It has been known for decades that risk factors for diabetes and cardiovascular disease (CVD) tend to cluster. Metabolic syndrome refers to this risk factor clustering for some of the more well-established and dangerous risk factors. This chapter provides a historical overview on the concept of the metabolic syndrome; describes the clinical criteria used in the definition of the metabolic syndrome

Cardiovascular disease (CVD) is the most common cause of death in industrialized countries. One underlying cause is atherosclerosis, which is a systemic disease characterized by plaques of retained lipids, inflammatory cells, apoptotic cells, calcium and extracellular matrix (ECM) proteins in the arterial wall. The biologic composition of an atherosclerotic plaque determines whether the plaque is

Oxidative stress plays a role in the onset and progression of a number of diseases, such as Alzheimer’s disease, diabetes and cancer, as well as ageing. Oxidative stress is caused by an increased production of reactive oxygen species and reduced antioxidant activity, resulting in the oxidation of glutathione. The ratio of reduced to oxidised glutathione is often used as a marker of the redox state

A full-scale inside out hollow fibre membrane module was operated in a pilot-scale water treatmentplant in Sweden for a period of 12 months from August 2013 to July 2014. Liquid chromatography–organic carbon detection (LC-OCD) chromatogram indicated the membranes could effectivelyremove 86% of dissolved organic carbon and 92% of humic substances from the feedwater. Routinecleaning-in-place was con

This paper examines the effect of competition on a firm's choice of opening hours in the motor vehicle inspection market. Competition affects the incentive inspection firms face when choosing opening hours, which influences the probability that consumers find service time that best matches their preferred time. We use 2SLS analyses to resolve the potential endogeneity of market entry decisions. Us

Knowledge externalities affect high and low growth firms differently. This paper develops two theoretical arguments. The knowledge equilibrium argument postulates that knowledge externalities weaken high growth firms for the benefit of low growth firms until performance differences vanish. The knowledge competition argument proposes that high growth firms are better positioned to identify, attract

We present an implementation of a general weight window generator for global variance reduction in Geant4 based applications. The implementation is flexible and can be easily adjusted to a user-defined model. In this work, the weight-window generator was applied to calculations based on an instrument shielding model of the European Spallation Source, which is currently under construction in Lund,