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A Description of the Valley of Chamouni, in Savoy [Scholarly Edition]

An online, multimedia edition of 'A Description of the Valley of Chamouni, in Savoy' (1819), by Samuel Glover. This edition brings to light a forgotten and important work of travel literature about Chamonix-Mont Blanc, and documents its close connections with the activities of Mary and Percy Shelley during to the so-called 'Frankenstein Summer' of 1816, and with high-profile exhibitions about Cham

Cuneate spiking neural network learning to classify naturalistic texture stimuli under varying sensing conditions

We implemented a functional neuronal network that was able to learn and discriminate haptic features from biomimetic tactile sensor inputs using a two-layer spiking neuron model and homeostatic synaptic learning mechanism. The first order neuron model was used to emulate biological tactile afferents and the second order neuron model was used to emulate biological cuneate neurons. We have evaluated

Electrophysiological responses of carrot psyllids (Trioza apicalis), in different phases of their life cycle, to volatile carrot and conifer compounds

Carrot psyllids (Trioza apicalis) pose a constant threat to carrot production in parts of Europe, and treatments with chemical insecticides are common. To be able to develop alternative control tactics, more knowledge about the psyllid's host-finding behaviour and underlying physiology is needed. Using single-sensillum recordings from overwintered and non-overwintered males and females, we found e

Process designs for novel pervaporation-based hybrid-processes to recover organic compounds from waste water

IntroductionAn overview of the different hybrid-processes combining pervaporation with a conventional separation as a tool to recover organic compounds from waste water will be given. Analysing potential applications shows that pervaporation alone will rarely be economical due to the purity required nowadays in waste water treatment. The limitation on flux owing to the activity being the driving f

Lipid Dynamics and Phase Transition within α-Synuclein Amyloid Fibrils

The deposition of coassemblies made of the small presynaptic protein, α-synuclein, and lipids in the brains of patients is the hallmark of Parkinson's disease. In this study, we used natural abundance 13C and 31P magic-angle spinning nuclear magnetic resonance spectroscopy together with cryo-electron microscopy and differential scanning calorimetry to characterize the fibrils formed by α-synuclein

A pilot study of hypertension management using a telemedicine treatment approach

We recruited 78 men and 94 women to investigate if the proportion of subjects with well-controlled home blood pressure levels could be increased when treatment was guided by smartphone-based telemonitoring. All patients were prescribed one to three antihypertensive drugs. The Accumbo smartphone telemonitoring application was downloaded to the Iphones of the participants and home blood pressure inf

Data centres in future European energy systems—energy efficiency, integration and policy

End-use efficiency, demand response and coupling of different energy vectors are important aspects of future renewable energy systems. Growth in the number of data centres is leading to an increase in electricity demand and the emergence of a new electricity-intensive industry. Studies on data centres and energy use have so far focused mainly on energy efficiency. This paper contributes with an as