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Biological significance of ECL-cell histamine

In the oxyntic mucosa of the mammalian stomach, histamine is stored in enterochromaffin-like (ECL) cells and in mucosal mast cells. The activity of the histamine-forming enzyme, histidine decarboxylase (HDC), is high in ECL cells but lower in the mucosal mast cells. We studied the consequences of depleting ECL-cell histamine by continuous infusion of the HDC inhibitor a-fluoromethylhistidine (a-FM

A Pilot Investigation of Cognitive Therapy for Generalized Anxiety Disorder in Children Aged 7–17 Years

The development of treatments based on cognitive models of worry has led to improved outcomes for adults with Generalized Anxiety Disorder (GAD), and holds out the promise that similar improvements may be achieved for GAD further down the age range. The aim of the current study was to evaluate the effect of a GAD specific,cognitive treatment in a sample of children and adolescents with GAD. Sixtee

Building semantic editors using JastAdd: tool demonstration

A semantic editor, providing services like completion and code browsing, can help users to quickly develop high-quality source code. However, a lot of languages still lack semantic editor support due to the difficulty and costs of development. Tool generation and reuse can greatly alleviate this development task. Specifically, tool generation from a formal specification, such as reference attribut

The Nom/Acc alternation in Germanic

This paper describes the distribution of accusative case and discusses the nature of the nominative / accusative distinction in the standard Germanic languages. In addition, it illustrates and discusses the well-known fact that inherent accusatives and certain other types of accusatives do not behave in accordance with Bruzio’s Generalization. In spite of these Non-Burzionian accusatives, there is

Cross-Germanic Promotion to Subject in Ditransitive Passives – a Feature-Driven Account

Languages differ with respect to which element they select as the subject in passive of ditransitive verbs: either the active indirect object (the goal argument) or the active direct object (the theme argument). In standard American English, e.g., only the goal argument may be promoted, as shown by the difference between (1b) and (1c). (1) a. John gave Mary a red bike yesterday. b. Mary was give