The aim of this study was to examine the experiences of adopted adults concerning their childhood, the search for origin and opinions on adoption and what influence these aspects have had on their lives. The method used was semi-structured interviews and the people interviewed were all adopted adults. To analyse our results we used John Bowlby´s “attachment theory”. During our interviews another a

The Purpose of this survey was to look at the social meaning of alcohol within a group of young people in the age area 18 to 20. I chose a quantitative survey among youth to investigate attitudes to alcohol habits of other youths. The survey was performed with 96 young persons. Every year the federation of alcohol and drug awareness (CAN) do a nationwide survey of alcohol and drug habits among stu

We wanted to examine children's views on families and traditions surrounding family formation. Our main questions were; What are children's views on the concept "family" and how does this compare to the different definitions of family? How traditional or modern are children in comparison with historical and present views? and What are the effects of their own experiences, and val

The aim of this report is to provide a detailed description of the eight development projects recommended for the first strategy period (2021-2023) of the project “A National Strategy for Standardisation of Digital Information Management within the Built Environment”. The report also contains a description of the vision and the objectives of the strategy. The project has been led by Pontus Bengtso

Reduced glomerular filtration rate defines chronic kidney disease and is associated with cardiovascular and all-cause mortality. We conducted a meta-analysis of genome-wide association studies for estimated glomerular filtration rate (eGFR), combining data across 133,413 individuals with replication in up to 42,166 individuals. We identify 24 new and confirm 29 previously identified loci. Of these

Extreme weather events like floods are expected to become more common asclimate change continues, putting health at risk. Systems should be able tocontinue delivering essential health services when shocked by events like floodsand provide care for the expected new health needs caused by the shock.Resilient health systems have the capacity to maintain their functions and tochange when shocked, enab

Introduction: The relationship between urate and biomarkers for Alzheimer's disease (AD) pathophysiology has not been investigated. Methods: We examined whether serum concentration of urate was associated with cerebrospinal fluid biomarkers, amyloid beta (Aβ)42, Aβ40, phosphorylated tau (p-tau), total tau (t-tau), neurofilament light (NfL), and Aβ42/Aβ40 ratio, in cognitively unimpaired 70-year-ol

Upstream open reading frames (uORFs) are tissue-specific cis-regulators of protein translation. Isolated reports have shown that variants that create or disrupt uORFs can cause disease. Here, in a systematic genome-wide study using 15,708 whole genome sequences, we show that variants that create new upstream start codons, and variants disrupting stop sites of existing uORFs, are under strong negat

Aquaporins play a crucial role in water homeostasis in the human body, and recently the physiological importance of aquaporins as glycerol channels have been demonstrated. The aquaglyceroporins (AQP3, AQP7, AQP9 and AQP10) represent key glycerol channels, enabling glycerol flux across the membranes of cells. Adipocytes are the major source of glycerol and during lipolysis, glycerol is released to

Hundreds of thousands of genetic variants have been reported to cause severe monogenic diseases, but the probability that a variant carrier develops the disease (termed penetrance) is unknown for virtually all of them. Additionally, the clinical utility of common polygenetic variation remains uncertain. Using exome sequencing from 77,184 adult individuals (38,618 multi-ancestral individuals from a