Transport and mobility systems need to be transformed to meet climate change goals and reduce negative environmental and social effects. Despite EU policies having targeted such problems for more than three decades, transitions have been slow and geographically uneven. For effective change to happen, transport and mobility research needs fresh perspectives and better integration of knowledge from

Osteoarthritis (OA) is a common musculoskeletal disease that leads to deterioration of articular cartilage, joint pain, and decreased quality of life. When OA develops after a joint injury, it is designated as post-traumatic OA (PTOA). The etiology of PTOA remains poorly understood, but it is known that proteoglycan (PG) loss, cell dysfunction, and cell death in cartilage are among the first signs

Leaching behaviour is an important evidence of soil quality. The assessment of leaching of heavy metals from the contaminated soil is vital for environmental applications. However, leaching may differ in soil stabilised by various ratios of binders. In this study we measured leaching behaviour of soil contaminated by As, Cd, Co, Cr, Cu, Hg, Ni, Pb, V, Zn, methyl Hg, aliphatic compounds of hydrocar

Introduction: This study investigated the comparability of cerebrospinal fluid (CSF) cutoffs for Elecsys immunoassays for amyloid beta (Aβ)42/Aβ40 or Aβ42/phosphorylated tau (p-tau)181 and the effects of measurement variability when predicting Alzheimer's disease (AD)-related outcomes (i.e., Aβ-positron emission tomography [PET] visual read and AD neuropathology). Methods: We studied 750 participa

In computer-vision feature extraction algorithms, compressing the image into a sparse set of trackable keypoints, empowers navigation-critical systems such as Simultaneous Localization And Mapping (SLAM) in autonomous robots, and also other applications such as augmented reality and 3D reconstruction. Most of those applications are performed in battery-powered gadgets featuring in common a very st

Background: Most studies on long-term follow-up of patients with COVID-19 focused on hospitalised patients. No prospective study with structured follow-up has been performed in non-hospitalised patients with COVID-19. Objectives: To assess long-COVID and post-COVID (WHO definition: symptomatic at least 12 weeks), describe lingering symptoms, their impact on daily activities, and general practice v

Background: Previous research suggests that interactions between preschool teachers and children in early care and educational contexts can contribute to the child’s positive attachment development and socioemotional adjustment. Objective: Investigate how the transition process to preschool is organized and whether various ways of organizing it may differently influence family–teacher relationship

Aims. Stars with strong enhancements of r-process elements are rare and tend to be metal-poor, generally with [Fe/H] < -2 dex, and located in the halo. In this work, we aim to investigate a candidate r-process enriched bulge star with a relatively high metallicity of [Fe/H] ~ -0.65 dex and to compare it with a previously published r-rich candidate star in the bulge. Methods. We reconsidered the ab

People that produce bad outcomes can thereby become the fitting targets of blame, the fitting intensity of which is determined by the badness of the outcomes. In the following paper, I suggest that the amount of blame instances that people are fitting targets of is also determined by the weight of the badness of the outcomes. I use the example of online blame as a paradigmatic case where the amoun

MK-801, also called dizocilpine, is an N-methyl-D-aspartate (NMDA) receptor antagonist widely used in animal research to model schizophrenia-like phenotypes. Although its effects in rodents are well characterised, little is known about the outcomes of this drug in other organisms. In this study, we characterise the effects of MK-801 on the locomotion, sleep, and negative geotaxis of the fruit fly

Context. The solar vicinity is currently populated by a mix of stars with various chemo-dynamic properties, including stars with a high metallicity compared to the Sun. Dynamical processes such as churning and blurring are expected to relocate such metal-rich stars from the inner Galaxy to the solar region. Aims. We report the identification of a set of old super-metal-rich (+0.15 ≤ [Fe/H] ≤ +0.50

Context.Gaia's third data release provides radial velocities for 33 million stars and spectroscopically derived atmospheric parameters for more than 5 million targets. When combined with the astrometric data, these allow us to derive orbital and stellar parameters that are key to understanding the stellar populations of the Milky Way and to perform Galactic archaeology. Aims. We used the calibrate

Context. The high quality of the Gaia mission data has allowed for studies of the internal kinematics of the Large Magellanic Cloud (LMC) to be undertaken in unprecedented detail, providing insights into the non-axisymmetric structure of its disc. Recent works by the Gaia Collaboration have already made use of the excellent proper motions of Gaia DR2 and Gaia EDR3 for a first analysis of this sort

Seaweeds (macroalgae) are gaining attention as potential sustainable feedstock for the production of fuels and chemicals. This comparative study focuses on the characterization of the microbial production of alcohols from fermentable carbohydrates in the hydrolysate of the macroalgae Laminaria digitata as raw material. The potential of a hydrolysate as a carbon source for the production of selecte

Fungal tracheobronchitis caused by Aspergillus and Candida spp. is a recognized complication after lung transplantation, but knowledge of the incidence of Candida tracheobronchitis is lacking. The diagnosis relies on fungal cultures in bronchoalveolar lavage fluid (BALF), but cultures have low specificity. We aimed to evaluate the one-year incidence of fungal tracheobronchitis after lung transplan

Background: Fibroblast-like synoviocytes (FLSs) are essential mediators in the expansive growth and invasiveness of rheumatoid synovitis, and patients with a fibroblastic-rich pauci-immune pathotype respond poorly to currently approved antirheumatic drugs. Galectin-9 (Gal-9) has been reported to directly modulate rheumatoid arthritis (RA) FLSs and to hold both pro- and anti-inflammatory properties

Fire strongly impacts the composition and structure of ecosystems, with consequences yet to be understood. We used Moderate Resolution Imaging Spectroradiometer (MODIS) data to map fire frequency and fire intensity and investigate their effects on miombo woodlands (MW) of central Mozambique. Tree species diversity was evaluated and compared using rarefaction curves. Non-metric multidimensional sca

International lawyers ascribe to the lex specialis principle three distinctly different meanings. Thus, lex specialis is referred to, first, as a norm designed to resolve conflicts between entire categories of norms; secondly, as a norm designed to resolve conflicts on a case-by-case basis; and, thirdly, as a rule of interpretation designed to avoid the occurrence of normative conflicts, rather th