Filtyp
Context: Clinically assisted hydration during end-of-life care among patients with cancer is controversial; practice varies between clinical settings and countries, and there is a lack of evidence. Objectives: To examine whether breathlessness, respiratory secretion, or confusion correlates with receiving parenteral hydration during end of life, adjusted for sex, age, and place of death. Methods:
The dating of moraine deposits can present challenges to standard geochronological methods; terrestrial cosmogenic nuclide (TCN), sediment luminescence and radiocarbon dating may suffer from problems of incomplete resetting (by inheritance, intermittent cover/exposure, transport under unfavourable conditions) and/or a lack of suitable (organic) material. Rock surface luminescence burial dating (RS
The doctorate forms the basis for academic careers and the regeneration of academia, and has increasingly become important for other sectors of society. The latter is reflected in efforts on institutional, national as well as supranational levels to change and adapt the doctoral degree to new expectations. As doctoral education is embedded in research, changes in governance and funding of research
OBJECTIVE: To estimate patient acceptable symptom state (PASS) and treatment failure (TF) threshold values for Work Productivity and Activity Impairment (WPAI) measure and EQ-5D-5L among people with hip or knee osteoarthritis (OA) 3 and 12 months following participation in a digital self-management intervention (Joint Academy®).METHODS: Among the participants, we computed work and activity impairm
Background: Intact cord resuscitation in the first three minutes of life improves oxygenation and Apgar scores. The practise of intact cord resuscitation implies the umbilical cord still being connected to the placenta for at least one minute while providing temperature control and equipment for resuscitation. Healthcare professionals described practical challenges in providing intact cord resusci
Introduction: Reporting of hypoglycaemia and its impact in clinical studies is often retrospective and subject to recall bias. We developed the Hypo-METRICS app to measure the daily physical, psychological, and social impact of hypoglycaemia in adults with type 1 and insulin-treated type 2 diabetes in real-time using ecological momentary assessment (EMA). To help assess its utility, we aimed to de
Graves’ disease (GD) and Graves’ ophthalmopathy (GO) are complex autoimmune diseases. This study delved into the impact of cigarette smoke extract (CSE), simvastatin, and/or diclofenac on peripheral blood mononuclear cells (PBMCs). Specifically, we explored alterations in IL-1B, IL-6, PTGS2 expression, B-and T-lymphocyte proliferation, and Immunoglobulin G (IgG) production. We also assessed IGF1’s
Introduction: There are few large registry-based studies comparing disease prevalence among people with intellectual disabilities (ID) compared to general populations, despite older people with ID having more comorbidities and health care utilization. This study aimed to explore differences in prevalence of dementia and age at first diagnosis between people with ID and the general population in Sk
BackgroundThere is a growing body of evidence indicating that second degree tears cause both short-, and long-term consequences. Very few preventative measures have been found to reduce the incidence of these tears.ObjectiveTo investigate if the use of a perineal protection device during vaginal birth reduces severe perineal tearing (≥grade 2 tear) in primiparous women compared to routine manual p
Agricultural intensification and expansion are regarded as main drivers of biodiversity loss. This conclusion is mainly based on observed declines of local diversity (α-diversity), while effects on community composition homogenization (decrease of β-diversity) at a larger spatial scale are less well understood. Carabid beetles and spiders represent two widespread guilds and are important predators
Changes in land cover, particularly agricultural intensification, are a primary cause of pollinator decline. Decline and isolation can reduce genetic diversity, reducing adaptive potential and unmasking genetic load. Maintenance of functional connectivity in changing landscapes is necessary to ensure persistence, but how land cover impacts genetic diversity and functional connectivity in butterfli
The European spruce bark beetle ( Ips typographus L.) is a biotic disturbance that devastates forest environmental services, and its activities are exacerbated due to climate change. Accordingly, researchers seek workflows using remote sensing imagery for bark beetle detection in the early stage of the attack, enabling proactive management. Most previous studies attempted to detect attacks with pi
Due to climate change, future weather conditions will become more extreme. During recent years, several severe damages have been caused by heavy rainfalls in combination with riverine events. Even though the effects of compound events are known to be influential for flood hazard, the method for investigating these types of events is a novel area of expertise. In this study, a methodology was devel
