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BACKGROUND: Among infants with isolated cleft palate, whether primary surgery at 6 months of age is more beneficial than surgery at 12 months of age with respect to speech outcomes, hearing outcomes, dentofacial development, and safety is unknown. METHODS: We randomly assigned infants with nonsyndromic isolated cleft palate, in a 1:1 ratio, to undergo standardized primary surgery at 6 months of ag
Concern for the health of the natural environment is growing as humanpopulation grows. Recently, renewed attention has been given to the environmentalimpact of fires and the fire implications of sustainability choices made in the builtenvironment. To properly understand the environmental impact of fires, however, itis crucial that we can estimate fire emissions. This paper explores the concept of
This thesis explores the physics of nanostructures involving nanowires, quantum dots, superconductors, and topological insulators. These systems serve as excellent platforms for fundamental physics studies and quantum technology applications.The introduction contains information on the band structures of crystalline materials and transport phenomena in quantum dots. It is followed by discussions o
Interactions of lipid vesicles play important roles in a large variety of functions and dysfunctions in the human body. Vital for several biochemical functions is the interaction between monomeric proteins and lipid membranes, and the induced phenomena such as fusion between vesicles and cell membranes, lipid exchange between the membranes, or vesicle fission. Identification of single events and t
BACKGROUND: Oestrogen receptor alpha (ER) is involved in cell growth and proliferation and functions as a transcription factor, a transcriptional coregulator, and in cytoplasmic signalling. It affects, for example, bone, endometrium, ovaries and mammary epithelium. It is a key biomarker in clinical management of breast cancer, where it is used as a prognostic and treatment-predictive factor, and a
α-Synuclein (α-Syn), is an intrinsically disordered protein present in the substantia nigra part of the brain. α-Syn is commonly known to associate with lipid membranes containing anionic lipids. Hence, the protein is hypothesized to be involved in the vesicle trafficking at the synapses, but there are yet many unanswered questions regarding the full physiological role of the protein. During the d
During the past decade, many parliamentary democracies have experienced bargaining delays when forming governments. The previous literature has attributed protracted government formation processes to a high degree of preference uncertainty among the political parties and a high level of bargaining complexity. The article draws on such theories, but also adds a third theoretical mechanism, commitme
[The project Millora 2.0: Results 2018–2022] Based on repeated yearly surveys of the vascular plant flora in 120 hectar plots in the province of Scania, southernmost Sweden, analysed in combination with speciesspecific traits and ecological indicator values (EIVs), changes in the flora and vegetation over the last four years are reported. Many of the changes observed, such as significant increasesBased on repeated yearly surveys of the vascular plant flora in 120 hectar plots in the province of Scania, southernmost Sweden, analysed in combination with speciesspecific traits and ecological indicator values (EIVs), changes in the flora and vegetation over the last four years are reported. Many of the changes observed, such as significant increases in lightdemanding, shortlived, pollinatorind
Why do some individuals feel hostility and express bias against supporters of other political parties? Drawing on intergroup threat theory, we examine the role of emotions as a mechanism by which perceived threats against the ingroup are a source of increased affective polarization. In two survey experiments performed in the multiparty contexts of Sweden (N = 505) and Germany (N = 776), we manipul
Introduction: How does threat motivate political choices? An extensive literature has noted the importance of threat in influencing political behavior. A growing literature in political psychology has used the concept of “mortality salience” to examine the role of existential threat in political decisions. Scholars have argued that inducing mortality salience by asking individuals to think about t
Why do political parties negotiate coalition agreements? Many coalition cabinets negotiate lengthy coalition contracts outlining the agenda for the time in office. Negotiating such an agreement not only takes time and resources, but compromises have to be made which may result in cabinet conflicts and electoral costs. We argue that coalition agreements are important control devices that allow coal
Diagnosis and treatment of patients with suspected chronic coronary syndrome (CCS) currently relies on the degree of coronary artery stenosis and its significance for myocardial perfusion. However, myocardial perfusion can be affected by factors other than coronary stenosis. The aim of this study was to investigate to what extent sex, age, diabetes, hypertension and smoking affect quantitative myo
Recent research has used the work of Douglas North as the foundation on which the case of institutions as ultimate driver of development could be built.North describes institutions as 'the humanly devised constraints that shape human interaction'. These arepowerful metaphors for us who are accustomed to think in terms of'constrained maximization' as the rule guiding personal actions. This book exp
This paper draws on the codes of ethics of a wide range of countries to propose an ideal one for a newly constituted press regulatory body in the United Kingdom. It also suggests the adoption of a codes of ethics and including a conscience clause in press journalists’ contract which would protect them from being coerced into doing clearly unethical work.
This interview is part of a major research project that is based on interviews and discussions with influential decision-makers, facilitators, mediators and negotiators who were involved in Arab-Israeli peace negotiations over the past three decades, as well as on archival research in Oslo, London, Washington and Jerusalem. Semi-structured in-depth interviews were conducted with more than 80 Israe
BackgroundMost jurisdictions that allow euthanasia and assisted suicide (AS) regulate it through the medical profession. However, the extent and nature of how medicine should be involved are debated. Swiss AS practice is unusual in that it is managed by lay AS organizations that rely on a law that permits AS when done for nonselfish reasons. Physicians are not mentioned in the law but are usually
Accurate statistical characterization of electromagnetic propagation is necessary for the design and deployment of radio systems. State-of-the-art channel models such as the Enhanced COST 2100 Channel Model utilize the concept of clusters of multipath components, and characterize channels by their inter- and intra-cluster statistics. Automatic clustering algorithms have been proposed in literature
Stored energies of radiating systems have generated research interest for several decades due to their relationship with Q-factor and fractional bandwidth. In this paper material derivatives are used to provide a new interpretation of widely used stored energy expressions. This provides a fundamental relationship between stored energies of radiating systems and their electromagnetic material prope
De senaste åren har Havs- och vattenmyndigheten minskat den mängd siklöja som får fångas i Bottenviken. Minskningen beror på att beståndet av siklöja har minskat. Siklöjan fiskas framförallt för att framställa löjrom. Det innebär att fiskarnas intäkter är starkt beroende av priset på löjrom. Mindre fångster innebär lägre intäkter för fiskarna om inte priset på löjrom samtidigt stiger kraftigt.I de
