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Invisible, Responsible Women in Sweden–Planning Pregnancies, Choosing Contraceptives

In this study I explore discourses of contraception and reproduction, which are drawn upon and reproduced in Swedish official online sources on contraceptive advice, through the theoretical frameworks of biomedicalization and reproductive justice. The analysis yielded three interwoven themes: 1) women in need of contraceptives have to balance discourses of exogenous hormones as both an “unnatural”

Software compatibility analysis for quantitative measures of [18F]flutemetamol amyloid PET burden in mild cognitive impairment

Rationale: Amyloid-β (Aβ) pathology is one of the earliest detectable brain changes in Alzheimer’s disease pathogenesis. In clinical practice, trained readers will visually categorise positron emission tomography (PET) scans as either Aβ positive or negative. However, adjunct quantitative analysis is becoming more widely available, where regulatory approved software can currently generate metrics

Using the auditory brainstem response elicited by within-channel gaps to measure temporal resolution

The Auditory Brainstem Response (ABR) can be used to measure the early temporal activity of the auditory system. A gapin- noise ABR has been developed to measure the electrophysiological response to auditory stimulation without attending to the task. In the present study, young adults passively listened to stimuli of various gap widths in separate sequences. In a single sequence, two identical 15

In vivo assessment of elbow flexor work and activation during stretch-shortening cycle tasks

The purpose of this study was to use an electromyography (EMG) based muscle model to investigate the performance enhancement of stretch-shortening cycle (SSC) tasks at different elbow flexion-extension velocities. A torque motor was used to oscillate the forearms of seven healthy male subjects (23-40 years) during SSC and non-SSC contractions at four frequencies of movement (.58, 1.5, 2.4 and 3.3

Altered postural control during the luteal phase in women with premenstrual symptoms

The purpose of this study was to investigate postural control in women with and without premenstrual symptoms (PMS) in three hormonally verified phases of the menstrual cycle. Thirty-two women were recruited to participate in the study and 25 of these women were included in the results. Menstrual cycle phases were determined by sex hormone analyses in serum and LH detection in urine. A prospective

Sex differences in muscle activation patterns associated with anterior cruciate ligament injury during landing and cutting tasks : A systematic review

Neuromuscular control is critical for maintaining dynamic joint stability and mitigating the risk of anterior cruciate ligament (ACL) injury. Given the increased risk of ACL injury in females, sex-based differential muscle activation strategies are often associated with this risk. For example, the quadriceps-dominant muscle activation strategy sometimes observed in females has been discussed as a

A hierarchy in functional muscle roles at the knee is influenced by sex and anterior cruciate ligament deficiency

Background: Sex-related neuromuscular differences have been linked to greater risk of anterior cruciate ligament injuries in females. Despite this, it remains unclear if sex-related differences are present after injury. This study sought to determine if sex differences are present in the functional roles of knee joint muscles in an anterior cruciate ligament deficient population. Methods: An isome

Experimental muscle pain of the vastus medialis reduces knee joint extensor torque and alters quadriceps muscle contributions as revealed through musculoskeletal modeling

Background: Voluntary activation deficit of the quadriceps muscle group is a common symptom in populations with knee joint injury. Musculoskeletal modeling and simulations can improve our understanding of pathological conditions; however, they are mathematically complex which can limit their clinical application. A practical subject-specific modeling framework is introduced to evaluate knee extens

Neuromuscular adaptations in older males and females with knee osteoarthritis during weight-bearing force control

Background: Females exhibit significantly greater incidence, prevalence, and severity of osteoarthritis (OA) compared to males. Despite known biological, morphological, and functional differences between males and females, there has been little sex-related investigation into sex-specific biomechanical and neuromuscular responses to OA. Objective: To identify sex-related differences in OA-affected

Divergence analysis of failed and successful unanticipated single-leg landings reveals the importance of the flight phase and upper body biomechanics

