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IA-2 autoantibodies in incident type I diabetes patients are associated with a polyadenylation signal polymorphism in GIMAP5.

In a large case-control study of Swedish incident type I diabetes patients and controls, 0–34 years of age, we tested the hypothesis that the GIMAP5 gene, a key genetic factor for lymphopenia in spontaneous BioBreeding rat diabetes, is associated with type I diabetes; with islet autoantibodies in incident type I diabetes patients or with age at clinical onset in incident type I diabetes patients.

Adoption of ITS for dangerous goods road transportation – a review and research agenda

ad transport of dangerous goods is due to its inherent risk associated with a potential impact far higher than the small volumes might suggest, and has therefore been the target of numerous ITS-related initiatives. However, there are few indications of actual working ITS solutions for dangerous goods. In this paper we conduct an empirical investigation of past projects and research to analyze the

GARD - Genomic Allergen Rapid Detection. A Testing Strategy for Assessment of Chemical Sensitizers

Popular Abstract in Swedish Vi lever i en tid och i ett samhälle där kemikalier har blivit en naturlig del av vår industrialiserade vardag. Till stor del ligger kemikalieindustrin bakom flera av de stora tekniska framsteg som gör att västvärlden har den levnadsstandard den idag har. Tyvärr har den stora spridningen av icke naturligt förekommande kemikalier ibland också negativa effekter både på miThe modern world is increasingly dependent of the use of chemicals. The chemical industries have greatly contributed to the high standard of living in industrialised societies, and chemical compounds surround us in everyday life. Unfortunately, a vast number of chemicals cause adverse effects on the environment and human health. One such concern is chemical hypersensitivity, which is a state cause

Immunsvar och inflammation vid Crohns sjukdom. Snart mojligt driva diagnostiken langre och utveckla mer specifika lakemedel

The chronic inflammation in Crohn's disease may be caused by aggressive response to bacterial antigens normal to the gut. Genetic and environmental factors modify the inflammatory response evoked by damage to the mucosal gut barrier. Genetic factors may also determine the subsequent course of chronic inflammation. Further elucidation of the pathogenesis might improve our understanding of the heter