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Majorana modes in quantum dots coupled via a floating superconducting island

Majorana modes can be engineered in arrays where quantum dots (QDs) are coupled via grounded superconductors, effectively realizing an artificial Kitaev chain. Minimal Kitaev chains, composed by two QDs, can host fully localized Majorana modes at discrete points in parameter space, known as Majorana sweet spots. Unlike grounded superconductors, where the superconducting phase is a conserved quantu

Reversible excited state electron transfer in an acceptor-acceptor hetero dyad

In this manuscript, we create a new hetero dyad consisting of two electron acceptors with nearly isoenergetic HOMO and LUMO levels, namely perylene diimide (PDI) and aza dioxa triangulenium (ADOTA). This dyad system displays an unusual and reversible excited state electron transfer process. Upon excitation, the dyad shows complete energy transfer from the locally excited PDI to the ADOTA moiety in

Folate-Associated Gene Expression in Primary Tumors Is Associated With Tumor Response and Progression-Free Survival of Patients With Metastatic Colorectal Cancer Undergoing 5-FU/Leucovorin-Based Combination Chemotherapy

Background: 5-Fluorouracil (5-FU) and the Folate Leucovorin (LV) form the chemotherapy backbone for metastatic colorectal cancer (mCRC). Tumoral expression of specific folate-associated genes is associated with the risk of recurrence in stage III CRC following adjuvant 5-FU/LV (FLV)-based combination chemotherapy according to the Nordic bolus regimen. The aim was to evaluate whether expression of

Survival Differences between Individuals with Typical and Atypical Phenotypes of Alzheimer Disease

Background and ObjectivesSurvival estimates for individuals with Alzheimer disease (AD) are informative to understand the disease trajectory, but precise estimates for atypical AD variants are scarce. Atypical AD variants are characterized by nonamnestic phenotypes, an early onset, and lower prevalence of APOEϵ4 carriership, which affect the AD trajectory. We aimed to provide survival estimates fo

Pb-intercalated epitaxial graphene on SiC : Full insight into band structure and orbital character of interlayer Pb, and charge transfer into graphene

Intercalation is a robust approach for modulating the properties of epitaxial graphene on SiC and stabilizing two-dimensional intercalant layers at the graphene/SiC interface. In this paper, we present synchrotron-based angle resolved photoelectron spectroscopy (ARPES) measurements focusing on the band structure of intercalated Pb under a single layer of epitaxial graphene. The interlayer Pb exhib

Leptin and PAI-1 Levels Are Decreased After a Dietary Intervention in Patients with Irritable Bowel Syndrome

A diet low in fermentable oligo-, di-, and monosaccharides and polyols (FODMAP) is an established treatment for irritable bowel syndrome (IBS). The starch- and sucrose-reduced diet (SSRD) is a newer, promising diet. Nutrients influence the production of gut hormones, which affect gastrointestinal motility. This study aimed to investigate the changes in copeptin, leptin, PAI-1, C-peptide, and insul

Analogical reasoning : a Carnapian approach

Analogical reasoning is a form of non-deductive reasoning that gives special weight to similarity considerations. Here, we pursue an approach to formalizing this type of reasoning that was initiated by Carnap in posthumously published work. In it, Carnap abandoned his long-time project of trying to define inductive and analogical reasoning syntactically and introduced attribute spaces to model the

High diversity of nitrifying bacteria and archaea in biofilms from a subsea tunnel

Microbial biofilm formation can contribute to the accelerated deterioration of steel-reinforced concrete structures and significantly impact their service life, making it critical to understand the diversity of the biofilm community and prevailing processes in these habitats. Here, we analyzed 16S rRNA gene amplicon and metagenomics sequencing data to study the abundance and diversity of nitrifier

Entangled in context : addressing academic development and educational choice architecture

This paper describes the evaluation of newly created pedagogical programs for early-career educators delivered by academic developers (ADs) in two universities in Central Europe. Initially conceived as an evaluation of the program’s effectiveness, iterative analysis led to acknowledgment of the importance of context for the impact of these programs. We recognize prevalent educational choice archit

TOI-3493 b : A planet with a Neptune-like density transiting a bright G0-type star

We report the discovery of TOI-3493 b, a sub-Neptune-sized planet on an 8.15-d orbit transiting the bright (V=9.3) G0 star HD 119355 (aka TIC 203377303) initially identified by NASA's TESS space mission. With the aim of confirming the planetary nature of the transit signal detected by TESS and determining the mass of the planet, we performed an intensive Doppler campaign with the HARPS spectrograp

