BACKGROUND: The advent of PD-1/PD-L1 inhibitors has revolutionized lung cancer treatment, necessitating accurate PD-L1 immunohistochemical (IHC) assessment. While standardized for formalin-fixed paraffin-embedded (FFPE) histological samples, PD-L1 testing on cytology remains challenging. This review aims to address the complexities of PD-L1 IHC in cytology, focusing on validation guidelines, quali

OBJECTIVE: To investigate associations between meniscal tear, bone marrow lesions (BMLs), and post-injury knee loading, with cartilage T2 relaxation times on knee magnetic resonance imaging (MRI) in the subacute phase following acute anterior cruciate ligament (ACL) injury.DESIGN: We studied both knees of 128 patients with ACL injury. The presence of meniscal tears and BMLs were determined on suba

OBJECTIVES: To evaluate whether suicidality was documented prior to suicide in patients in contact with specialised somatic healthcare providers for physical conditions and to identify factors related to such documentation.DESIGN AND SETTINGS: Retrospective cohort study in which medical records from specialised somatic (non-psychiatric) healthcare services (internal medicine, infectious disease, s

OBJECTIVE: Cone beam computed tomography (CBCT) can accurately assess erosive disease in the hands, wrists and feet in established rheumatoid arthritis (RA). The aim of this study was to compare CBCT with conventional radiography (CR) for the assessment of erosions in patients with early RA.METHODS: CBCT and CR of the hands, wrists and feet of 17 patients with treatment naive early RA were assesse

Reliable maritime communication systems are essential for both safety-critical operations and emerging applications such as autonomous shipping, remote pilotage, and drone-assisted search and rescue. These scenarios demand ultra-reliable, low-latency wireless connectivity, where communication outages are unacceptable. Equally important is the need for dependable positioning systems. In situations

Direct injection (DI) hydrogen internal combustion engines are gaining attention as a promising technology for a sustainable energy transition, particularly in the transport sector. A key factor in improving the performance of these engines is understanding how hydrogen jets behave within the combustion chamber, especially their interactions with the chamber walls. These jet-wall interactions are

The article introduces the topic of reflective practice for a fire engineering audience. It first presents an overview of selected theory for reflection before connecting how they relate to engineering practices. In the second half, the author shares an example of a recent encounter in a project, how it relates to an older experience, and how he reflects upon it. Lastly, a personal view towards hi

This article explores the various manifestations of analogue video in digital culture. Introducing the framing concept of an aesthetics of remanence, it argues that the "society of the spectacle" (Debord) has entered an age of retrospectacle, a dominant signifier of which is the remediation and/or simulation of analogue videography. The concept of remanence connects the material conditions of magn

In this article, populism is approached as a political alternative that has to be taken seriously. This implies going beyond socio-economic or cultural explanations for populism’s growing popularity. The aim is to understand the reasoning in populist thought, the populist idea. Starting from a simple definition of populism, I then relate to populism as a ‘thin ideology’ or as a ‘political style’.

There can be situations, for example if gas containers have been damaged in a vehicle crash, when the fire and rescue service would like to depressurize the gas containers through shooting with a civilian rifle. Modern high-pressure hydrogen containers are designed for a working pressure of 700 bars. This means that they have a very thick and strong shell made of composite material. At the same ti

The EU AI Act aims to regulate artificial intelligence (AI) in a way that balances innovation and protection from harms, but faces the challenge of keeping pace with the development of AI. This paper examines the tension between fixity and flexibility when regulating AI in the EU by drawing on literature on the pacing problem and anticipatory governance, contrasted by sociolegal theory on the impo

PurposeThis research aims to contribute to the knowledge related to youth’s media and information literacy (MIL) practices when encountering artificial intelligence (AI)-generated media in their everyday life. It specifically examines young people’s engagement with and understanding of deepfakes, seeking to explore their practices for navigating deepfakes in a daily setting.Design/methodology/appr

Ett antologikapitel om hur den tekniska utvecklingens samhällspåverkan beskrivs inom nationalekonomi respektive teknikhistoria samt hur begreppet stigberoende kan användas för att sammanföra de två perspektiven.

The speedy advancement of digital technologies in the last decade has introduced new tools, workflows and stakeholders in diplomacy, creating significant information demands and a state of “digital stress”. To navigate these challenges, diplomats employ coping strategies that leverage their reflexivity and autonomy to manage demands, prioritize tasks, and mitigate overload. Beyond merely adapting