Filtyp
Populärvetenskaplig sammanfattning: Övergödningen av våra kustnära hav blev akut under 1980-talet, syrefria bottnar och giftiga algblomningar visade tydligt att något var mycket fel. Kväve, ett näringsämne, visade sig vara en av huvudorsakerna till dessa reaktioner i havet. De största kvävespridarna i Sverige var jordbruk och reningsverk. Avloppsvattenhanteringen behövde förändras och ett sätt att
Populärvetenskaplig sammanfattning: Flera olika klimatsimuleringar har visat på en sannolik förändring av jordens klimat, till största delen beroende på utsläpp orsakade av mänsklig aktivitet. Eftersom klimatet påverkar såväl ekosystem som livsmiljö är det av största intresse att kartlägga vilka konsekvenser en eventuell klimatförändring kan få. Även om människans vardag för det mesta påverkas av
OBJECTIVE To characterize distinct islet autoantibody profiles preceding stage 3 type 1 diabetes RESEARCH DESIGN AND METHODS The T1DI (Type 1 Diabetes Intelligence) study combined data from 1,845 genetically susceptible prospectively observed children who were positive for at least one islet au-toantibody: insulin autoantibody (IAA), GAD antibody (GADA), or islet antigen 2 antibody (IA-2A). Using
Some studies suggest that elite athletes experience adverse mental health symptoms at rates commensurate with the general population, despite the well-established buffering effects of exercise. Within contact sports, such as ice-hockey, recurrent concussions may be a source of this discrepancy. We compared the point prevalence of various mental health outcomes with other athlete and general popula
OBJECTIVES: Most patients with pancreatic cancer who have undergone surgical resection eventually develop disease recurrence. This study aimed to investigate whether there is evidence to support routine surveillance after pancreatic cancer surgery, with a secondary aim of analyzing the implementation of surveillance strategies in the Nordic countries.MATERIALS AND METHODS: A scoping review was co
Background: Staphylococcus aureus bacteraemia (SAB) may lead to periprosthetic joint infections (PJI) via haematogenous spread of bacteria to the joint. Due to the risk of PJI, patients with SAB and prosthetic joint are recommended prolonged antibiotic treatment. The aim of the study was to assess the risk of PJI during SAB, and to evaluate if short treatment duration affects outcomes in patients
Background: Few neuroimaging studies have investigated structural brain differences associated with variations in pain distribution. Objective: To explore structural differences of the brain in fibromyalgia (FM), temporomandibular disorder pain (TMD) and healthy pain-free controls (CON) using structural and diffusion MRI. Methods: A case–control exploratory study with three study groups with diffe
BACKGROUND: The scapular free flap has increasingly gained popularity as an alternative to the fibular free flap in osseous head and neck reconstruction. The present study aimed to evaluate their use in maxillomandibular reconstructions and examine surgical and patient outcomes.METHODS: Osseous head and neck defects reconstructed with an angular artery-based scapular flap or fibular flap from 2016
In-situ remediation through the injection of bioremediation fluids is becoming increasingly common for treating contaminated sites. Contaminants are targeted for treatment either directly at the source zone or through injections that form a permeable reactive barrier to prevent further transport of the contaminants. Commonly, multiple injections are performed in a grid covering an area of strategi
Chemotherapy persists as the primary intervention for breast cancer, with chemoresistance posing the principal obstacle to successful treatment. Herein, we show that cartilage oligomeric matrix protein (COMP) expression leads to increased cancer cell survival and attenuated apoptosis under treatment with several chemotherapeutic drugs, anti-HER2 targeted treatment, and endocrine therapy in several
Den här avhandlingen utforskar incesttabuts politiska natur genom att analytiskt fokusera på dess förbudsobjekt: incest. Från ett politiskfilosofiskt perspektiv framstår incesttabut som ett problem som handlar om att människans otyglade natur på olika sätt måste begränsas genom en grundläggande civiliserande lag. Följaktligen verkar incesttabuts auktoritet knytas till dess förmåga att utesluta tenThis dissertation explores the political nature of the incest taboo, with an analytical focus on its object of prohibition: incest. From the perspective of political philosophy, the incest taboo appears as problem of an unruly human nature that must be subjected to a foundational civilizing law. To this end, the taboo’s authority seems to derive from its ability to evict tendencies and desires tha
OBJECTIVE: Nonmotor symptoms are common in Parkinson's disease (PD). Health-related quality of life (HRQoL) is negatively affected by different factors, of which pain and sleep disturbances are important contributors. This study was performed to evaluate and describe subjective experiences of pain, sleeping patterns, and HRQoL in a cohort of PD patients with chronic pain.METHODS: A total of 45 par
AbstractIntroductionConservative treatment of acute appendicitis is gaining popularity, and identifying patients with a higher risk of recurrence is becoming increasingly important. Previous studies have suggested that older age, male sex, diabetes, appendicolith and abscess formation may be contributing factors, however, results from the adult population are inconsistent.AimThis study aims to ide
Introduction: Several studies have addressed technical aspects of endovascular thrombectomy (EVT), but it is not well known how procedural factors contribute to technical success in routine healthcare. The aim was to explore factors associated with technically successful EVT on nationwide scale. Methods: We did an observational register-based study assessing factors associated with technical succe
There are substantial concerns about impaired honey bee health and colony losses due to several poorly understood factors. We used MALDI profiling (MALDI BeeTyping®) analysis to investigate how some environmental and management factors under field conditions across Europe affected the honey bee haemolymph peptidome (all peptides in the circulatory fluid), as a profile of molecular markers represen
Background: There is an unmet clinical need for novel therapies addressing the residual risk in patients receiving guideline preventive therapy for coronary heart disease. Experimental studies have identified a pro-atherogenic role of the oxidized LDL receptor LOX-1. We investigated the association between circulating soluble LOX-1 (sLOX-1) and the risk for development of myocardial infarction. Me
Diabetes mellitus (DM) is a risk factor for the development of ulnar nerve entrapment (UNE). Differences in surgical outcomes for UNE between patients with and without DM have been reported, but studies on presurgical management are scarce. This study aimed to evaluate the presurgical management of UNE in patients with (DM diagnosis < 2 years of UNE diagnosis) and without DM regarding the level of
In times of escalating global environmental crises and subsequent troubling emotional experiences, it is imperative to understand the psychological mechanisms through which people cope. Although it is increasingly recommended to talk about global environmental change and the emotions it evokes as a way of coping with its overwhelming and existential nature, private-sphere conversations about clima
AIMS: Impaired left ventricular-arterial coupling (VAC) has been shown to correlate with worse prognosis in cardiac diseases and heart failure (HF). The extent of the relationship between VAC and circulating biomarkers associated with HF has been scarcely documented. We aimed to explore associations of VAC with proteins involved in HF pathophysiology within a large population-based cohort of middl