Exclusion of Disperse Orange 3 From the Textile Dye Mix Present in the Baseline Patch-Test Series : A Study by the International Contact Dermatitis Research Group

Background: The textile dye mix (TDM) 6.6% in petrolatum contains Disperse Blue (DB) 35, Disperse Yellow 3, Disperse Orange (DO) 1 and 3, Disperse Red 1 and 17, and DB 106 and 124. The most frequent allergen in TDM-positive patients is DO 3. Around 85% of para-phenylenediamine (PPD)-allergic dermatitis patients have been positive to DO 3. There has been a discussion to exclude DO 3 from TDM 6.6% b

Hydrogen migration reactions via low internal energy pathways in aminobenzoic acid dications

Hydrogen migration is a ubiquitous phenomenon upon dissociation of organic molecules. Here we investigate the formation of a H3O+ fragment after core-level photoionization and Auger decay in aminobenzoic acid molecules - a process that requires the migration of at least two hydrogen atoms. Using photoelectron-photoion coincidence spectroscopy, the formation of a H3O+ fragment is observed to be mor

Feasibility, safety and patient perceptions of exercise-based cardiac telerehabilitation in a multicentre real-world setting after myocardial infarction—the remote exercise SWEDEHEART study

Aims Cardiac telerehabilitation addresses common barriers for attendance at exercise-based cardiac rehabilitation (EBCR). Pragmatic real-world studies are however lacking, limiting generalizability of available evidence. We aimed to evaluate feasibility, safety, and patient perceptions of remotely delivered EBCR in a multicentre clinical practice setting after myocardial infarction (MI). Methods a

Transnational labour governance in hazelnut value chain : farmers and seasonal migrant workers at the nexus of market and politics in Turkey

This article combines insights from two emerging literatures on transnational private regulation: the grounding perspective and politics and power in global value chains. Drawing on a case study conducted in Turkey, it examines political economy of voluntary sustainability standards in hazelnut production, a critical but overlooked part of the chocolate value chain with no shortage of human rights

Intrinsic three-dimensional topology in SrNbO3 films

Transition metal oxides, with their wide range of electronic and magnetic properties, offer a remarkable platform for developing future electronics based on unconventional quantum phenomena, such as topological phases. The formation of topologically nontrivial states is linked to crystalline symmetry, spin-orbit coupling, and magnetic ordering. Here, by employing angle-resolved photoemission spect

Precision nutrition for cardiometabolic diseases

Precision nutrition is a vibrant and rapidly evolving field of scientific research and innovation with the potential to deliver health, societal and economic benefits by improving healthcare delivery and policies. Advances in deep phenotyping technologies, digital tools and artificial intelligence have made possible early proof-of-concept research that expands the understanding of within- and betw

“This is something we live through every day” : negotiating the cultural memory of the Decembrist revolt in Russian historical film Union of Salvation

The study examines the narratives of the Decembrist revolt created in and around Russian state-funded cinema. By exploring the narratives surrounding a particular instance of political dissent in the past, the research seeks to uncover the factors that impact on the negotiation of cultural memory between the text and the audience in the context of state-influenced media. This exploration is based

Long COVID clinical evaluation, research and impact on society : a global expert consensus

Background: Long COVID is a complex, heterogeneous syndrome affecting over four hundred million people globally. There are few recommendations, and no formal training exists for medical professionals to assist with clinical evaluation and management of patients with Long COVID. More research into the pathology, cellular, and molecular mechanisms of Long COVID, and treatments is needed. The goal of

Transphobia : A ”New Antisemitism”

In this paper, I explore similarities and differences between contemporary transphobic and anti-Jewish discourses. While scholars have shown entanglements between homophobic and antisemitic discourses in the European 19th century, as well as similarities between contemporary homonationalist and Western philosemitic discourses, less attention has been paid to how anti-trans and anti-Jewish discours

Dynamic Interference of Chirped Photoelectrons

Dynamic interference is an elusive strong-field effect where photoelectrons from intense laser pulses interfere in time, forming rich kinetic energy patterns. Here, we present the first experimental demonstration of isolated dynamic interference using a novel two-color scheme: chirped laser-assisted dynamic interference. Isolation was achieved with a crossed-polarization setup combining an extreme