Importance: The lack of an in vivo measure for α-synuclein (α-syn) pathology until recently has limited thorough characterization of its brain atrophy pattern, especially during early disease stages. Objective: To assess the association of state-of-the-art cerebrospinal fluid (CSF) seed amplification assays (SAA) α-syn positivity (SAA α-syn+) with magnetic resonance imaging (MRI) structural measur

This paper surveys Nordic historic studies on the distribution of income to highlight similarities and differences between Denmark, Finland, Norway, and Sweden in the evolution of income concentration and income inequality over more than 140 years. Our descriptive analysis allows for a decomposition where we identify the contribution of the income share of the richest 1 per cent and the distributi

This Editorial highlights an interesting study in the current issue of the Journal of Neurochemistry in which Zhou et al. report new data showing that the ablation of serine racemase increases local insulin production in neurons of the hippocampus. The authors explored some of the possible mechanisms mediating the interaction between dampening production of D-serine and the local synthesis of insu

Cancer is a life-threatening disease worldwide. Nanomedicine and nanodelivery systems are recently developed scientific field that employs specific materials in the nanoscale range to deliver drugs. Lipid-based nanoparticles are an ideal delivery system since they exhibit many advantages, including high bioavailability, self-assembly, formulation simplicity, and the ability to exhibit a plethora o

Previous research has established that organizations as well as TMTs tend to be homogeneous. It has, however, suggested three different explanations by which such homosocial reproduction occurs, i.e. existing individuals tending to reproduce their own characteristics in the selection decisions they make. One explanation regards the organization level, arguing that persons similar to the organizati

In analysing speeches made by legislators, this book provides theoretical and empirical answers to questions such as: Why do some Members of Parliament (MPs) take the parliamentary floor and speak more than others, and why do some MPs deviate more than others from the ideological position of their party? The authors evaluate their hypotheses on legislative speechmaking by considering parliamentary

The genome is often the conduit through which environmental exposures convey their effects on health and disease. Whilst not all diseases act by directly perturbing the genome, the phenotypic responses are often genetically determined. Hence, whilst diseases are often defined has having differing degrees of genetic determination, genetic and environmental factors are, with few exceptions, insepara

Importance: Excess alcohol consumption and alcohol use disorders (AUDs) are associated with substantially increased mortality. Efforts to reduce this toll require an understanding of their causes. Objective: To clarify the degree to which the excess mortality associated with AUDs arises (1) from the predispositions of the person who develops AUD (and which would likely be shared by close relatives

Debating the role of literature, and poetry in particular, in foreign language teaching (FLT), many scholars underscore the enormous potential represented by literature when it comes to developing the students’ critical thinking, analytical skills, ability to understand other cultures and emphatic attitude. Nevertheless, poetry represents a challenge within foreign language teaching. Focusing on m