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While recent experimental frameworks for national ecosystem service accounting have shown substantial progress, in our view some crucial methodological issues remain that deserve further consideration before setting final standards. In response to the landmark work of Obst et al. (Environ Resour Econ 64:1–23, 2016. doi: 10.1007/s10640-015-9921-1), we provide arguments with regard to the suitabilit
The Green Economy is a strategic development concept of the United Nations incorporating a broad array of potential meanings and implications. It is subject to academic conceptualisation, operationalisation, reflection and criticism. The aim of our paper is to conceptualise a subset of the multi-faceted and at times polarised debate around the implications and applications of the Green Economy con
Study Design: Qualitative study. Introduction: An amputation injury to the hand may lead to not only impaired hand function but also psychosocial consequences. Purpose of the Study: The purpose of the study was to explore personal experiences of social participation for persons provided with an esthetic prosthesis after acquired upper limb amputation. Methods: Thirteen persons with acquired upper
Climate‐warming induced permafrost thaw exposes large amounts of carbon and nitrogen in soil at greater depths below the seasonally‐thawing active layer. The extent to which plant roots can reach and interact with these hitherto detached, deep carbon and nitrogen stores remains unknown. We aimed to quantify how permafrost thaw affects root dynamics across soil depths and plant functional types com
Background: Deep learning convolutional neural networks (CNN) may facilitate melanoma detection, but data comparing a CNN's diagnostic performance to larger groups of dermatologists are lacking.Methods: Google's Inception v4 CNN architecture was trained and validated using dermoscopic images and corresponding diagnoses. In a comparative cross-sectional reader study a 100-image test-set was used (l
In their most extreme form, sex chromosomes exhibit a complete lack of genetic recombination along much of their length in the heterogametic sex. Some recent models explain the evolution of such suppressed recombination by the "sheltering"of deleterious mutations by chromosomal inversions that prevent recombination around a polymorphic locus controlling sex. This sheltering hypothesis is based on
The Schmidt number represents the genuine entanglement dimension of a bipartite quantum state. We derive simple criteria for the Schmidt number of a density matrix in arbitrary local dimensions, given that certain symmetric measurements exist. They are based on the trace norm of correlations obtained from seminal families of quantum measurements, specifically symmetric informationally complete mea
The glycosaminoglycan dermatan sulfate (DS) is a well-known activator of heparin cofactor II-dependent inactivation of thrombin. In contrast to heparin, dermatan sulfate has never been prepared recombinantly from material of non-animal origin. Here we report on the enzymatic synthesis of structurally well-defined DS with high anticoagulant activity. Using a microbial K4 polysaccharide and the reco
Objective To investigate the relation between preterm birth (gestational age <37 weeks) and risk of CKD from childhood into mid-adulthood. Design National cohort study. Setting Sweden. Participants 4 186 615 singleton live births in Sweden during 1973-2014. Exposures Gestational age at birth, identified from nationwide birth records in the Swedish birth registry. Main outcome measures CKD, identif
Change in Japanese foreign and security policy has long been characterized as “incremental”. However, Japan’s response to Russia’s 2022 invasion of Ukraine provides an opportunity to reconsider this paradigm. In the aftermath of the 2014 annexation of Crimea, then-Prime Minister Abe Shinzō chose not to put Crimea on the agenda, prioritizing instead relations with Russia. However, Prime Minister Ki
Business implications of the recent surge in populism in societal and academic discourse have been relatively neglected. This is surprising, considering that corporations provide financial support (e.g., donations and political action committees), intellectual resources (e.g., think tanks and public relations firms) and informational channels (e.g., social media platforms) that populist parties an
BACKGROUND: There is a well-known comorbidity between chronic obstructive pulmonary disease (COPD) and coronary artery disease (CAD) which is only partially explained by common risk factors. Markers of cardiovascular autonomic dysfunction (CVAD), such as orthostatic hypotension and increased resting heart rate, are strongly associated with CAD. The autonomic nervous system also innervates the airw
Objective Systemic sclerosis Impact of Disease (ScleroID) is the first comprehensive patient-reported outcome measure (PROM) specifically developed for systemic sclerosis (SSc). We investigated the performance of ScleroID in patients with diffuse cutaneous SSc (dcSSc), as a prerequisite for its use in randomised controlled trials (RCTs) testing potentially disease-modifying drugs. Methods All pati
Background: Therapy directed at the central nervous system (CNS) is an essential part of the treatment for childhood acute lymphoblastic leukemia (ALL). The current evaluation of CNS involvement based on cytomorphological examination of the cerebrospinal fluid (CSF) alone is not as sensitive with low cell counts as flow cytometric immunophenotyping (FCI) of the CSF. However, the importance of low
Background: High-sensitivity assays for cardiac troponin T (hs-cTnT) are sometimes used to rapidly rule out acute myocardial infarction (AMI).Purpose: To estimate the ability of a single hs-cTnT concentration below the limit of detection (<0.005 µg/L) and a nonischemic electrocardiogram (ECG) to rule out AMI in adults presenting to the emergency department (ED) with chest pain.Data Sources: EMBASE
This paper seeks to determine the decision-making route relating to hedonic and environmental motivation in green innovation adoption and to show how two similar green innovations can motivate consumers differently. It also aims to determine the effect of domain-specific innovativeness (DSI) on emotions and green identity on environmental motivations. The paper focuses on two types of green transp
Hypothesis: Self-assembly of amphipathic styrene maleic acid copolymers with phospholipids in aqueous solution results in the formation of ‘nanodiscs’ containing a planar segment of phospholipid bilayer encapsulated by a polymer belt. Recently, studies have reported that lipids rapidly exchange between both nanodiscs in solution and external sources of lipids. Outstanding questions remain regardin
Fluorescently-labelled variants of poly(styrene-co-maleic acid), SMA, have been synthesised by RAFT copolymerisation. We show that low ratios of vinyl fluorophores, analogous to styrene, can be successfully incorporated during polymerisation without detriment to nanodisc formation upon interaction with lipids. These novel copolymers are capable of encapuslating lipids and the model membrane protei
A continuous rotary membrane emulsification (cRME) system, allowing the decoupling of droplet generation from continuous phase (CP) flowrate, is presented here for the first time. The decoupling results in higher productivity and greater control compared to traditional crossflow and rotational membrane emulsification processes. A design of experiment (DoE) investigated the influence on droplet for
