We performed fine mapping of 39 established type 2 diabetes (T2D) loci in 27,206 cases and 57,574 controls of European ancestry. We identified 49 distinct association signals at these loci, including five mapping in or near KCNQ1. 'Credible sets' of the variants most likely to drive each distinct signal mapped predominantly to noncoding sequence, implying that association with T2D is mediated thro

System cost reductions and development of standardised plug-and-function systems are some of the most important goals for solar heating technology development. Retrofitting hot water boilers in single-family houses when installing solar collectors has the potential to significantly reduce both material and installation costs. In this study, the TRNSYS simulation models of the retrofitting solar th

Cyanobacteria living epiphytically on mosses in pristine, unpolluted areas fix substantial amounts of atmospheric nitrogen (N) and therefore represent a primary source of N in N-limited boreal forests. However, the fate of this N is unclear, in particular, how the fixed N-2 enters the soil and becomes available to the ecosystem. In this study, we applied N-15-ammonium chloride (N-15-NH4Cl) onto ca

Background: In previous meta-analyses, tea consumption has been associated with lower incidence of type 2 diabetes. It is unclear, however, if tea is associated inversely over the entire range of intake. Therefore, we investigated the association between tea consumption and incidence of type 2 diabetes in a European population. Methodology/Principal Findings: The EPIC-InterAct case-cohort study wa

Differential heating of surface waters of lakes caused by shading from vegetation can induce convection, which could be significant for the ecosystem because the chemistry and biology can differ in the reed belt zone compared to the open lake. This process has been given little attention in the literature. In the present study surface currents just outside a reed belt as well as radiation and wate

This dissertation examines aspects of the experience of being a student at Nääs’ sloydseminar between 1880 and 1940 and what consequences it had for the participants. The experience was more or less consciously constructed by the charismatic leader Otto Salomon and after his death in 1907 the responsability of ”composing” the experience was put on Rurik Holm, pedagogical manager between 1913 and 1

In recent work on international comparisons of income-related inequalities in health, the concentration index has been used as a measure of health inequality. A drawback of this measure is that it is sensitive to whether it is estimated with respect to health or morbidity. An alternative would be to use the generalized concentration index that is based on absolute rather than relative health diffe

BackgroundCushion bush [Leucophyta brownii Cass.=Calocephalus brownii (Cass.) F. Muell.] is an Australian Compositae shrub that has been introduced into Scandinavia as a pot plant. The first case of sensitization occurred in a gardener, and the main allergen was identified as the guaianolide calocephalin. ObjectiveTo present the identification of the main allergen, and to assess the prevalence of

A number of studies stress the importance of positive mealtime experiences for nursing home residents. However, the components that comprise an ideal nursing home meal remain unclear, reflecting the ambiguity of whether nursing homes should be framed as institutions, domestic settings or a type of hotel. In this study, nursing home meals were viewed as situations that the involved parties could co