The purpose of this study was to describe neuromuscular and kinematic differences during failed and successful drop-vertical jumps in a pediatric population. Healthy young athletes (n = 32) completed single-leg drop vertical jump landings where the required landing leg was unanticipated. Trials were categorized as failed if the participant shifted their base of support during the landing. Joint ki

Effect of alpine ski boot cuff release on knee joint force during the backward fall

The modern rigid alpine ski boot has been associated with an increase in severe knee joint injuries. A new design that allows the rear portion of the upper cuff of the boot (rear spoiler) to open when a posterior directed force is applied to it (similar to when a skier falls back on the ski) is investigated. Motion analysis was combined with kinetic measures to estimate the shear and compressive f

The clinical significance of electromyography normalisation techniques in subjects with anterior cruciate ligament injury during treadmill walking

This study investigated the clinical interpretation of three electromyographic (EMG) normalisation techniques to detect neuromuscular alterations in patients diagnosed with anterior cruciate ligament knee injury during treadmill walking. The EMG signal was normalised using the mean value during the gait cycles (MEA), the maximum value during the gait cycles (MAX), and a maximum voluntary isometric

Sex-related differences in neuromuscular control : Implications for injury mechanisms or healthy stabilisation strategies?

Sex-related differences in neuromuscular activation have been previously identified and are thought to be an underlying contributor to the ACL injury mechanism. During dynamic tasks evaluating the role of muscle action as it relates to joint stability is difficult since individual muscle contributions to force generation are confounded by biomechanical factors of movement. The purpose of this stud

Auditory brainstem responses in tinnitus : A review of who, how, and what?

The auditory brainstem response (ABR) in tinnitus subjects has been extensively investigated over the last decade with the hopes of finding possible abnormalities related to the pathology. Despite this effort, the use of the ABR for tinnitus diagnosis or as an outcome measure is under debate. The present study reviewed published literature on ABR and tinnitus. The authors searched PubMed, MedLine,

Decision Tree Learning Algorithm for Classifying Knee Injury Status Using Return-to-Activity Criteria

Anterior cruciate ligament (ACL) injury rates in female adolescents are increasing. Irrespective of treatment options, approximately 1/3 will suffer secondary ACL injuries following their return to activity (RTA). Despite this, there are no evidence-informed RTA guidelines to aid clinicians in deciding when this should occur. The first step towards these guidelines is to identify relevant and feas

Standardization proposal of soft tissue artefact description for data sharing in human motion measurements

Soft tissue artefact (STA) represents one of the main obstacles for obtaining accurate and reliable skeletal kinematics from motion capture. Many studies have addressed this issue, yet there is no consensus on the best available bone pose estimator and the expected errors associated with relevant results. Furthermore, results obtained by different authors are difficult to compare due to the high v

Validation of knee joint models - An in vivo study

The effect of modeling the knee as a simple spherical or revolute joint during gait, cutting and hopping were evaluated. The results indicate that, even during gait, a revolute joint may be too restrictive in its representation of the knee, with flexion/extension errors as high as 9.4°. By imposing the spherical joint, joint angles showed consistent and strong correlations with the true joint angl

Predicting post-operative functional ability from pre-operative measures in ACL-injured individuals

Purpose: This study aimed to quantify the relationship between objective and subjective measures of functional ability and determine if measures in the deficient (ACLd) state were correlated to, and capable of predicting a patient's objective and subjective measures in the reconstructed (ACLr) state. Methods: Twenty ACL-injured participants completed hop and side cut movements prior to and 10 mont

Use of muscle synergies and wavelet transforms to identify fatigue during squatting

The objective of this study was to supplement continuous wavelet transforms with muscle synergies in a fatigue analysis to better describe the combination of decreased firing frequency and altered activation profiles during dynamic muscle contractions. Nine healthy young individuals completed the dynamic tasks before and after they squatted with a standard Olympic bar until complete exhaustion. El