Dendritic cells (DC) are the most potent APC in the organism. Immature dendritic cells (iDC) reside in the tissue where they capture pathogens whereas mature dendritic cells (mDC) are able to activate T cells in the lymph node. This dramatic functional change is mediated by an important genetic reprogramming. Glycosylation is the most common form of posttranslational modification of proteins and h

OBJECTIVE: We sought to study changes in morphology and stent-graft configuration of descending thoracic aortic aneurysms after endovascular repair. METHODS: Twenty-three patients treated with custom-made stent-grafts were studied. The stent-graft consisted of continuous, stainless-steel Z stents mounted within a polyester graft. In the last 11 cases the stents were interconnected with 3 longitudi

Popular Abstract in Swedish Studiet av entreprenøren er ikke et studium om en «helt på sin hvite hest», som er en ikke uvanlig kritikk av vellykkete næringsdrivende, men snarere en analyse av helt vanlige menneskers tanker, drømmer og liv. Entreprenørene er vanskelige å finne for de er sjeldent forekommende i befolkningen. De er viktige fordi de utfører innovasjoner, som innebærer at man blir i stThis dissertation, which is an analysis of the entrepreneur at the micro level, supplements and underpins the understanding and use of the entrepreneur as an agent of social change in the analysis of economic change at the macro level. The aim of the thesis is firstly to seek out and identify businessmen of our time who claim to be innovative, and secondly to un-dertake a qualitative study and ana

Purpose: Good to excellent clinical results have been shown in the initial studies on osseointegrated metacarpophalangeal (MCP) and proximal interphalangeal (PIP) joint implants that consist of a flexible silicone spacer connected to osseointegrated titanium fixtures. A high fracture rate of the silicone spacer, however, has been reported, diminishing the value of this implant system. The purpose

Conditions for predicting the effects of intervention with certainty are derived. An outside observer studies sequences of actions from a two-person repeated prisoners' dilemma. The sequences are generated by finite automata, which are optimal at each stage of the game and also minimize the number of states. An intervention is a change of action for one of the players and a prediction is a stateme

Objective Arterial pulse contour analysis is gaining widespread acceptance as a monitor of continuous cardiac output (CO). While this type of CO measurement is thought to provide acceptable continuous measurements, only a few studies have tested its accuracy and repeatability under unstable hemodynamic conditions. We compared continuous CO measurement using the pulse contour method (PCCO) before a

Colonized bank voles (Clethrionomys glareolus) originating from Sweden developed type 1 diabetes. Animals became polydipsic, glucosuric, and hyperglycemic and gradually developed a lethal ketoacidosis. Pancreas in animals with end-stage disease showed total destruction of islet cells. Interestingly, also a high proportion of wild bank voles in cyclic populations that were trapped at (or close to)

Media coverage is often held responsible for the erosion of public support for European integration. At the same time, a well-functioning political journalism is also held up as an important requirement for EU democracy. Set against this background of confl icting perceptions of the media, this report analyzes political journalism’s critical performance in the realm of EU constitutionmaking. The r

Thiazolidinediones are antidiabetic agents that decrease insulin resistance. Emerging evidence indicates that they present beneficial effects for the vasculature beyond glycemic control. The aim of this open-label observational study was to determine the effect of the thiazolidinedione rosiglitazone on novel cardiovascular risk factors, namely, lipoprotein(a) [Lp(a)], C-reactive protein (CRP), hom

I artikeln presenteras Viktor Rydbergs journalistik i tidningen Tomtebissen från 1857. Därefter följer i helhet den första artikeln som Rydberg lät publicera i tidningen.

Recently, we and others reported a recurrent t(7;12)(q36;p13) found in myeloid malignancies in children < or =18 months of age and associated with a poor prognosis. Fluorescence in situ hybridization studies mapped the 12p13 breakpoint to the first intron of ETV6 and narrowed down the region of 7q36 involved. By using the sequences made public recently by the Human Genome Project, two candidate ge

The aim of this study was to characterize polypeptide components of the capture net spun by trichopteran larvae Hydropsyche slossonae (Banks) (Trichoptera: Hydropsychidae). Thirty-one polypeptide bands were identified by SDS - polyacrylamide gel electrophoresis (SDS-PAGE) from extracted net material, with molecular weights ranging from 8500 to 179 000. Comparison with published data on Bombyx mori

Rapporten innehåller sex från varandra fristående avsnitt som behandlar olika flödesproblem och styr- och reglertekniska frågor inom solvämetekniken. Ämnen som berörs är bl a flödesproblem i seriekopplade kollektorer, reglering av solkollektortemperatur och styrsystemets betydelse för insamlad solenergi.

Popular Abstract in Swedish Denna avhandling behandlar tre centrala områden i finansiell ekonomi i allmänhet och portföljvalsteori i synnerhet: riskmåttet, estimeringsrisk och tidsdiversifiering. Avhandlingen består av fem kapitel varav ett är ett kort introduktionskapitel. De första två kapitlen behandlar ett alternativt mått på risk, lower partial moment (LPM). Detta alternativa mått behandlar eThis thesis is devoted to the analysis of three important issues in financial economics in general and portfolio selection in particular: the risk measure, estimation risk and time diversification. Besides a short introductory chapter the thesis consists of four empirical essays. In the second chapter, the effect of estimation risk on the efficient frontier in the lower partial moment framework is