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Handla med medborgarskap?

Om alla människor hade möjlighet att välja medborgarskap, som man väljer bostad eller annan konsumtion, skulle vi implicit observera deras preferensergenom dessa beslut. Medborgarskap kan betraktas som privat men ej överlåtbar egendom. Om medborgarskapet blev överlåtbart och vi kunde handla meddem och hade en etablerad handelsplats – likt en aktiebörs – skulle vi kunna observera marknadspriser på

A generalist vector-transmitted parasite exhibits population genetic structure among host genera

Generalist parasites experience selective pressures from the various host species they infect. However, it is unclear if parasite transmission among host species precludes the establishment of host-specific adaptations and population genetic structure. We assessed the population genetic structure of the vector-transmitted avian haemosporidian parasite Haemoproteus majoris (lineage WW2; n = 34 infe

Embedded disposability : A cultural political economy of plastics

Plast präglar i stort sett allting i det moderna livet och bidrar till miljöförstöring och avfallsgenerering på global nivå. Denna avhandling undersöker hur plastavfall blev djupt inbäddat i Sveriges kulturella, politiska och ekonomiska strukturer. Med hjälp av ett ramverk baserat på kulturell politisk ekonomi (CPE) används tre perspektiv - hegemoni, inlåsningseffekter och praktiker - för att analPlastic disposability is a pervasive feature of modern life, contributing to environmental degradation and waste generation on a global scale. This dissertation investigates how plastic disposability became deeply embedded within Sweden's cultural, political, and economic structures. Using a Cultural Political Economy (CPE) framework, it applies three lenses – hegemony, lock-in, and practice – to

A Randomized, Placebo-Controlled, Single-Center, Crossover Study to Evaluate the Effects of Pre-Meal Whey Protein Microgel on Post-Prandial Glucometabolic and Amino Acid Response in People with Type 2 Diabetes and Overweight or Obesity

Purpose: Whey protein (WP) consumption prior to a meal curbs appetite and reduces postprandial glucose (PPG) through stimulating endogenous GLP-1 secretion and insulin. Methods: We assessed the metabolic effects of a concentrated WP, using a new micelle-technology (WPM), in people with type 2 diabetes (T2D) and overweight or obesity (NCT04639726). In a randomized-crossover design, participants per

The Role of Glial Cells in the Pathophysiology of Epilepsy

Epilepsy is a chronic neurological disorder marked by recurrent seizures, significantly impacting individuals worldwide. Current treatments are often ineffective for a third of patients and can cause severe side effects, necessitating new therapeutic approaches. Glial cells, particularly astrocytes, microglia, and oligodendrocytes, are emerging as crucial targets in epilepsy management. Astrocytes

Advanced electrocardiography heart age : a prognostic, explainable machine learning approach applicable to sinus and non-sinus rhythms

Aims: An explainable advanced electrocardiography (A-ECG) Heart Age gap is the difference between A-ECG Heart Age and chronological age. This gap is an estimate of accelerated cardiovascular aging expressed in years of healthy human aging, and can intuitively communicate cardiovascular risk to the general population. However, existing A-ECG Heart Age requires sinus rhythm. We aim to develop and pr

Dose-Response Relationship of Phloretin Therapy on Water and Glucose Transport during Experimental Peritoneal Dialysis

Background Water retention, ultrafiltration insufficiency, and metabolic complications due to abnormally high glucose concentrations are still common problems in patients treated with peritoneal dialysis. Phloretin, a nonselective inhibitor of facilitative glucose transporter channels (GLUT), has shown to improve water transport and lower glucose absorption in experimental peritoneal dialysis. How

Beyond Survival : Unveiling Psychological and Social Adaptation After Visceral Transplantation

Aim: To explore the meaning of adaptation after visceral transplantation in terms of patient experiences, symptoms, self-efficacy, transplant-specific and mental well-being. Design: A convergent parallel mixed-methods study, consisting of interviews and generic as well as transplant-specific questionnaires. Results were integrated using meta-inference. Methods: The study comprises a population of

