White adipose tissue (WAT) plays an important role in the integration of whole-body metabolism by storing fat and mobilizing triacylglycerol when needed. The released free fatty acids can then be oxidized by other tissues to provide ATP. AMP-activated protein kinase (AMPK) is a key regulator of metabolic pathways, and can be targeted by a new generation of direct, small-molecule activators. AMPK a

Rinodina pityrea and R. colobina are reported as two distinct species with differing ecology and morphological characters. Molecular analysis of their ITS and mrSSU genes show that R. pityrea and R. colobina are two clearly separated species. Furthermore, the two species are morphologically and geographically distinct in the Nordic countries and can usually be recognized with a hand lens rather th

A circular economy (CE) calls for the value of materials and products to be maintained and recovered through narrowing, closing, and slowing loops. However, there remain challenges in capturing value through reuse of components in refurbished and repaired products. In this paper, we provide an overview of the research and practice of harvesting spare parts from used and waste electrical and electr

Syftet med denna översiktsartikel är att sätta in matdistribution till personeri fattigdom i ett sammanhang, för att bättre förstå dess betydelse för mottagare,civilsamhällesorganisationer och i förlängningen även välfärdsmodelleni Sverige. Artikeln synliggör en förändring där ett ökat behov av kostnadsfrieller billig mat för fattiga grupper möts av ett ökat utbud av mat distribuerat avcivilsamhäl

The mixed embeddedness (ME) perspective offers a holistic approach to understanding entrepreneurship as embedded in a myriad of contexts. Alone, however, it is not capable of explaining the dynamic interrelations between entrepreneurship and opportunity structures beyond venture start-up. We offer a synthesis between ME and the dynamic states approach, using the concept of opportunity tension to e

Previous research has argued that related variety enhances regional innovation as inter-industry knowledge spillovers occur more easily between cognitively similar industries. In this study, we engage with empirical operationalization of what is ‘related’ in related variety. We argue, based on theoretical grounds, that estimating regional knowledge production functions requires related variety mea

In anonymous online text-based counselling provided by social services, counsellors face specific communicative and professional challenges. Among other things, they need to ensure that they have understood the chat users correctly in order to provide relevant information and advice. The paper studies how counsellors check their understanding of users’ situations by using formulations, namely, sum

These interviews are part of a major research project that is based on interviews and discussions with influential decision-makers, facilitators, mediators and negotiators who were involved in the Israel-PLO peace negotiations over the past three decades, as well as on archival research in Oslo, London, Washington and Jerusalem. Semi-structured in-depth interviews were conducted with more than 80

Abstract in GermanDas Boot gilt als ein herausragendesSymbol der nordischen Bronzezeit, dargestellt in Tausendenvon Felsbildern und auf vielen Metallgegenständen in ganzSkandinavien. Paradoxerweise sind direkte Hinweise aufdiese Boote rar, und die Orte, an denen Boote gebaut wurden,bleiben größtenteils schwer fassbar. In diesem Artikel schla-gen wir vor, dass die sogenannten Kochgruben entlang derThe boat stands out as a prominent symbol of the Nordic Bronze Age, depicted at thousands of rock art sites and on several metal objects throughout Scandinavia. Paradoxically, direct evidence of these boats is scarce, and the locations where boats were constructed remain largely elusive. In this paper, we put forth the proposition that many ostensibly mislabelled cooking pits along the coast might

Chimney sweeps have higher incidence and mortality of cardiovascular disease (CVD), likely related to their exposure to polycyclic aromatic hydrocarbons (PAH). In order to identify underlying mechanisms of PAH-related CVD, we here investigated whether PAH exposure was associated with levels of putative CVD-related proteins in serum among currently working chimney sweeps. We enrolled 116 chimney sw

Shallow geothermal offers great potential to supply emission-free heating and cooling and has therefore a pivotal role in the transition of heating and cooling networks. This paper presents a novel heating and cooling network with possible geothermal energy sharing between decentralized borefields located at each building level. The system consolidates the benefits of both standalone and centraliz

There is an increasing need for new biomarkers to improve prediction of chronic kidney disease (CKD) in individuals with type 2 diabetes (T2D). We aimed to identify blood-based epigenetic biomarkers associated with incident CKD and develop a methylation risk score (MRS) predicting CKD in individuals with newly diagnosed T2D. DNA methylation was analyzed epigenome wide in blood from 487 individuals