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IDO gene expression induction by DNA methylation inhibitors

The aim was to study the effect of DNA methylation of CpG motifs in cancer cells and immune cells by use of the DNA methyltransferas (DNMT) inhibitor zebularine. In cancer cells it is known that genes can be silenced by chromosomal deletion(s). It is also known that genes can be silenced by DNA methylation or expression of micro-RNA. In cancer cells genes can also be overexpressed by chromosomal a

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Based on a survey of waste sorting behaviours and perceptions of residents in southern Sweden, we analyse how convenience provided to citizens, among various other factors, may affect the actual waste sorting activities.

Three methods for optimizing single-shortest path routing

Intra-domain routing in IP networks is based on the shortest path principle by assigning administrative weights (costs) to links. The resulting least-cost paths determine routes between pairs of routers. If several such equal-cost paths exist between a pair of routers, it may not be clear which of them is actually used to route traffic. This makes it difficult to predict the network traffic flow d

EFFECT OF THE FIELD MAPS ON THE BEAM DYNAMICS OF THE ESS DRIFT TUBE LINAC

In the beam dynamics design and modelling of the Eu- ropean Spallation Source (ESS) Drift Tube Linac (DTL) simplified models have been used for the focusing and ac- celerating elements. Since the high current requires precise control of the beam to analyze the losses it is useful to per- form the beam dynamics simulations by using accurate field maps of the focusing and accelerating elements. In t

The CFI Microsoft Judgment and TRIPS Competition Flexibilities

The CFI Microsoft judgment is the first decision handed down by any court situated in a WTO Member state that regards the competition rules in the TRIPS Agreement in order to partly justify the application of domestic competition laws to the exercise of intellectual property rights (IPRs). The TRIPS Agreement allows WTO Members to enact and apply national competition laws to IPR-related anti-compe