Continuous feedback protocols for cooling and trapping a quantum harmonic oscillator

Quantum technologies and experiments often require preparing systems in low-temperature states. Here we investigate cooling schemes using feedback protocols modeled with a quantum Fokker-Planck master equation (QFPME) recently derived by Annby-Andersson et al. [Phys. Rev. Lett. 129, 050401 (2022)0031-900710.1103/PhysRevLett.129.050401]. This equation describes systems under continuous weak measure

TOI-2458 b : A mini-Neptune consistent with in situ hot Jupiter formation

We report on the discovery and spectroscopic confirmation of TOI-2458 b, a transiting mini-Neptune around an F-type star leaving the main-sequence with a mass of M∗ = 1.05 ± 0.03 M⊙, a radius of R∗ = 1.31 ± 0.03 R⊙, an effective temperature of Teff = 6005 ± 50 K, and a metallicity of 0.10 ± 0.05 dex. By combining TESS photometry with high-resolution spectra acquired with the HARPS spectrograph, we

Association of Pulmonary Involvement at Baseline with Exercise Intolerance and Worse Physical Functioning 8 Months Following COVID-19 Pneumonia

Objectives: We aimed to describe the cardiopulmonary function during exercise and the health-related quality of life (HRQoL) in patients with a history of COVID-19 pneumonia, stratified by chest computed tomography (CT) findings at baseline. Methods: Among 77 consecutive patients with COVID-19 who were discharged from the Pulmonology Ward between March 2020 and April 2021, 28 (mean age 54.3 ± 8.6

Polygenic risk scores for atrial fibrillation and heart failure and the risk of stroke and dementia

Atrial fibrillation and heart failure have both been suggested to increase stroke and dementia risk. However, in observational studies, reversed causation and unmeasured confounding may occur. To mitigate these issues, this study aims to investigate if higher genetic risk for atrial fibrillation and heart failure increases dementia and stroke risk. Data were obtained from the population-based Goth

Modeling Sporadic Progressive Supranuclear Palsy in 3D Midbrain Organoids : Recapitulating Disease Features for In Vitro Diagnosis and Drug Discovery

Objective: Progressive Supranuclear Palsy (PSP) is a severe neurodegenerative disease characterized by tangles of hyperphosphorylated tau protein and tufted astrocytes. Developing treatments for PSP is challenging due to the lack of disease models reproducing its key pathological features. This study aimed to model sporadic PSP-Richardson's syndrome (PSP-RS) using multi-donor midbrain organoids (M

Implications of Regulating a Moving Target: Between Fixity and Flexibility in the EU AI Act

The EU AI Act aims to regulate artificial intelligence (AI) in a way that balances innovation and protection from harms, but faces the challenge of keeping pace with the development of AI. This paper examines the tension between fixity and flexibility when regulating AI in the EU by drawing on literature on the pacing problem and anticipatory governance, contrasted by sociolegal theory on the impo

Chest pain in the emergency department - risk assessment, diagnostics, and outcomes

Chest pain is one of the most common reasons for emergency department (ED) visits. Extensive diagnostic testing is often performed to identify acute coronary syndrome (ACS), but only about 10% of patients ultimately receive an ACS diagnosis. These diagnostic processes are costly, time-consuming, and sometimes invasive, carrying inherent risks. Additionally, most patients with suspected ACS are adm

A Novel Decentralized Leader–follower Control Scheme for Centroid and Formation Tracking

This paper deals with the centroid and formation control problem of multi–agent robotic systems. The proposed solution is based on a leader–follower scheme, where only a subset of agents, i.e., the leaders, knows the desired trajectories for the centroid and the formation of the system, while the other agents, i.e., the followers, are required to estimate them through a dynamic consensus scheme. T