Human C4b-binding protein (C4BP) is a soluble, multiple-subunit inhibitor of complement that circulates in blood. Recently C4BP was shown to bind DNA, reduce DNA release from necrotic cells and limit DNA-mediated complement activation in solution. Herein we employed nuclear magnetic resonance spectroscopy to measure chemical shift perturbations and used them to restrain the computational docking o

General introduction to the poetry and the verse novels by Australian writer Dorothy Porter

EG-kommissionen har sedan 1997 arbetat med att revidera den europeiska konkurrensrätten och anpassa den till ny ekonomisk teori. Moderniseringen har lett till att regelverket förtydligats genom det vertikala gruppundantaget (1999), de horisontella gruppundantagen (2001) och bildistributionsundantaget (2002). En revision av 1996 års teknikförordning ligger i tiden. Även procedurreglerna genomgår ge

BACKGROUND: Laminin alpha2 chain mutations cause congenital muscular dystrophy with dysmyelination neuropathy (MDC1A). Previously, we demonstrated that laminin alpha1 chain ameliorates the disease in mice. Dystroglycan and integrins are major laminin receptors. Unlike laminin alpha2 chain, alpha1 chain binds the receptors by separate domains; laminin globular (LG) domains 4 and LG1-3, respectively

Artikeln undersöker vad bestämmelsen om Sveriges EU-medlemskap och om internationellt samarbete i 1 kap. 10 § regeringsformen betyder rättsligt för den offentliga förvaltningen, särskilt avseende socialförsäkringsrätten och Försäkringskassan. En bakgrund till bestämmelsen är internationaliseringen av den offentliga rätten. Utvecklingen har inneburit att en stor del av de normer som svenska myndigh

The success of most software companies depends largely on software product quality. High product quality is usually a result of advanced software development processes. Hence, improvement actions should be selected based on sound knowledge about the dependencies between software product quality attributes and software development processes. This article describes a method for developing product/pr

The radiative lifetimes of the states in the (n=5-8) 3snp P-1(1) sequence of neutral magnesium were investigated using time-resolved laser-induced fluorescence. Excitation from the 3s2 S-1(0), ground state was performed using VUV radiation, which was produced by resonant sum-difference frequency mixing in a krypton gas cell. We find tau(n=5): 54(3) ns, tau(n=6): 140(10) ns, tau(n=7): 290(20) ns, t

Short article on the relationship between the mysticism and inherent poetics of Emanuel Swedenborg, and ideas about materiality and corporeality