy trees, and they may also have a different compound composition. This in turn affects atmospheric chemistry and can lead to either positive or negative feedback to the climate. Climate change favors the abundance of the European spruce bark beetle (Ips typographus) which attacks

Evaluation is ubiquitous in current (academic) science, to the extent that it is relevant to talk about an evaluation regime. How did it become this way? And what does it mean for scientists, groups, organizations, and fields? Picking up on the inspiring debate in a previous issue of this journal, four articles in this special section go deeper in studying the causes and consequences of the curren

Purpose: We developed a method of standardizing the heart-to-mediastinal ratio in 123I-labeled meta-iodobenzylguanidine (MIBG) images using a conversion coefficient derived from a dedicated phantom. This study aimed to create a machine-learning (ML) model to estimate conversion coefficients without using a phantom. Methods: 210 Monte Carlo (MC) simulations of 123I-MIBG images to obtain conversion

Coastal eutrophication due to excessive anthropogenic nutrient loading is a major threat worldwide, and especially in estuaries and semi-enclosed waterbodies, like the brackish Baltic Sea. In addition, coastal waters may become darker (coastal darkening) due to increased input of colored compounds from terrestrial run-off and sediment resuspension. Still, the effects of darkening on coastal food w

The real Ginzburg–Landau equation arises as a universal amplitude equation for the description of pattern-forming systems exhibiting a Turing bifurcation. It possesses spatially periodic roll solutions which are known to be stable against localized perturbations. It is the purpose of this paper to prove their stability against bounded perturbations, which are not necessarily localized. Since all s

Background: Autoimmune diseases are associated with many cancers but there is a lack of population-based studies with different autoimmune diseases that have a long follow-up. This is also true of hepatobiliary cancers, which include hepatocellular cancer (HCC) and rarer entities of gallbladder cancer (GBC), intra- and extrahepatic cholangiocarcinoma (iCCA and eCCA), and ampullary cancer. Methods:

PURPOSE: This study aimed to examine the associations between the intake of high- and low-fat fermented dairy (cheese and fermented milk), their proteomic profiles, and mortality risk.METHODS: This cohort study included 25,187 participants (mean age 57.7 years, 60.9% females). Fermented dairy intake was assessed by a modified diet history method. In a random subset of this cohort (n = 4359), we co

OBJECTIVE: Autoantibodies have long been recognized as biomarkers of islet autoimmunity in type 1 diabetes, but their role in the pathogenesis is not fully understood. The aim of this study was to analyze clinical and hereditary characteristics of children presenting with and without autoantibodies at type 1 diabetes diagnosis.RESEARCH DESIGN AND METHODS: Data were collected from children (<18 yea

The Iberian ribbed newt (Pleurodeles waltl) constitutes a central model for probing the basis of vertebrate regeneration. Here, we present the sequencing and chromosome-scale assembly of the 20.3Gb P. waltl genome, which exhibits the highest level of contiguity and completeness among giant genome assemblies. We uncover that DNA transposable elements are the major contributors to its expansion, wit

Nanowires have an ideal shape for high-resolution imaging, with a small cross-section for high resolution and a long length for strong absorption. However, since the absorption in nanowires is dominated by nanophotonic effects, it is unclear what resolution and efficiency such devices could offer. Here, we investigate the limits of spatial resolution and efficiency of nanowire-based direct detecto

Objectives: Menstrual migraine (MM) is a debilitating neurological disorder triggered by fluctuations in ovarian hormones, particularly estrogen. While the calcitonin gene-related peptide (CGRP) system is central to migraine pathophysiology, the molecular mechanisms linking hormonal changes to CGRP signaling remain unclear. This study investigates how sex hormones regulate CGRP-related gene expres

Denna uppsats undersöker hur EU:s konkurrenslagstiftning reglerar interoperabilitetsskyldigheter för dominerande digitala plattformar. Uppsatsen visar hur EU-domstolens avgörande i Android Auto (C-233/23) omformar teorin om nödvändiga nyttigheter (Essential Facilities Doctrine, EFD) som etablerades i Bronner-domen (C-7/97). Vidare analyseras denna framväxande doktrins samspel med de interoperabiliThis thesis explores how EU competition law governs interoperability obligations for dominant digital platforms. It shows how the CJEU’s judgment in Android Auto (C-233/23) redefines the Essential Facilities Doctrine (EFD) established in Bronner judgment (C-7/97) and how this emerging doctrine interacts with the interoperability obligations introduced by the Digital Markets Act (DMA). The Android

Under uppsvinget av corona pandemin år 2020 läarde vi att anpassa oss till förändrade förutsättningar i samhället till större grad än tidigare. Forskare och företag världen över samarbetade för att utveckla och producera ett vaccin som skulle minska spridningen av viruset. Idag är denna pandemin nästan ett minne blott tack vare messengerRNA (mRNA)-vaccin, som har revolutionerat leverandet av mRNA Lipid nanoparticles (LNPs) are vesicular structures composed of phospholipids commonly used in vaccine formulations due to their ability to protect and encapsulate mRNA for efficient delivery to target cells. This delivery system was pivotal for the rapid development of COVID-19 mRNA vaccines. Efficient mRNA delivery depends on the particle size and stability of LNPs, making these key parameters t